Two new triterpenoid saponins from the aerial parts ofAnemone taipaiensis

Abstract

Phytochemical study on the aerial parts of Anemone taipaiensis for the first time led to the isolation of two new oleanane-type triterpenoid saponins 1 and 2, together with four known saponins (3-6). Their structures were elucidated by extensive spectroscopic analysis and chemical evidences. Saponins 2-4 exhibited cytotoxicity against human glioblastoma U251MG cell line with IC50 values ranging from 1.56 to 80.62 μM.

Triterpenoid Saponins from Anemone rivularis var. Flore-Minore and Their Anti-Proliferative Activity on HSC-T6 Cells

“…[9]. As part of our continuing study to explore bioactive natural products from the genus Anemone [10,11,12,13,14,15,16,17], we continued the investigation of this plant. In our present study, five new triterpenoid saponins ( 1 – 5 ), together with eight known ones ( 6 – 1 3 ) (Figure 1) were isolated, among which lupane-type saponins ( 3 and 12 ) were first reported from the Anemone genus.…”