Type 1 diabetes mellitus, xerostomia, and salivary flow rates

Moore, Paul A.; Guggenheimer, James; Etzel, Kenneth R.; Weyant, Robert J.; Orchard, Trevor J.

doi:10.1067/moe.2001.117815

Cited by 261 publications

(195 citation statements)

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“…The results of the mean salivary flow rate obtained with the methods used in this study (weighing and aspiration) are within the flow range considered normal (0.3-0.5 mL/min) (16).…”

Section: Discussionsupporting

confidence: 63%

Use of graduated syringes for measuring salivary flow rate: a pilot study

et al. 2010

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The evaluation of the salivary flow rate is important in several situations of dental practice. However, weighing the collected salivary volume it is not a practical method in public health services. This work evaluated the use of hypodermic graduated syringes as a simpler alternative method to measure the salivary flow rate. Saliva samples were obtained from 50 individuals (31 females and 19 males) aged 8 to 32 years (mean age: 12.4 years), recruited at the outpatient dental clinics of two public health centers. After collection, the saliva was weighed in a graduated scale and the results compared with the volume obtained through its measurement, in mL, in graduated hypodermic syringes. There was a positive and significant relationship between the two methods of measuring salivary flow rates as demonstrated by the Pearson's correlation coefficient (r = 0.996, with p<0.05). Measurement of the salivary flow rate using graduated syringes demonstrated to be a reliable method, with lower cost and more practical than the traditional method of salivary weighing.

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“…The results of the mean salivary flow rate obtained with the methods used in this study (weighing and aspiration) are within the flow range considered normal (0.3-0.5 mL/min) (16).…”

Section: Discussionsupporting

confidence: 63%

Use of graduated syringes for measuring salivary flow rate: a pilot study

et al. 2010

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“…Chez l'enfant, c'est la diminution, voire la disparition de la sécrétion d'insuline qui est à l'origine du diabète [1]. Le patient diabétique présente une diminution du flux salivaire par rapport au sujet en bonne santé, ce qui favorise l'accumulation de la plaque dentaire, le développement des caries dentaires et des parodontites, tout en favorisant la prolifération de certaines bactéries salivaires, en particulier les Streptocoques mutans et des Lactobacilles [6,8,11].…”

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Relations entre le flux salivaire et le taux élevé des Streptocoques mutans et des Lactobacilles salivaires chez l’enfant diabétique de type 1

Tove

Bakayoko-Ly

N’guessan

2012

Med Buccale Chir Buccale

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Résumé -Ce travail avait pour but d'examiner les interrelations entre le faible débit salivaire et le nombre élevé des colonies de Streptocoques mutans et de Lactobacilles salivaires chez des enfants ayant un diabète sucré de type 1. L'enquête a été effectuée sur 158 enfants âgés de 5 à 12 ans (128 enfants diabétiques et 30 enfants témoins non diabétiques ne souffrant d'aucune maladie systémique) ; ils ont été sélectionnés dans une clinique pédiatrique et le centre hospitalier universitaire de Lomé (Togo), spécialisés dans le traitement des enfants diabétiques. Il s'agit d'une étude transversale comparative. Chaque groupe d'enfants a été divisé en deux tranches d'âge : de 5-8 ans et de 9-12 ans. Le débit salivaire a été évalué chez tous les patients, chaque enfant a subi un test salivaire à l'aide du « CTR bactéria de Vivadent » afin de déterminer les colonies salivaires de Streptocoques mutans et de Lactobacilles. Les 128 enfants diabétiques de type I présentent une hyposialie avec un débit salivaire de 0,59 ml.min -1 (la valeur normale est de 0,70 ml.min -1 ). La salive de ces enfants renferme une quantité importante de colonies de Streptocoques mutans et de Lactobacilles. La formation de plaque dentaire bactérienne est à l'origine de la carie et de l'inflammation des tissus parodontaux chez l'enfant diabétique de type 1. Des conseils de prophylaxie individuelle doivent être prodigués par le médecin dentiste pédiatrique.Abstract -Relations between the salivary flow rate and the important of Streptococcus mutans and Lactobacilli salivary, among the diabetic child of type 1. The aim of this study was to examine the interrelationships between the low salivary flow and the high number of salivary colonies of Streptococcus mutans and of Lactobacilli of children with diabetes mellitus type 1. The survey was conducted on 158 children between the ages of 5 to 12 years (128 children with diabetes and 30 non-diabetic children witnesses not suffering from any systemic disease); they have been selected in a pediatric clinic and the university hospital center of Lome (Togo), specialized in the treatment of children with diabetes. It is a cross-sectional comparative study. Each group of children has been divided into two age groups of 5-8 years and 9-12 years. The salivary flow was assessed on the 158 patients; each child has suffered a salivary test with the help of the "CTR bacteria of Vivadent" in order to determine the settlements of salivary mutans Streptococci and Lactobacilli. The 128 children with diabetes type 1 present a xerostomy with a salivary flow of 0.59 ml.min -1 (the normal value is 0.70 ml.min -1 ). The saliva of these children contains a significant quantity of colonies of Streptococcus mutans and Lactobacilli. The formation of bacterial plaque is at the origin of the caries and inflammation of the periodontal tissues, among the diabetic child of type I. Prophylactic advice of individual must be provided by pediatrician dentist.

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“…In their study, conducted in 45 patients with type II diabetes and 77 healthy subjects, the authors observed a significantly greater presence of glossodynia in diabetics (17.8%) compared to healthy subjects (5.6%). There is substantial evidence that smoking habit in diabetic patients significantly increases the risk of xerostomia 4 and some mucosal disorders 24 . But, results of our study indicate a significant positive correlation only between smoking and glossodynia as well as between smoking and glossopyrosis.…”

Section: Discussionmentioning

confidence: 99%

“…Chronic hyperglycemia leads to many complications, including those in oral cavity, therefore metabolic control is very important. Possible mechanisms that may be associated with some oral manifestations of diabetes are impaired chemotaxis as well as adherence and phagocytosis of neutrophil 2 , increased collagenase activity together with a decrease in collagen synthesis 3 , diabetic microangiopathy and neuropathy 4 .…”

Section: Introductionmentioning

confidence: 99%