Two Unusual Presentations of Müllerian Adenosarcoma: Case Reports, Literature Review, and Treatment Considerations

MR Imaging of Uterine Adenosarcoma: Case Report and Literature Review

“…1 It is often di‹cult to make a pathological diagnosis of low grade adenosarcoma from a small histological specimen because the sarcomatous stroma may be very low grade, leading to misdiagnosis as a benign tumor such as adenoˆbro-ma or polyp. 6,7 Thus, adenosarcoma is occasionally treated as benign polypoid disease with multiple episodes of recurrence. 1,7,8 On histological examination, the components of this tumor may include uterine elements (homologous) or elements not normally found in the uterus (heterologous).…”

“…5,10 Correct histopathological diagnosis of adenosarcoma from a small specimen is often di‹cult because the sarcomatous stroma may be of very low grade, leading to misdiagnosis as benign disease like adenoˆbroma or polyp. 6,7 As a result, adenosarcoma has occasionally been treated as benign polypoid disease with repeated recurrence. 1,7,8 Therefore, gynecologists are advised to perform more aggressive sampling and evaluate the entire endometrial cavity in patients whose MR imaginĝ ndings match the pattern reported here.…”

Fallopian tube tumors: an overview

“…The prognosis of these mostly postmenopausal patients is poor (Hanjani et al, 1980). In the literature, only one adenosarcoma has been described in the fallopian tube (Gollard et al, 1995). Soft tissue tumors Leiomyosarcomas are very rare as only 37 cases have been reported in 100 years (Jacoby et al, 1993).…”

Uterine Adenosarcoma

“…4 Adenosarcoma occurring outside the female genital tract likely represents tumors arising from preexisting endometriosis. [5][6][7] Some studies suggest that the use of tamoxifen may have a role in the pathogenesis of adenosarcoma. [8][9][10][11] The prognosis of adenosarcoma greatly depends on stage and the presence of sarcomatous overgrowth.…”