Two Synchronous Colonic Adenocarcinomas, a Gastric Schwannoma and a Mucinous Neoplasm of the Appendix: a Case Report

Sousa, Diogo; Allen, M. Shannon; Pinto, Alda; Ferreira, Andreia; Cruz, Ana; Marinho, Diogo; Cusati, Pierpaolo; Martins, José Augusto

doi:10.1007/s12029-015-9708-1

Cited by 3 publications

(1 citation statement)

References 7 publications

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“…While schwannomas typically occur as a solitary mass, demonstration of multiple or synchronous lesions in the same patient is commonly associated with neurofibromatosis type 2, schwannomatosis, and Carney's complex [ 3 ]. Although there have been case reports of a synchronous schwannoma and adenocarcinoma, their tumor location is common to a contiguous organ (gastrointestinal tract) [ 15 , 16 ]. Such synchronous tumors with remote locations were only seen in 2 cases involving a colon and rectal adenocarcinoma with concurrent pelvic schwannoma [ 17 , 18 ].…”

Section: Discussionmentioning

confidence: 99%

Large benign schwannoma of the greater omentum with synchronous cervical cancer: A case report

Yap

Santos

Roble

2021

International Journal of Surgery Case Reports

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Introduction and importance Schwannomas are uncommon tumors of the omentum with only 16 reported cases originating from the greater omentum in the literature. We report for the first time a synchronous presentation of an omental schwannoma and cervical cancer. Case presentation A 37-year-old female presented with an abdominal mass and heavy vaginal bleeding. An 11.5 × 14.6 × 16.6 cm complex omental mass and 5.4 × 6.2 × 4.4 cm lobulated heterogeneous cervical mass were noted on CT-scan. Wide excision of the complex mass and radical hysterectomy with bilateral salpingo-oophorectomy and pelvic lymph node dissection was performed. The final biopsy revealed benign omental schwannoma and poorly differentiated cervical adenocarcinoma. Clinical discussion Schwannomas originating from the greater omentum are less common than in the lesser omentum due to the paucity of nervous tissue in the former. They can undergo malignant transformation and the most common presentation is abdominal pain/discomfort. Larger tumors may cause catastrophic bleeding. Prompt surgery should be offered and wide local excision with sufficient margins be performed when there is suspicion of malignancy. Schwannomas presenting with multiple or synchronous lesions are commonly associated with neurofibromatosis type 2, schwannomatosis, and Carney's complex. Whether this co-occurrence is simply incidental or has a causal relationship remains to be established. Conclusion Benign schwannoma of the greater omentum is rare and only requires complete tumor excision. However, surgeons should be aware that synchronous presentation of cervical cancer is possible and that thorough examination of both sites should be undertaken when either primary tumor presents.

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Section: Discussionmentioning

confidence: 99%

Large benign schwannoma of the greater omentum with synchronous cervical cancer: A case report

Yap

Santos

Roble

2021

International Journal of Surgery Case Reports

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What About Gastric Schwannoma? A Review Article

Lauricella

Valeri

Mascianà

et al. 2020

J Gastrointest Canc

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Gastric Schwannoma: A Tumor Must Be Included in Differential Diagnoses of Gastric Submucosal Tumors

Feng-jie

Zhu

et al. 2017

Case Reports in Gastrointestinal Medicine

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Gastric schwannoma (GS) is a rare neoplasm of the stomach. It accounts for 0.2% of all gastric tumors and is mostly benign, slow-growing, and asymptomatic. Due to its rarity, GS is not widely recognized by clinicians, and the precise differential diagnosis between GS and other gastric submucosal tumors remains difficult preoperatively. The present study reports a case of GS misdiagnosed as gastrointestinal stromal tumor and reviews the clinical, imaging, and pathological features, treatment, and follow-up of 221 patients with GS previously reported in the English literature. Although GS is rare, the case reported in the current study highlights the importance of including GS in differential diagnoses of gastric submucosal tumors. Furthermore, the findings of the review suggest that although many cases are asymptomatic, the most common symptoms are abdominal pain or discomfort, not gastrointestinal bleeding, and malignant GSs present with clinical symptoms more commonly. Although large-sample multicenter studies on the efficacy, safety, and oncological outcomes of minimally invasive techniques are required, the findings presented herein may be helpful for clinicians when diagnosing or treating GS.

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Two Synchronous Colonic Adenocarcinomas, a Gastric Schwannoma and a Mucinous Neoplasm of the Appendix: a Case Report

Cited by 3 publications

References 7 publications

Large benign schwannoma of the greater omentum with synchronous cervical cancer: A case report

Large benign schwannoma of the greater omentum with synchronous cervical cancer: A case report

What About Gastric Schwannoma? A Review Article

Gastric Schwannoma: A Tumor Must Be Included in Differential Diagnoses of Gastric Submucosal Tumors

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