UJI DAYA ANTIMIKROBA EKSTRAK ETANOL DAUN SIRIH MERAH (Piper Crocatum Ruiz &amp; Pav.) TERHADAP PERTUMBUHAN Staphylococcus aureus ATCC 6538, Eschericia coli ATCC 11229 DAN Candida albicans ATCC 10231 SECARA IN VITRO

Candrasari, Anika; Romas, M. Amin; Astuti, Ovi Rizky

doi:10.23917/biomedika.v4i1.258

Cited by 24 publications

(23 citation statements)

References 2 publications

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“…Diketahui bahwa daun sirih merah mengandung senyawa-senyawa antibakteri seperti flavonoid, alkaloid senyawa polifenol, tanin dan minyak atsiri (Puspita et al, 2018). Flavonoid, alkaloid, tanin dan minyak atsiri pada daun sirih merah berfungsi sebagai zat aktif antibakteri diantaranya Staphylococcus aureus, Escherichia coli, dan Candida albicans (Candrasari et al, 2012). Selain itu secara empiris zat aktif tersebut juga memiliki efek mencegah ejakulasi dini, antikejang, membasmi kuman, penghilang rasa nyeri dan menghilangkan bengkak, mengatasi radang paru, radang tenggorokan, gusi bengkak, radang payudara, hidung mimisan, kencing manis, ambeien, jantung koroner, darah tinggi, asam urat, dan batuk berdarah (Hermiati et al, 2013).…”

Section: Pendahuluanunclassified

Peningkatan Pengetahuan tentang Pencegahan Infeksi dan Penyebaran Penularan COVID-19 di Panti Asuhan/LKSA Darul Tazkiyah Kota Palangka Raya

Purbayanti

Ardina

Suryadini

2021

Pengabdianmu J Ilmiah Pengabdian Masyarakat

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COVID-19 infection regardless of age. It can infect children, adults, and older adults. Children and older adults are high-risk groups of infection. An orphanage where many children live in one place with a high risk of transmission of the SARS-CoV-2 virus. Education about prevention of infection and the spread of COVID-19 transmission at Darul Tazkiyah orphanage Palangka Raya was needed. The implementation methods included a pre-test, education about COVID-19, post-test, and submission of calendars containing information on prevention of COVID-19, posters, betel leaf extract hand sanitizers and health protocols banners. A total of 46 orphanage children became respondents. The paired sample t-test showed that p-value (0.000) <0.05. It meant there was a difference between pre-test and post-test results, which meant there was an increasing children's knowledge about prevention of infection and the spread of COVID-19 transmission at Darul Tazkiyah Orphanage, Palangka Raya. Based on the results of the service activities carried out, it showed that providing education can increase children's knowledge about how efforts to prevent transmission of COVID-19, so it is hoped that this increased knowledge can minimize transmission of COVID-19 and help government programs to reduce positive cases of COVID-19 in Palangka Raya in particular.

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Section: Pendahuluanunclassified

Peningkatan Pengetahuan tentang Pencegahan Infeksi dan Penyebaran Penularan COVID-19 di Panti Asuhan/LKSA Darul Tazkiyah Kota Palangka Raya

Purbayanti

Ardina

Suryadini

2021

Pengabdianmu J Ilmiah Pengabdian Masyarakat

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“…The phytochemicals contained in P. crocatum were alkaloids, flavonoid, glycoside, saponin, tannin, and triterpenoid [12]. There were only limited studies about P. crocatum , its chemical constituents and activity as an antibacterial agent.…”

Section: Discussionmentioning

confidence: 99%

Combination Effect of Antituberculosis Drugs and Ethanolic Extract of Selected Medicinal Plants against Multi-Drug Resistant Mycobacterium tuberculosis Isolates

2017

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Adverse drug reaction and resistance to antituberculosis drugs remain the causes of tuberculosis therapeutic failure. This research aimed to find the combination effect of standard antituberculosis drugs with Hibiscus sabdariffa L., Kaempferia galanga L., and Piper crocatum N.E. Br against multi-drug resistant (MDR) Mycobacterium tuberculosis isolates. Two MDR strains (i.e., isoniazid/ethambutol resistant and rifampicin/streptomycin resistant) of M. tuberculosis were inoculated in Löwenstein–Jensen medium containing a combination of standard antituberculosis drugs and ethanolic extracts of H. sabdariffa calyces, K. galanga rhizomes, and P. crocatum leaves using various concentration combinations of drug and extract. The colony numbers were observed for 8 weeks. The effect of the combination was analyzed using the proportion method which was calculated by the mean percentage of inhibition reduction in a number of colonies on drug–extract containing medium compared to extract-free control medium. The results showed that all three plant extracts achieved good combination effects with rifampicin against the rifampicin/streptomycin resistant strain. Antagonistic effects were, however, observed with streptomycin, ethambutol and isoniazid, therefore calling for caution when using these plants in combination with antituberculosis treatment.

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“…This means that the higher of D. salina crude extract, the more the inhibitory activity against E. tarda. The smallest or largest of the inhibition zone is also influenced by several factors including the toxicity of the test material, the diffusion ability of the test material in the media, the interaction between media components, and the in vitro microenvironment conditions (Candrasari et al, 2012).…”

Section: Antimicrobial Testmentioning

confidence: 99%

Minimum Inhibitory Concentration of Marine Microalgae Dunaliella salina on Fish Pathogenic Bacteria Edwardsiella tarda

Rusmawanto

Prajitno

Yuniarti

2019

RJLS

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Dunaliella salina is a type of marine microalgae. The objective of this research were investigated the effect of D. salina to inhibit the growth of E. tarda. The method used in this study was examined antibacterial activity of D. salina using disc diffusion and co culture test. The secondary metabolite compound in D. salina was tested using phytochemical screening and FTIR methods. The results obtained D. salina extracted using n-hexane showed the best activity for inhibiting the growth of E. tarda. Minimum concentration of 100 mg.L -1 crude extract can inhibit E. tarda with a total of bacterial colonies 137x10 11 CFU.mL -1 . The phytochemical test results showed that D. salina extract using n-hexane contained flavonoids, saponins, alkaloids, terpenoids and phenols. The FTIR analysis showed phenol and carotene compounds are one of the secondary metabolites that can be used as antibacterial. It can be concluded that the extract has strong antibacterial activity against E. tarda and potentially as antibacterial in aquaculture.

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UJI DAYA ANTIMIKROBA EKSTRAK ETANOL DAUN SIRIH MERAH (Piper Crocatum Ruiz & Pav.) TERHADAP PERTUMBUHAN Staphylococcus aureus ATCC 6538, Eschericia coli ATCC 11229 DAN Candida albicans ATCC 10231 SECARA IN VITRO

Cited by 24 publications

References 2 publications

Peningkatan Pengetahuan tentang Pencegahan Infeksi dan Penyebaran Penularan COVID-19 di Panti Asuhan/LKSA Darul Tazkiyah Kota Palangka Raya

Peningkatan Pengetahuan tentang Pencegahan Infeksi dan Penyebaran Penularan COVID-19 di Panti Asuhan/LKSA Darul Tazkiyah Kota Palangka Raya

Combination Effect of Antituberculosis Drugs and Ethanolic Extract of Selected Medicinal Plants against Multi-Drug Resistant Mycobacterium tuberculosis Isolates

Minimum Inhibitory Concentration of Marine Microalgae Dunaliella salina on Fish Pathogenic Bacteria Edwardsiella tarda

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