U-shaped relationship between nocturnal blood pressure and organ impairment

Continuous non-invasive determination of nocturnal blood pressure variation using photoplethysmographic pulse wave signals: comparison of pulse propagation time, pulse transit time and RR-interval

“…The 'Dublin Outcome Study' with 5292 untreated hypertensive patients referred to a single BP clinic shows that (1) nocturnal ambulatory BP is the most potent predictor for cardiovascular risk followed by (2) 24 h ambulatory BP measurement (ABPM), (3) daytime ambulatory BP measurement, and (4) clinical BP measurement (Dolan et al 2005). Therefore, due to its significantly increased morbidity and mortality, a missed lowering in the nocturnal BP has a diagnostic and prognostic value as well as therapeutic consequences (Dolan et al 2005, Middeke 2005).…”