Ultrafast Scan Magnetic Resonance in Prenatal Diagnosis

Wagenvoort, A.; Bekker, Mireille N.; Go, Attie T.J.I.; Vandenbussche, Frank P.H.A.; Buchem, Mark A. van; Valk, Jacob; Vugt, J.M.G. van

doi:10.1159/000021038

Cited by 63 publications

(49 citation statements)

References 22 publications

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“…The advantages of fetal MRI compared to (3-D) ultrasound are the larger field of view, superior softtissue contrast, more precise volumetric measurements and greater accuracy in the demonstration of intracranial abnormalities [17][18][19][20]. The disadvantages of MRI are that it is less readily available and its higher costs.…”

Section: Discussionmentioning

confidence: 99%

Prenatal Diagnosis of Fetal Intracranial Hemorrhage at 25 Weeks of Gestation

2003

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Objective: To determine whether magnetic resonance imaging (MRI) can give further information for the prenatal diagnosis of intracranial hemorrhage, when ultrasound (US) is not conclusive. Methods: We report on a fetus in the 26th week of gestation with a grade-III hemorrhage in the right cerebral hemisphere, which was suspected on US examination and specified by MRI examination in a patient with pre-eclampsia. Results: Doppler measurement of the umbilical artery, which showed the absence of end diastolic velocity, was indicative of placental insufficiency. The MRI specified the findings found by US examination and confirmed the poor outcome of the fetus. Labor was induced by prostaglandins in the 27th week of gestation. Postmortem examination showed a female fetus with a grade-III intracranial hemorrhage in the center of the right hemisphere with a diameter of 4 cm. A hemorrhage was also found in the subarachnoid space and in the occipital region of the left hemisphere. Conclusion: We suggest that fetuses at high risk of developing hypoxia should be sonographically evaluated and MRI should be considered when intracranial echogenicities are seen.

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Section: Discussionmentioning

confidence: 99%

Prenatal Diagnosis of Fetal Intracranial Hemorrhage at 25 Weeks of Gestation

2003

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“…Although most studies of fetal MR imaging have compared this modality with prenatal US, several studies have used confirmation with autopsy (11,12), postnatal MR imaging (13,14), or autopsy or postnatal MR imaging (3,15,16). Our study contributes to the literature by systematically comparing a large number of fetal MR examinations with postnatal MR examinations to determine the sensitivity and specificity of fetal MR imaging for specific types of brain abnormalities.…”

Section: Obstetric Imaging: Accuracy Of Fetal Mr Imaging For Corticalmentioning

confidence: 99%

Malformations of Cortical Development: Diagnostic Accuracy of Fetal MR Imaging

Glenn¹,

Cuneo²,

Barkovich³

et al. 2012

Radiology

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Purpose:To determine the diagnostic accuracy of fetal magnetic resonance (MR) imaging for malformations of cortical development by using postnatal MR imaging as reference standard. Materials and Methods:Eighty-one patients who had undergone fetal and postnatal MR imaging of the brain were identified in this institutional review board-approved, HIPAA-compliant study.Images were retrospectively reviewed in consensus by two pediatric neuroradiologists who were blinded to clinical information. Sensitivity and specificity were calculated according to retrospective review of the images and clinical reports for fetal MR images. The Fisher exact test was used to compare results for fetuses imaged before and after 24 gestational weeks and for image review versus clinical reports for fetal MR images. Results:Median gestational age at fetal MR imaging was 25.0 weeks (range, 19.71-38.14 weeks). Postnatal MR imaging depicted 13 cases of polymicrogyria, three cases of schizencephaly, and 15 cases of periventricular nodular heterotopia. Sensitivity and specificity of fetal MR imaging were 85% and 100%, respectively, for polymicrogyria; 100% each for schizencephaly; and 73% and 92%, respectively, for heterotopia. When heterotopia was seen in two planes, specificity was 100% and sensitivity was 67%. Sensitivity for heterotopia decreased to 44% for fetuses younger than 24 weeks. According to reports for fetal MR images, prospective sensitivity and specificity, respectively, were 85% and 99% for polymicrogyria, 100% and 99% for schizencephaly, and 40% and 91% for heterotopia. Conclusion:Fetal MR imaging had the highest sensitivity for polymicrogyria and schizencephaly. Specificity was 100% for all cortical malformations when the abnormality was seen in two planes. Sensitivity for heterotopia was lower for fetuses younger than 24 weeks. Knowledge of the gestational age is important, especially for counseling patients about heterotopia.q RSNA, 2012

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“…Eighty-four percent of fetuses with a ventriculomegaly diagnosis may have accompanying CNS anomalies, additive organ anomalies and chromosomal anomalies (36). In 40-50 percent of cases, associated anomalies can be shown with magnetic resonance imaging (37)(38)(39). When the ventricular width increases, the risk of additional anomalies also increases.…”

Section: Ventriculomegalymentioning

confidence: 99%

Fetal magnetic resonance imaging in obstetric practice

Köşüş

Usluoğulları

et al. 2011

J Turkish German Gynecol Assoc

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Review 39Ultrasonography (USG) is the primary imaging method for prenatal diagnosis of fetal abnormalities since its discovery. Although it is the primary method of fetal imaging, it cannot provide sufficient information about the fetus in some conditions such as maternal obesity, oligohydramnios and engagement of the fetal head. At this stage, magnetic resonance imaging (MRI) facilitates examination by providing more specific information. The need and importance of fetal MRI applications further increased by the intrauterine surgery which is currently gaining popularity.

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Ultrafast Scan Magnetic Resonance in Prenatal Diagnosis

Cited by 63 publications

References 22 publications

Prenatal Diagnosis of Fetal Intracranial Hemorrhage at 25 Weeks of Gestation

Prenatal Diagnosis of Fetal Intracranial Hemorrhage at 25 Weeks of Gestation

Malformations of Cortical Development: Diagnostic Accuracy of Fetal MR Imaging

Fetal magnetic resonance imaging in obstetric practice

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