Ultrasensitive fluorescent detection of HTLV-II DNA based on magnetic nanoparticles and atom transfer radical polymerization signal amplification

Zheng, Xiaoke; Zhao, Liang; Wen, Dongxiao; Wang, Xiaolan; Yang, Huaixia; Feng, Weisheng; Kong, Jinming

doi:10.1016/j.talanta.2019.120290

Cited by 20 publications

(9 citation statements)

References 46 publications

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“… (1) Stability needs to be improved; (2) Easy to aggregate. ( Pastucha et al, 2019 ; Tiwari et al, 2015 ; Zheng et al, 2020 ) Silica nanoparticles (1) Uniform and controllable particle size; (2) High surface area; (3) Easily modifiable surface. (1) Sensitivity; (2) Selectivity; (3) Non-toxic and high biological affinity; (4) Low cost; (5) Quick detection.…”

Section: Viral Nucleic Acid Detection Based On Mofmentioning

confidence: 99%

Metal-organic frameworks for virus detection

Wang

et al. 2020

Biosensors and Bioelectronics

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Virus severely endangers human life and health, and the detection of viruses is essential for the prevention and treatment of associated diseases. Metal-organic framework (MOF), a novel hybrid porous material which is bridged by the metal clusters and organic linkers, has become a promising biosensor platform for virus detection due to its outstanding properties including high surface area, adjustable pore size, easy modification, etc. However, the MOF-based sensing platforms for virus detection are rarely summarized. This review systematically divided the detection platforms into nucleic acid and immunological (antigen and antibody) detection, and the underlying sensing mechanisms were interpreted. The nucleic acid sensing was discussed based on the properties of MOF (such as metal ion, functional group, geometry structure, size, porosity, stability, etc.), revealing the relationship between the sensing performance and properties of MOF. Moreover, antibodies sensing based on the fluorescence detection and antigens sensing based on molecular imprinting or electrochemical immunoassay were highlighted. Furthermore, the remaining challenges and future development of MOF for virus detection were further discussed and proposed. This review will provide valuable references for the construction of sophisticated sensing platform for the detection of viruses, especially the 2019 coronavirus.

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Section: Viral Nucleic Acid Detection Based On Mofmentioning

confidence: 99%

Metal-organic frameworks for virus detection

Wang

et al. 2020

Biosensors and Bioelectronics

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“…Zheng et al developed a fluorescent biosensor for the detection of human T-lymphotropic virus type II (HTLV-II) DNA based on MNPs and atom-transfer radical polymerization (ATRP) signal amplification. 158 The good performance of this biosensor is mainly due to the ATRP signal amplification, magnetic separation of MNPs, and high specificity of the DNA strands. In this study, they utilized the fluorescent substance 9-anthracenylmethyl methacrylate polymer (pAMMA) as the signal reporting unit and hairpin DNA as the capture probe for the detection of HTLV-II DNA.…”

Section: Other Magnetic Bioassay Methodsmentioning

confidence: 99%

Section: Other Magnetic Bioassay Methodsmentioning

confidence: 99%

Magnetic-Nanosensor-Based Virus and Pathogen Detection Strategies before and during COVID-19

Saha

et al. 2020

ACS Appl. Nano Mater.

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The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), is a threat to the global healthcare system and economic security. As of July 2020, no specific drugs or vaccines are yet available for COVID-19; a fast and accurate diagnosis for SARS-CoV-2 is essential in slowing the spread of COVID-19 and for efficient implementation of control and containment strategies. Magnetic nanosensing is an emerging topic representing the frontiers of current biosensing and magnetic areas. The past decade has seen rapid growth in applying magnetic tools for biological and biomedical applications. Recent advances in magnetic nanomaterials and nanotechnologies have transformed current diagnostic methods to nanoscale and pushed the detection limit to early-stage disease diagnosis. Herein, this review covers the literature of magnetic nanosensors for virus and pathogen detection before COVID-19. We review popular magnetic nanosensing techniques including magnetoresistance, magnetic particle spectroscopy, and nuclear magnetic resonance. Magnetic point-of-care diagnostic kits are also reviewed aiming at developing plug-and-play diagnostics to manage the SARS-CoV-2 outbreak as well as preventing future epidemics. In addition, other platforms that use magnetic nanomaterials as auxiliary tools for enhanced pathogen and virus detection are also covered. The goal of this review is to inform the researchers of diagnostic and surveillance platforms for SARS-CoV-2 and their performances.

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“…Magnetic nanoparticles (MNPs) have emerged as promising candidates to develop biosensors for the detection of the deadly respiratory viral infections [ Islam and Ahsan, 2020 ; Barnett et al, 2020 ]. Using MNPs different biosensing techniques have been developed such as magnetic resonance (NMR/MRI) [ Perez et al, 2003 ], fluorescence [ Zheng et al, 2020 ], electrochemical [ Khan et al, 2020 ], and rolling circle amplification [ Tian et al, 2020a ; Tian et al, 2020b ]. Further, compared to PCR-based DNA diagnosis, rolling circle amplification (RCA) is a simple and powerful technique.…”

Section: Biosensors For Covid-19 Diagnosismentioning

confidence: 99%

Prospects of nanomaterials-enabled biosensors for COVID-19 detection

Srivastava

Mishra

et al. 2021

Science of The Total Environment

128

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We are currently facing the COVID-19 pandemic which is the consequence of severe acute respiratory syndrome coronavirus (SARS-CoV-2). Since no specific vaccines or drugs have been developed till date for the treatment of SARS-CoV-2 infection, early diagnosis is essential to further combat this pandemic. In this context, the reliable, rapid, and low-cost technique for SARS-CoV-2 diagnosis is the foremost priority. At present reverse transcription polymerase chain reaction (RT-PCR) is the reference technique presently being used for the detection of SARS-CoV-2 infection. However, in a number of cases, false results have been noticed in COVID-19 diagnosis. To develop advanced techniques, researchers are continuously working and in the series of constant efforts, nanomaterials-enabled biosensing approaches can be a hope to offer novel techniques that may perhaps meet the current demand of fast and early diagnosis of COVID-19 cases. This paper provides an overview of the COVID-19 pandemic and nanomaterials-enabled biosensing approaches that have been recently reported for the diagnosis of SARS-CoV-2. Though limited studies on the development of nanomaterials enabled biosensing techniques for the diagnosis of SARS-CoV-2 have been reported, this review summarizes nanomaterials mediated improved biosensing strategies and the possible mechanisms that may be responsible for the diagnosis of the COVID-19 disease. It is reviewed that nanomaterials e.g. gold nanostructures, lanthanide-doped polysterene nanoparticles (NPs), graphene and iron oxide NPs can be potentially used to develop advanced techniques offered by colorimetric, amperometric, impedimetric, fluorescence, and optomagnetic based biosensing of SARS-CoV-2. Finally, critical issues that are likely to accelerate the development of nanomaterials-enabled biosensing for SARS-CoV-2 infection have been discussed in detail. This review may serve as a guide for the development of advanced techniques for nanomaterials enabled biosensing to fulfill the present demand of low-cost, rapid and early diagnosis of COVID-19 infection.

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Ultrasensitive fluorescent detection of HTLV-II DNA based on magnetic nanoparticles and atom transfer radical polymerization signal amplification

Cited by 20 publications

References 46 publications

Metal-organic frameworks for virus detection

Metal-organic frameworks for virus detection

Magnetic-Nanosensor-Based Virus and Pathogen Detection Strategies before and during COVID-19

Prospects of nanomaterials-enabled biosensors for COVID-19 detection

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