“…The contrast medium behavior of lymph nodes in the case of malignant lymphomas and the different benign lymphadenopathies has only been minimally examined to date. However, the few results show that similarly to B-mode and color/ power Doppler sonography, contrast-enhanced ul-trasound seems to show significant overlapping between malignant lymphomas and inflammatory lymph nodes [20,21]. Necrotic zones and liquefied areas in lymph nodes, as particularly known in the case of squamous cell carcinoma, bacterial abscessforming lymphadenitis, and tuberculosis, can be effectively visualized with contrast-enhanced ultrasound as circumscribed vascularization defects because ultrasound contrast media remain strictly intravascular (20, own observation).…”