Typhoid Fever and Cochleovestibular Lesions

Abstract

Six cases of pathologically confirmed cochleovestibular lesions due to typhoid fever are presented- The lesions occurred between the second and third weeks of the disease (5 of 6 cases), in the left ear more commonly than in the right (4 of 6 cases), and in females more often than in males (5 of 6 cases). Some of the lesions were reversible. Factors believed to be significant for development of these lesions include host susceptibility, endotoxins, arteritis, and ischemia.

Acute sensorineural hearing loss in a child with typhoid fever

“…1,2 Only a few cases have been described in children. [1][2][3][4] The hearing loss usually occurs from second to third week of illness, and may occasionally become permanent.…”

“…1,2 Only a few cases have been described in children. [1][2][3][4] The hearing loss usually occurs from second to third week of illness, and may occasionally become permanent. 2,3 In our patient, hearing loss appeared on day 13, started showing improvement from day 21, and recovered completely by day 44 of illness.…”

“…[1][2][3][4] The hearing loss usually occurs from second to third week of illness, and may occasionally become permanent. 2,3 In our patient, hearing loss appeared on day 13, started showing improvement from day 21, and recovered completely by day 44 of illness. Similar hearing loss is reported more commonly in our country in patients with scrub typhus, which we excluded by serological tests.…”

“…In a study of six cases of pathologically confirmed cochleovestibular lesions due to typhoid fever, host susceptibility, endotoxins, arteritis, and ischemia were the factors believed to have resulted in development of these lesions and the consequent hearing loss. 2 Cochleo-vestibulitis may also occur secondary to endotoxinemia and cytokine mediated damage. 7 The treatment of SNHL in typhoid fever involves effective antibiotic therapy for the infection.…”

“…1 Of all the atypical features of enteric fever, cochleovestibular involvement resulting in sensorineural hearing loss (SNHL) has been reported rarely in children as well as adults. 2 Most patients show complete recovery after effective antibiotics use, but permanent loss of hearing has also been reported. 3 It is important to recognize SNHL as a complication of enteric fever to prevent delays in clinical suspicion of disease that often happens when patients present with atypical manifestations.…”