Ultra-sensitive and label-free neutrophil gelatinase-associated lipocalin electrochemical sensor using gold nanoparticles decorated 3D Graphene foam towards acute kidney injury detection

Danvirutai, Pobporn; Ekpanyapong, Mongkol; Tuantranont, Adisorn; Bohez, Erik L. J.; Anutrakulchai, Sirirat; Wisitsoraat, Anurat; Srichan, Chavis

doi:10.1016/j.sbsr.2020.100380

Cited by 19 publications

(15 citation statements)

References 22 publications

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“…Wearable and implantable sensors can monitor various human health indicators and offer insight into kidney, cardiovascular, and respiratory system diseases. These technologies help facilitate early prevention and proper treatment [ 14 , 15 , 16 ].…”

Section: Introductionmentioning

confidence: 99%

Applications of Transistor-Based Biochemical Sensors

Gao

Ming

2023

Biosensors

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Transistor-based biochemical sensors feature easy integration with electronic circuits and non-invasive real-time detection. They have been widely used in intelligent wearable devices, electronic skins, and biological analyses and have shown broad application prospects in intelligent medical detection. Field-effect transistor (FET) sensors have high sensitivity, reasonable specificity, rapid response, and portability and provide unique signal amplification during biochemical detection. Organic field-effect transistor (OFET) sensors are lightweight, flexible, foldable, and biocompatible with wearable devices. Organic electrochemical transistor (OECT) sensors convert biological signals in body fluids into electrical signals for artificial intelligence analysis. In addition to biochemical markers in body fluids, electrophysiology indicators such as electrocardiogram (ECG) signals and body temperature can also cause changes in the current or voltage of transistor-based biochemical sensors. When modified with sensitive substances, sensors can detect specific analytes, improve sensitivity, broaden the detection range, and reduce the limit of detection (LoD). In this review, we introduce three kinds of transistor-based biochemical sensors: FET, OFET, and OECT. We also discuss the fabrication processes for transistor sources, drains, and gates. Furthermore, we demonstrated three sensor types for body fluid biomarkers, electrophysiology signals, and development trends. Transistor-based biochemical sensors exhibit excellent potential in multi-mode intelligent analysis and are good candidates for the next generation of intelligent point-of-care testing (iPOCT).

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Section: Introductionmentioning

confidence: 99%

Applications of Transistor-Based Biochemical Sensors

Gao

Ming

2023

Biosensors

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“…In this work, we aimed to develop a low-cost and highly sensitive electrochemical sensor composed of three-dimensional graphene foam (GF) and composite ferrous-carbon nanoflowers (GNF)—the electrode material was then abbreviated as GF/GNFs—to determine arsenic levels in the water. Earlier, the GF/Ni-based electrochemical sensor was revealed to have ultra-high sensitivity [ 15 , 16 ]. Additionally, a three-dimensional GF with nanoscale decorations has been reported as ideal for the development of several sensors.…”

Section: Introductionmentioning

confidence: 99%

Nanoflowers on Microporous Graphene Electrodes as a Highly Sensitive and Low-Cost As(III) Electrochemical Sensor for Water Quality Monitoring

Kosuvun

Danvirutai

Hormdee

et al. 2023

Sensors

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In this work, we report a low-cost and highly sensitive electrochemical sensor for detecting As(III) in water. The sensor uses a 3D microporous graphene electrode with nanoflowers, which enriches the reactive surface area and thus enhances its sensitivity. The detection range achieved was 1–50 ppb, meeting the US-EPA cutoff criteria of 10 ppb. The sensor works by trapping As(III) ions using the interlayer dipole between Ni and graphene, reducing As(III), and transferring electrons to the nanoflowers. The nanoflowers then exchange charges with the graphene layer, producing a measurable current. Interference by other ions, such as Pb(II) and Cd(II), was found to be negligible. The proposed method has potential for use as a portable field sensor for monitoring water quality to control hazardous As(III) in human life.

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“…Apart from zero-, one-and twodimensional graphene structures, three-dimensional microporous Graphene Foam (GF) was successfully fabricated during 2010s 1 .. Afterwards, wide applications of GF were reported from supercapacitors 2 , field-effect transistors 3 , electrochemical sensors [4][5] and Surface-Enhanced Raman Scattering (SERS) substrate [6][7] . In theoretical point of view, the study of electronic transport in graphene-based materials could triggered the on-going progress of physics of this two-dimensional material [8][9] .…”

Section: Introductionmentioning

confidence: 99%

“…Before we come across the quantization at room temperature of three-dimensional microporous graphene, brief experimental setup will be described as follows. At the first place, we focus on decorating noble metallic nanoparticles on three-dimensional microporous graphene to be applied as SERS substrate [6][7] and highly sensitive electrodes [4][5] . We planned to deposit nanoparticles of noble metals (AuNPs and AgNPs) on the graphene foam surface using electrochemical method, for the purpose of enhancing sensing capability.…”

Section: Introductionmentioning

confidence: 99%

Quantum Hall-like effect in electrochemical systems due to extra-dimension embedded in 3D graphene at room temperature

Sric

Danvirutai²,

Wisitsoraat

et al. 2022

Preprint

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In this work, we report for the first time, the quantization effect occurred at room temperature in an electrochemical system. The setup where it occurred was electrodeposition of gold nanoparticles (AuNPs) and silver nanoparticles (AgNPs) onto three-dimensional microstructure graphene (GF) under certain applied potential. This is the first time that this quantum phenomenon occurs in solutions under electrochemical experiment. This effect might be described as quantum coherency in extra dimension embedded in three-dimensional microstructure of graphene foam which approximately hold radius around 100 µm. Possible explanation was proposed that the quantum effect occurs due to quantization in extra dimension when certain conditions were met. Our simplified quantum calculation could be used to fit with the experimental data. The quantization behaviors were observed in both silver and gold electrodeposition on GF. Primary theoretical description was explained in this article using Landauer formalism and Polyakov action from string theory. However, the concrete theoretical explanation could possibly be further elaborated or explained in a different way (Supplementary data contains the experimented videos).

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Ultra-sensitive and label-free neutrophil gelatinase-associated lipocalin electrochemical sensor using gold nanoparticles decorated 3D Graphene foam towards acute kidney injury detection

Cited by 19 publications

References 22 publications

Applications of Transistor-Based Biochemical Sensors

Applications of Transistor-Based Biochemical Sensors

Nanoflowers on Microporous Graphene Electrodes as a Highly Sensitive and Low-Cost As(III) Electrochemical Sensor for Water Quality Monitoring

Quantum Hall-like effect in electrochemical systems due to extra-dimension embedded in 3D graphene at room temperature

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