Tympanosclerosis

Zöllner, Fritz

doi:10.1017/s0022215100052695

Cited by 44 publications

(12 citation statements)

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“… 4 Histologically there is an increase in collagen fibers as well as hyaline degeneration within the lamina propria. 5–8 The precise etiology of this condition is unclear, but associated factors include inflammatory disease of the middle ear, 9 ventilation tubes, 10 and raised partial pressure of oxygen within the middle ear after ventilation tube insertion. 11 Maw 3 reported a relationship between tympanosclerosis after ventilation tube insertion and intraepithelial hemorrhage at the time of myringotomy, and the presence of the tube in the pars tensa for greater than 6 months.…”

Section: Introductionmentioning

confidence: 99%

Tympanosclerosis in the Rat Tympanic Membrane: An Experimental Study

Russell

Giles

2002

The Laryngoscope

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Tympanosclerosis is a progressive disorder, which appears to be the main response of the rat pars tensa to prolonged sterile otitis media with effusion. The extent of involvement of the different sublayers of the pars tensa was closely related to the duration of otitis media with effusion. We propose that this new rat model for prolonged otitis media with sterile effusion is therefore a suitable animal model for the study of tympanosclerosis in the pars tensa.

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Section: Introductionmentioning

confidence: 99%

Tympanosclerosis in the Rat Tympanic Membrane: An Experimental Study

Russell

Giles

2002

The Laryngoscope

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“…Tympanosclerosis a term introduced into the English literature by Zollner (1956) is a common sequela of middle ear infection. The aim of this study was to review the literature regarding this sequela and to study the general incidence of tympanosclerosis among 775 patients with CSOM, admitted for surgery during the period 1992 to 1995 in three main hospitals.…”

Section: Introductionmentioning

confidence: 99%

Tympanosclerosis: review of literature and incidence among patients with middle-ear infection

et al. 1999

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The aim of the study was to review the literature of tympanoscierosis especially its pathogenesis, to study the general incidence of tympanoscierosis among patients with chronic suppurative otitis media (CSOM), its association with cholesteatoma and also the type of hearing loss as well as its relation to the degree and site of tympanosclerosis.Seven hundred and seventy-five patients with CSOM were studied retrospectively. A full history was taken and thorough ENT examinations were carried out. Pure tone audiograms (PTA) of all patients were done and analysed. The operative finding of tympanosclerosis as well as middle-ear status were inspected.The incidence of tympanosclerosis was found to be 11.6 per cent (90 patients out of 775 CSOM cases). Most tympanosclerosis cases had dry ear, (85.6 per cent). Of the 57.8 per cent who had myringosclerosis, their PTA showed an AB gap 20–40 dB. When sclerosis affect both the tympanic membrane and middle ear, 61 per cent of patients had an AB gap >40 dB. The association of cholesteatoma and tympanosclerosis may be regarded as uncommon, 2.2 per cent.The exact aetiology and pathogenesis of tympanosclerosis is as yet not well known. Our study concentrated on the clinical picture of tympanosclerosis among patients with CSOM. The majority of hearing loss associated with tympanosclerosis was of the conductive type.

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“…Intensives wissenschaftliches Interesse fand dieses Krankheitsbild erst wieder durch Zöllner im Jahre 1956, bedingt durch die Entwicklung der Mikrochirurgie [2]. Das während einer Otitis media gebildete Sekret enthält Immunglobuline, die für die Entstehung der Tympanosklerose von Bedeutung sein sollen.…”

Section: Abstract: Tympanosclerosis -Stapes -Stapes Mobilisation -Azunclassified