Ultra Small, mono dispersed green synthesized silver nanoparticles using aqueous extract of Sida cordifolia plant and investigation of antibacterial activity

Pallela, Panduranga Naga Vijay Kumar; Shameem, U.; Ruddaraju, Lakshmi Kalyani; Pammi, S.V.N.; Yoon, Soon‐Gil

doi:10.1016/j.micpath.2018.08.026

Cited by 101 publications

(49 citation statements)

References 27 publications

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“…In addition, the metal ions may also produce free radicals, which could also lead to cell membrane rupture and premature cell death [37]. Antimicrobial activity is boosted by reactive oxygen species (ROS) generation and surface potential [38]. The nanoparticles could also inhibit DNA replication by binding to the phosphate moieties of DNA [39].…”

Section: Discussionmentioning

confidence: 99%

Synthesis of Gold Nanoparticles (AuNPs) Using Ricinus communis Leaf Ethanol Extract, Their Characterization, and Biological Applications

et al. 2019

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The purpose of this study was to explore the collective biological properties of Ricinus communis ethanol leaf extract (RcExt) and extract-fabricated gold nanoparticles (RcExt-AuNPs). AuNPs were synthesized using RcExt. Fingerprint data of the biochemicals putatively found in RcExt were obtained using gas chromatography–mass spectrometry (GC-MS/MS) and high-performance liquid chromatography/ultraviolet-visible (HPLC/UV-VIS) analyses. RcExt-AuNPs were characterized by UV-Vis spectroscopy, scanning electron microscopy (SEM), and Fourier- transform infrared radiation (FTIR) spectroscopy. Cytotoxic activity on the Hela and HepG2 tumor cell lines was tested through cell viability, antimicrobial activity against bacterial and fungal pathogens through a well diffusion assay, hemolytic activity on red blood cells through absorbance reading, and stimulatory/inhibitory effects on splenic cells by cell viability. AuNPs of 200 nm size were synthesized. GC-MS/MS analysis revealed 12 peaks and HPLC/UV-VIS analysis resulted in 18, 13, and five peaks at the wavelengths of 220, 254, and 300 nm, respectively. Cytotoxicity screening revealed that RcExt had stimulatory effects (6.08%) on Hela cells and an inhibitory effect (−28.33%) on HepG2 cells, whereas RcExt-AuNPs showed inhibitory effects (−58.64% and −42.74%) on Hela and HepG2 cells, respectively. Antimicrobial activity of RcExt-AuNPs against tested pathogens was significantly higher (average diameters of inhibition zones were higher (ranging from 9.33 mm to 16.33 mm)) than those of RcExt (ranging from 6.00 mm to 7.33 mm). RcExt and RcExt-AuNPs showed 4.15% and 100% lytic effects, respectively. Inhibitory effects on splenic cells for RcExt-AuNPs were observed to be significantly higher (−30.56% to −72.62%) than those of RcExt (−41.55% to −62.25%) between concentrations of 25 to 200 µg/mL. RcExt-AuNPs were inhibitory against HepG2 and Hela cells, while RcExt inhibited HepG2 but stimulated Hela cells. RcExt-AuNPs showed comparatively more antimicrobial activity. RcExt was safe while RcExt-AuNPs harmful to red blood cells (RBCs). RcExt and RcExt-AuNPs showed inhibitory effects on splenic cells irrespective of dose.

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Section: Discussionmentioning

confidence: 99%

Synthesis of Gold Nanoparticles (AuNPs) Using Ricinus communis Leaf Ethanol Extract, Their Characterization, and Biological Applications

et al. 2019

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“…The ultra-small size of nanoparticles was responsible for deep penetration and AuNPs diffused through the cell membrane of microbial pathogens and disrupted the cell function causing cell death. Further, antimicrobial activity was also boosted by reactive oxygen species (ROS) generation and surface potential [30]. Previously, many types and sizes nanoparticles have been effectively used to induce the delivery of therapeutic agents [22,31] to cure infections in skin [32].…”

Section: Discussionmentioning

confidence: 99%

Biological Activities of Euphorbia peplus Leaves Ethanolic Extract and the Extract Fabricated Gold Nanoparticles (AuNPs)

2019

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Euphorbia peplus leaves extract (EpExt) and gold nanoparticles (AuNPs) phytofabricated with extract (EpExt-AuNPs) were investigated for biological activities. EpExt and EpExt-AuNPs were screened for: (i) anticancer activity against Hela and HepG2 cell lines; (ii) antimicrobial activity; (iii) hemolytic activity; (iv) cytotoxic or stimulatory effects; and (v) insecticidal activity. AuNPs (size 50 nm) were synthesized. (i) EpExt had a stimulatory effect (51.04%) on Hela cells and an inhibitory effect (−12.83%) on HepG2 cells while EpExt-AuNPs showed inhibitory effects (−54.25% and −59.64% on Hela and HepG2 cells respectively). (ii) Antimicrobial activity of EpExt-AuNPs was significantly higher (ranged from 11.67 mm to 14.33 mm) than that of EpExt (ranged from 5.33 mm to 6.33 mm). (iii) Both EpExt and EpExt-AuNPs displayed 100% hemolysis. (iv) A dose-dependent inhibitory effect of EpExt was observed (ranged from −48.5% to −92.1%), which was greater than that of EpExt-AuNPs (ranged from −32.1% to −69.1%) (v) EpExt-AuNPs was more lethal against mosquito larvae with lethal concentration (LC50) value (202.692 ppm) compared to EpExt (1430.590 ppm). In conclusion, EpExt-AuNPs were inhibitory against HepG2 and Hela cells, while EpExt inhibited HepG2 but stimulated Hela cells. EpExt-AuNPs had antimicrobial effects. EpExt showed dose-dependent inhibitory effects on splenic cells. EpExt-AuNPs were lethal against mosquito larvae.

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“…MNPs and MONPs produced by green synthesis using plants have various activities such as antibacterial [88,89], antifungal [12], anticancer [90], and larvicidal [91].…”

Section: Beet For Green Synthesis Of Mnpsmentioning

confidence: 99%

“…The qualification and velocity of the green synthesis of MNPs and MONPs sympathize the model lineaments of the traditional chemical synthesis. Controlling MNPs and MONPs synthesis factor variation is very important to produce MNPs and MONPs with demanding properties and provide background on consistent mechanism [88,89,92]. The green synthesis of MNPs and MONPs happens in the plant in vivo [93,94].…”

Section: Beet For Green Synthesis Of Mnpsmentioning

confidence: 99%

Green synthesis of metal and metal oxide nanoparticles from plant leaf extracts and their applications: A review

Shafey

2020

Green Processing and Synthesis

450

161

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AbstractMetal nanoparticles (MNPs) and metal oxide nanoparticles (MONPs) are used in numerous fields. The new nano-based entities are being strongly generated and incorporated into everyday personal care products, cosmetics, medicines, drug delivery, and clothing to impact industrial and manufacturing sectors, which means that nanomaterials commercialization and nano-assisted device will continuously grow. They can be prepared by many methods such as green synthesis and the conventional chemical synthesis methods. Green synthesis includes infinite accession to produce MNPs and MONPs with demanding properties. The structure–function relationships between nanomaterials and key information for life cycle evaluation lead to the production of high execution nanoscale materials that are gentle and environmentally friendly. Majority of plants have features as sustainable and renewable suppliers compared with microbes and enzymes, as they have the ability to pick up almost 75% of the light energy and transform it into chemical energy, contain chemicals like antioxidants and sugars, and play fundamental roles in the manufacture of nanoparticles. Plants considered the main factory for the green synthesis of MNPs and MONPs, and until now, different plant species have been used to study this, but the determined conditions should be taken into consideration to execute this preparation. In this study, we focus on the biosynthesis procedures to synthesize MNPs and MONPs, including comparison between green synthesis and the classical chemistry methods as well as the several new orientation of green synthesis of nanoparticles from different plant parts, especially plant leaf extracts. Plants with reducing compounds is the preferred choice for the synthesis of noble metals – metal ions can be reduced to the corresponding metals in the absence of any other chemicals under microwave irradiation conditions using benign solvent, water. Noble metals such as gold (Au), silver (Ag), platinum (Pt), and palladium (Pd) and other metals such as copper (Cu) and nickel (Ni), which are characterized by their optical, electronic, mechanical, magnetic, and chemical properties, leading to different technological applications. Plants with numerous reducing agents are suitable candidates for the manufacture of noble MNPs. The main purpose of this research is to give a background on green nanotechnology prospective evolution, pertinent concerns appeared related to the green synthesis of metal and metal oxide from plant extracts, nanoparticle formation mechanism, and the importance of flavonoids, vitamin B2, ascorbic acid (vitamin C), and phenolic compounds in the MNP and MONP production. The traditional sorghum beers are produced in many countries in Africa, but diversity in the production process may depend on the geographic localization. These beers are very rich in calories; B-group vitamins including thiamine, folic acid, riboflavin, and nicotinic acid; and essential amino acids such as lysine. However, the Western beers are more attractive than the traditional sorghum beers. The traditional sorghum beers have poor hygienic quality, organoleptic variations, and shorter shelf life compared with the Western beers. Many research studies on traditional sorghum beers have been carried out and documented in several African countries, especially the microbiological and biochemical properties, the technologies used in the manufacture processes, and synthetic characteristics of African traditional sorghum beers (ikigage, merissa, doro, dolo, pito, amgba, and tchoukoutou). The excellent resources for the production of greener biomaterials are plants and considerable advances have been achieved in many fields such as biotechnology and gene transfer. The manufactured biological nanomaterials have a great application in the pharmaceutical industry such as novel pharmaceuticals preparation, drug delivery personification procedures, and production of functional nanodevices.

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Ultra Small, mono dispersed green synthesized silver nanoparticles using aqueous extract of Sida cordifolia plant and investigation of antibacterial activity

Cited by 101 publications

References 27 publications

Synthesis of Gold Nanoparticles (AuNPs) Using Ricinus communis Leaf Ethanol Extract, Their Characterization, and Biological Applications

Synthesis of Gold Nanoparticles (AuNPs) Using Ricinus communis Leaf Ethanol Extract, Their Characterization, and Biological Applications

Biological Activities of Euphorbia peplus Leaves Ethanolic Extract and the Extract Fabricated Gold Nanoparticles (AuNPs)

Green synthesis of metal and metal oxide nanoparticles from plant leaf extracts and their applications: A review

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