Ultrahigh numerical aperture meta-fibre for flexible optical trapping

Plidschun, Malte; Ren, Haoran; Kim, Jisoo; Förster, Ronny; Maier, Stefan A.; Schmidt, Markus

doi:10.1038/s41377-021-00491-z

Cited by 110 publications

(90 citation statements)

References 55 publications

(78 reference statements)

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“…All in all, we anticipate that the non-diffracting beam will continue to contribute to many of the biomedical application researches to overcome the light scattering and large penetration drawbacks. With the recent advances in metasurface design [164] and fabrication of optical fiber, it is possible to integrate the non-diffracting beam with optical fiber for easy delivery of the non-diffracting beam [165]. With the non-paraxial beams, it would be possible to further improve the axial resolution of the MABs in the volumetric two-photon imaging system [17,[19][20][21].…”

Section: Discussionmentioning

confidence: 99%

Non-Diffracting Light Wave: Fundamentals and Biomedical Applications

Ren

Tang

et al. 2021

Front. Phys.

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The light propagation in the medium normally experiences diffraction, dispersion, and scattering. Studying the light propagation is a century-old problem as the photons may attenuate and wander. We start from the fundamental concepts of the non-diffracting beams, and examples of the non-diffracting beams include but are not limited to the Bessel beam, Airy beam, and Mathieu beam. Then, we discuss the biomedical applications of the non-diffracting beams, focusing on linear and nonlinear imaging, e.g., light-sheet fluorescence microscopy and two-photon fluorescence microscopy. The non-diffracting photons may provide scattering resilient imaging and fast speed in the volumetric two-photon fluorescence microscopy. The non-diffracting Bessel beam and the Airy beam have been successfully used in volumetric imaging applications with faster speed since a single 2D scan provides information in the whole volume that adopted 3D scan in traditional scanning microscopy. This is a significant advancement in imaging applications with sparse sample structures, especially in neuron imaging. Moreover, the fine axial resolution is enabled by the self-accelerating Airy beams combined with deep learning algorithms. These additional features to the existing microscopy directly realize a great advantage over the field, especially for recording the ultrafast neuronal activities, including the calcium voltage signal recording. Nonetheless, with the illumination of dual Bessel beams at non-identical orders, the transverse resolution can also be improved by the concept of image subtraction, which would provide clearer images in neuronal imaging.

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Section: Discussionmentioning

confidence: 99%

Non-Diffracting Light Wave: Fundamentals and Biomedical Applications

Ren

Tang

et al. 2021

Front. Phys.

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“…Owing to the ultrathin, compact, and flat design of metasurfaces, multiple optical trapping potentials can be realized for parallel guiding and sorting of particles [20,52]. Moreover, our metasurface based on beam shaper can be directly integrated with fiber optic probes and microfluidic devices [60,62]. Moreover, a tunable metasurface based on beam shaper can be designed to adjust trapping potentials along the axial direction [63][64][65].…”

Section: Discussionmentioning

confidence: 99%

Cubic-Phase Metasurface for Three-Dimensional Optical Manipulation

et al. 2021

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The optical tweezer is one of the important techniques for contactless manipulation in biological research to control the motion of tiny objects. For three-dimensional (3D) optical manipulation, shaped light beams have been widely used. Typically, spatial light modulators are used for shaping light fields. However, they suffer from bulky size, narrow operational bandwidth, and limitations of incident polarization states. Here, a cubic-phase dielectric metasurface, composed of GaN circular nanopillars, is designed and fabricated to generate a polarization-independent vertically accelerated two-dimensional (2D) Airy beam in the visible region. The distinctive propagation characteristics of a vertically accelerated 2D Airy beam, including non-diffraction, self-acceleration, and self-healing, are experimentally demonstrated. An optical manipulation system equipped with a cubic-phase metasurface is designed to perform 3D manipulation of microscale particles. Due to the high-intensity gradients and the reciprocal propagation trajectory of Airy beams, particles can be laterally shifted and guided along the axial direction. In addition, the performance of optical trapping is quantitatively evaluated by experimentally measured trapping stiffness. Our metasurface has great potential to shape light for compact systems in the field of physics and biological applications.

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“…Such a combination has been addressed by Yang et al, [22] who demonstrated the realization of a plasmonic metalens on the core of a sophisticated microstructured fiber via focused ion-beam milling (i.e., large-core photonic crystal fibers) operating at a near-infrared wavelength. One application that particularly benefits from the implementation of MSs on fiber end faces, for example, is the remote optical trapping of microscopic particles, which has recently been reported by Plidschun et al, [23] who demonstrated the implementation of a high-numerical-aperture MS (numerical aperture [NA] > 0.88) on the tip of a commercial single-mode fiber for trapping individual bacteria within an aqueous environment.…”

Section: Doi: 101002/adpr202100100mentioning

confidence: 99%

Plasmonic Metalens‐Enhanced Single‐Mode Fibers: A Pathway Toward Remote Light Focusing

Zeisberger

Schneidewind

Hübner

et al. 2021

Advanced Photonics Research

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Optical fibers represent efficient and compact photonic devices for the transportation of light, with widespread use in numerous areas and emerging applications particularly within bioanalytics and quantum technology that demand to shape the light at the fiber end. A relevant challenge is to focus light remotely without bulk optical components, which is difficult to achieve using fibers with flat end faces. This example emphasizes the importance of functionalizing fiber end faces, which is currently addressed by technologies such as focused ion beam milling, [1] 3D printing, [2] self-assembly, [3] or microstructuring the interior of fibers. [4] Recently, wafer-compatible planarization strategies were introduced to use electron beam lithography (EBL) within the context of fiber functionalization. This has allowed, for instance, boosting light incoupling efficiencies into the fiber modes by orders of magnitude via periodic metallic or dielectric nanostructures. [5,6] The advantage of our EBL approach compared with other patterning methods is that it is a wellestablished technology within the context of nanostructure implementation, which is scalable to larger areas (i.e., bundles of many fibers), technologically flexible in terms of the actual implementation strategy, and customizable for more sophisticated material combinations.A recently introduced scheme to tailor the properties of light beams relies on metasurfaces (MSs). [7][8][9][10][11][12][13][14] These ultraflat nanoscale elements represent a promising approach to shape light fields in an unprecedented manner via managing their scattering properties. MSs are typically realized by well-established nanostructuring technologies (e.g., EBL) in combination with dry or wet etching and consist of ensembles of subwavelength scatterers with nanometer dimensions having well-controlled interelement phase relations and scattering amplitudes. By tuning the properties of the individual element, a superposition of the scattered waves of all elements of the entire ensemble-an Ansatz associated with Huygens' principle-leads to an unprecedented freedom regarding beam shaping. The operation principle of a MS can be understood on the basis of the generalized law of refraction, [7] which includes the MS by an additional phase ΔΦ that contributes to the wave passing through this surface. This phase reveals an in-plane spatial distribution ΔΦ ¼ ΔΦðx, yÞ across the area of the MS, allowing for applications such as cylindrical and spherical lenses, [10,[15][16][17] generation of orbital angular momentum states, [18][19][20] or sophisticated polarization and beam control. [21] Therefore, the combination of optical fibers with MSs represents a promising approach to

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Ultrahigh numerical aperture meta-fibre for flexible optical trapping

Cited by 110 publications

References 55 publications

Non-Diffracting Light Wave: Fundamentals and Biomedical Applications

Non-Diffracting Light Wave: Fundamentals and Biomedical Applications

Cubic-Phase Metasurface for Three-Dimensional Optical Manipulation

Plasmonic Metalens‐Enhanced Single‐Mode Fibers: A Pathway Toward Remote Light Focusing

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