Ultrasensitive DNA biosensor for hepatitis B virus detection based on tin-doped WO3/In2O3 heterojunction nanowire photoelectrode under laser amplification

Nanomaterials for virus sensing and tracking

“…Similar stability is also observed when tin has been used as a dopant in heteroinjected WO 3 /In 2 O 3 nanowire photoelectrodes. 191,379 The tin heterogeneity intensified light absorption by the creation of exciton which allows a dynamic response. Due to this phenomenon, MoS 2 nanosheets increase the electrochemiluminescence of QDs from 27 000 to 76 000 (2.8 times).…”

SARS-CoV-2 Tests: Bridging the Gap between Laboratory Sensors and Clinical Applications

“…Other Materials for Electrical Sensors of Viruses. Apart from silicon-based materials, tin-doped WO 3 /In 2 O 3 nanowires can serve as virus biosensors, 121 having detected hepatitis B virus. For this, single-stranded DNA oligonucleotides were covalently immobilized on the sensor to detect the hybridization of complementary DNA in a label-free approach through electrochemical impedance spectral measurements.…”

Role of biomaterials in the diagnosis, prevention, treatment, and study of corona virus disease 2019 (COVID-19)

“…Instead of evaluating conductivity changes, NWbased platform can be utilized to detect specific molecules through the electrochemical impedance spectra (EIS). The development of DNA impedance-based label-free biosensors based on the use of tin-doped WO 3 /In 2 O 3 [137] nanowires and ellurium-doped ZnO nanowires [138] for the detection of Hepatitis B virus has been reported. Interestingly, Chowdhury et al proposed pulse-triggered ultrasensitive impedance-based biosensor composed of graphene quantum dots and gold-embedded polyaniline nanowires in which an external pulse was applied, during the hepatitis E virus accumulation phase, to increase expansion and sensitivity consequently [139].…”