Uber Arthropoden-Abwehrstoffe XXXVI

Abstract

Die Käfer der Insektengattung Ilybius besitzen, wie die meisten der bisher untersuchten Arten der Familie Dytiscidae (Schwimmkäfer), im Prothorax gelegene, paarig angeordnete Komplexdrüsen. Diese Drüsen produzieren und speichern ein aus mehreren Komponenten bestehendes, schwach gelbes Wehrsekret, dessen Hauptkomponente durch Gelchromatographie an Sephadex LH-20 isoliert und durch eine Elektronenbrenzanalyse sowie durch Anwendung spektroskopischer Methoden als 8-Hydroxychinolincarbonsäure-2-methylester identifiziert wurde.

Biosynthesis of 8-hydroxyquinoline-2-carboxylic acid, an iron chelator from the gut of the lepidopteran Spodoptera littoralis

“…1 Xanthurenic acid (4,8-dihydroxyquinoline-2-carboxylic acid) was found in Drosophila melanogaster 2,3 and several mosquito species. 1 Xanthurenic acid (4,8-dihydroxyquinoline-2-carboxylic acid) was found in Drosophila melanogaster 2,3 and several mosquito species.…”

“…Methyl-8-hydroxyquinoline-2-carboxylate was isolated by H. Schildknecht from the defensive secretion of the water beetle Ilybius fenestratus. 1 Xanthurenic acid (4,8-dihydroxyquinoline-2-carboxylic acid) was found in Drosophila melanogaster 2,3 and several mosquito species. 4,5 Elucidation of its biosynthetic pathway showed that it derives from tryptophan and is formed via 3-hydroxykynurenine [5][6][7] (Scheme 1).…”

Biosynthesis of Quinoline by a Stick Insect

“…About a century later, Späth and Pikl reported it as one of the trace constituents (about 0.003%) of angostura bark ( Cusparia trifoliata ). Many compounds that have a quinoline-core structure such as quinine and chloroquine are used as active ingredients in pharmaceutical preparations. , Although many quinoline-based alkaloids are known from plants, animals, and microbial sources, − unsubstituted quinoline as an animal natural product has been identified only from O . peruana …”

Caelestines A−D, Brominated Quinolinecarboxylic Acids from the Australian Ascidian Aplidium caelestis

“…ABSTRACT: Four new brominated natural products, caelestines A−D (1)(2)(3)(4), have been isolated from the Australian ascidian Aplidium caelestis. The structures of 1-4 were determined by analysis of their NMR and MS data.…”