Über 1.2.4‐Triazole, I Die Reaktion von Thiocarbohydrazid und Thiosemicarbazid mit aliphatischen Carbonsäuren und ihren Derivaten

Abstract

Die Kondensation von Thiocarbohydrazid mit aliphatischen Carbonsäuren oder deren Orthoestern liefert 3‐Alkyl‐4‐amino‐5‐mercapto‐1.2.4‐triazole. Salpetrige Säure desaminiert diese Verbindungen zu 3‐Alkyl‐5‐mercapto‐1.2.4‐triazolen, die auch durch alkalische Cyclisierung der aus Thiosemicarbazid und Carbonsäuren zugänglichen 1‐Acyl‐thiosemicarbazide entstehen. Der Ringschluß von Thiocarbohydrazid bzw. Thiosemicarbazid mit Formamid ergibt ebenfalls die Stammsubstanzen der beiden Verbindungsreihen. — Die schon von P. C. GUHA und S. C. De untersuchte Reaktion von Thiocarbohydrazid mit Acetanhydrid wird in ihrem Verlauf aufgeklärt.

Synthesis of bicyclo[3.3.1]nonane derivatives containing fused heterocyclic rings

“…Compounds 2-4 bearing two heterocyclic rings were synthesized by the condensation of 3,7-dichlorbicyclo[3.3.1]nonan-2,6-dione (1) (racemate) [9][10][11] with 4-amino-2,4-dihydro-3H-triazolothione 12 , 2-thiobenzimidazole and thiocarbamide (Scheme 1). …”

Synthesis of Ag(I) and Cu(I) Complexes with 4-Amino-5-Methyl-2h-1,2,4-Triazole-3(4h)-Thione Ligand as Thiocarbohydrazide Derivatives and their Antimicrobial Activity

“…4-Amino-5-methyl-2H-1,2,4-triazole-3(4H)-thione (AMTT) was prepared according to reported procedures [16] and [Ag(AMTT) 2 ]NO 3 and [Cu(AMTT)] n Cl n complexes were synthesized according to literature [14,15].…”

Heteropolyacides as green and reusable catalysts for the synthesis of [3,4-<i>b</i>][1,3,4] thiadiazines

“…The chemicals used in this work were purchased from Fluka (Buchs, Switzerland) and were used without further purification. Heteroployacids (HPAs) were prepared as previously described in the literature [41,42] and also the compounds AMTTO and AMTT was prepared as previously described in the literature [43][44][45].…”