Type Incidence of Herpes Simplex Virus in Clinical Isolates from Patients with Herpes Genitalis

Al-Samarai, A; Shareef, Anisa Abd Ul-Habib; Kinghorn, G R; Potter, C. W.

doi:10.5144/0256-4947.1990.156

Cited by 5 publications

(8 citation statements)

References 18 publications

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“…Primary genital infections may be caused by types 1 or 2, although HSV 2 infections are most likely to cause genital recurrences. 18 Previous studies have shown that concurrent oral and genital infections with an identical HSV strain may occur in the same person and that prior oral herpes caused by HSV 1 fails to prevent subsequent genital infection with HSV 2. Nevertheless, exogenous reinfection with either HSV 1 or HSV 2 in patients with recurrent genital herpes is considered to be uncommon.…”

Section: Discussionmentioning

confidence: 99%

Risk factors for bad obstetric history in Kirkuk women, Iraq

Aljumaily

2013

Int J Infection & Microbiol

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INTRODUCTION: Microbial agents such as Toxoplasma, rubella, CMV and HSV are important cause of infections during pregnancy, which mainly are asymptomatic. However, the infection during pregnancy may result in serious foetal side effects. Objective was to determine the risk factors that enhance the development of bad obstetric history (BOH) due to TORCH infections in Iraqi women. MATERIALS AND METHODS: A 538 women were included in the study, of them 293 (54.5%) were with BOH, and 245 (45.5%) were with normal pregnancy history. In the BOH group, 144 (49.1%) women were pregnant, while in the normal pregnancy group, 117 (47.7%) were pregnant. Logistic regression analysis was used to determine the risk factors that may play a role in development of BOH. RESULTS: Multifactorial analysis indicated that Toxoplasma gondi IgM, rubella IgM, rubella IgG, CMV IgM, HSV -2 IgG and animal exposure were risk factors that lead to BOH development. However, Toxoplasma IgG seropositivity had inverse correlation to BOH development. Mother education was a significant protective (OR=0.614, P=0.000) factor that reduce development of BOH. Residence, education, occupation and family size influenced the role of TORCH in induction of BOH. CONCLUSIONS: This study indicated that Toxoplasma gondi IgM, rubella IgM, rubella IgG, CMV IgM, HSV-2 IgG and animal exposure were risk factors that lead to BOH development. Mother education was a significant protective factor that reduce development of BOH. DOI: http://dx.doi.org/10.3126/ijim.v2i3.8121 Int J Infect Microbiol 2013;2(3):70-77

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Section: Discussionmentioning

confidence: 99%

Risk factors for bad obstetric history in Kirkuk women, Iraq

Aljumaily

2013

Int J Infection & Microbiol

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“…Herpes simplex virus (HSV) infections are caused by two strains, HSV-1 and HSV-2. Orolabial infection is mainly caused by HSV-1, however, this strain is responsible for up to 53% of primary genital herpetic infection [3]. HSV-2 genital infection is much more likely to recur than genital HSV-1 infection, thus the presence of antibody to HSV-2 and a compatible clinical history would be strong presumptive evidence that the disease is recurrent genital herpes [4][5][6].…”

Section: Introductionmentioning

confidence: 99%

Association between Herpes Simplex virus type 2 (HSV 2) and bad obstetric outcomes

Hassan¹,

Alsamarai²,

Aljumaili³

et al. 2014

Our Dermatol Online

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Introduction: HSV is a common human pathogen that lead to lifelong latent infection. Maternal infections may be associate with transmission to the fetus. The risk factors associated with HSV 2 seropositivity in pregnant women in Iraq are not well studied. Aim: The present study conducted to verify the prevalence of HSV 2 infections in women with bad obstetric history (BOH) in Kirkuk Governorate. Material and Methods: HSV 2 seropositivity among women aged 14 to 48 years was investigated by determination of HSV 2 IgG and IgM in a prospective, case control descriptive study. Results: The overall HSV 2 seroprevalence was 29.9%, with a non significant difference between women with BOH and women with normal pregnancy. HSV 2 IgM, as an indicator of current infection was demonstrated in 2% of the studied population, and was significantly (P= 0.002) higher in women with BOH compared to women with normal pregnancy. Both HSV 2 IgG and IgM were significantly varied with age groups, with trends of increasing with older ages. HSV 2 IgG was statistically significantly higher in working women (P=0.03) as compared to housewife. Conclusions: Significant association was found between HSV 2 seroprevalence and education levels, residence, smoking and animal exposure. Presence of pregnancy in women with HSV-2 latent infection was a risk factor for development of BOH.

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“…Herpes simplex virus (HSV) is an ubiquitous, enveloped, and double stranded DNA virus, belonging to the family of Herpesviridae transmitted across mucosal membranes and nonintact skin, that migrate to nerve tissues, where they persist in a latent state [270]. HSV-1 predominates in oro-facial lesions, and it is typically found in the trigeminal ganglia, whereas HSV-2 is most commonly found in the lumbo-sacral ganglia [271].…”

Section: Herpes Simplex Virusmentioning

confidence: 99%

“…Herpes simplex virus (HSV) infections are caused by two strains, HSV-1 and HSV-2. Oro-labial infection is mainly caused by HSV-1, however, this strain is responsible for up to 53% of primary genital herpetic infection [270]. HSV-2 genital infection is much more likely to recur than genital HSV-1 infection, thus the presence of antibody to HSV-2 and a compatible clinical history would be strong presumptive evidence that the disease is recurrent genital herpes [275][276][277].…”

Section: Herpes Simplex Virusmentioning

confidence: 99%

Seroepidemiology of Toxoplasma, Rubella, Cytomegalovirus and Herpes Simplex Virus -2 in Women with Bad Obstetric History. PART II. Cytomegalovirus and Herpes Simplex Virus Infections

Alsamarai¹,

Aljumaili²

2013

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Bad obstetric history (BOH) is reported worldwide and is associated with social and psychological impacts. Cytomegalovirus and herpes simplex virus play an important role in the induction of adverse outcomes of pregnancy. Highest CMV IgG prevalence rate was reported for India (91.05%), while the lowest rate was reported for Iran (14.28%). Unfortunately, six studies in Iraq reported a high prevalence of CMV IgM in non-married, pregnant and women with BOH. The range of recent CMV infection in pregnant women with BOH was from 1.4% in Jordan to 60.2% in Iraq. In women with BOH, the highest HSV 2 prevalence (16.8%) was noted in India, while the lowest rate (1.69%) was reported in India also. In Arab countries, among women with BOH, HSV 2 IgG and IgM seroprevalence higher rates were reported for Iraq. This literature review highlights the high bacterial and viral maternal infection rate in the developing world. Urgent, concerted action is required to reduce the burden of these infections. In addition to raising awareness about the severity of the problem of maternal infections in the developing world, data from this review will be beneficial in guiding public health policy, research interests and donor funding towards achieving improvement in health care delivery.

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Type Incidence of Herpes Simplex Virus in Clinical Isolates from Patients with Herpes Genitalis

Cited by 5 publications

References 18 publications

Risk factors for bad obstetric history in Kirkuk women, Iraq

Risk factors for bad obstetric history in Kirkuk women, Iraq

Association between Herpes Simplex virus type 2 (HSV 2) and bad obstetric outcomes

Seroepidemiology of Toxoplasma, Rubella, Cytomegalovirus and Herpes Simplex Virus -2 in Women with Bad Obstetric History. PART II. Cytomegalovirus and Herpes Simplex Virus Infections

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