Ultra-Performance Liquid Chromatography with Electrospray Ionization Tandem Mass Spectrometry for the Determination of Ketoconazole in Anti-Dandruff Shampoo

Kim, So Hyun; Shrestha, Anil; Hoang, Nguyen Huu; Hương, Nguyễn Lan; Park, Je Won

doi:10.1080/00032719.2013.874013

Cited by 3 publications

(2 citation statements)

References 17 publications

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“…Determination of ketoconazole due to its importance in biological fluids, pharmaceutical preparations, and also cosmetic products appears to be worthwhile. Various methods have been developed for this purpose, including spectrophotometry, [4][5][6][7] high-performance liquid chromatography, [8][9][10] and liquid chromatography-triple quadrupole tandem mass spectrometry. 11 These methods are often time-consuming and require expensive equipment.…”

Section: Ketoconazole Is 1-acetyl-4-[4-[[2rs4sr)-2-(24-dichlorophenmentioning

confidence: 99%

Low-level Electrochemical Analysis of Ketoconazole by Sepiolite Nanoparticles Modified Sensor in Shampoo Sample

Aydar

Bayraktepe

Filik

et al. 2020

ACSi

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In this study, the nano-sepiolite modified carbon paste electrode (CCPE) was prepared for the determination of ketoconazole (KC). The effects of pH, the proportion of the electrode modifier, deposition potential, and deposition time were investigated. Ketoconazole shows one irreversible oxidation peak at about the potential value of 0.6-0.7 V at different pH values. CV studies show that the modified electrode performed a catalytic effect on the peak signal of KC compared to the bare electrode. This catalytic behavior of CCPE was used for the development of a sensitive detection method. The impact of pH and scan rates on the anodic peak potentials and currents were examined, and the scan rate results show that the oxidation behavior of KC was controlled by the adsorption process at the CCPE surface. Therefore, adsorptive stripping differential pulse voltammetry (AdsDPV) and adsorptive stripping square wave voltammetry (AdsSWV) methods were developed for KC analysis. The two different linear ranges were obtained as (0.1−1.0) nM and (3.

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Section: Ketoconazole Is 1-acetyl-4-[4-[[2rs4sr)-2-(24-dichlorophenmentioning

confidence: 99%

Low-level Electrochemical Analysis of Ketoconazole by Sepiolite Nanoparticles Modified Sensor in Shampoo Sample

Aydar

Bayraktepe

Filik

et al. 2020

ACSi

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“…From an analytical chemistry point of view, hair care products are considered to be complicated matrices containing numerous organic and inorganic compounds, thus requiring extra sample cleanup steps prior to the end-point analysis. Representative recent analytical applications in hair care products are presented in Table 1 [ 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 ]. As can be seen in the examples of Table 1 , solid- or liquid-phase extraction steps are quite common even when sophisticated LC-MS instrumentation is employed, while dry ashing/wet digestion are necessary for the determination of inorganic analytes.…”

Section: Introductionmentioning

confidence: 99%

Determination of Free Histidine in Complex Hair Care Products with Minimum Sample Preparation Using Cation-Exchange Chromatography and Post Column Derivatization

Tsiasioti

Zacharis²,

Tzanavaras³

2023

Molecules

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In this communication, we describe the first analytical method for the determination of free histidine in hair care products (shampoos and conditioners). Cation-exchange chromatography combined with postcolumn derivatization and fluorimetric detection enabled the accurate (recovery: 83.5–114.8%) and precise (2.4–5.6% RSD) determination of free histidine without matrix interferences at concentration levels down to 1.5 mg kg−1. Real commercially available samples were found to contain the amino acid at levels ranging between 70 and 535 mg kg−1.

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Unique green chromatographic method for the qualitative and quantitative analysis of ketoconazole, its impurities and preservatives from ketoconazole cream formulation: Identification of degradants by Q-ToF LCMS and Robustness by Design of Experiments

Muchakayala,

Katari,

Saripella

et al. 2023

Sustainable Chemistry and Pharmacy

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Ultra-Performance Liquid Chromatography with Electrospray Ionization Tandem Mass Spectrometry for the Determination of Ketoconazole in Anti-Dandruff Shampoo

Cited by 3 publications

References 17 publications

Low-level Electrochemical Analysis of Ketoconazole by Sepiolite Nanoparticles Modified Sensor in Shampoo Sample

Low-level Electrochemical Analysis of Ketoconazole by Sepiolite Nanoparticles Modified Sensor in Shampoo Sample

Determination of Free Histidine in Complex Hair Care Products with Minimum Sample Preparation Using Cation-Exchange Chromatography and Post Column Derivatization

Unique green chromatographic method for the qualitative and quantitative analysis of ketoconazole, its impurities and preservatives from ketoconazole cream formulation: Identification of degradants by Q-ToF LCMS and Robustness by Design of Experiments

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