Two new tetrahydroisoquinoline analogs from Indian medicinal plant Annona squamosa

Jayendra,; Kumar, Yogesh; Kumar, Shiv

doi:10.1016/j.jopr.2013.06.022

Cited by 7 publications

(2 citation statements)

References 9 publications

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“…Table 2 shows some of the previously isolated alkaloids from A. squamosa. 2 N-Nitrosoxylopine Bark (41) 3 Roemerolidine Bark (41) 4 Duguevalline Bark (41) 5 Lanuginosine Twigs (39) ISSN: 3009-7061 Twigs (42) 7 Coclaurine Leaves (43) 8 O-Methylarmepavine Twigs (39) 9 N-Methyl-6,7-dimethoxyisoquinolone Twigs (39) 10 N-Methylcorydaldine Twigs (39) 4.3. Diterpenoids A. Squamosa diterpenoids are concentrated in plant stems and bark with ent-kaurane diterpenoids being the most prevalent type (14) .…”

Section: Alkaloidsmentioning

confidence: 99%

Annona squamosa L.: A promising herbal remedy - Insights into its biological activities and phytochemical composition

Shokr,

Elsohafy,

Darwish

et al. 2024

Journal of Advanced Pharmaceutical Sciences

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Annonaceae is a large, prominent family within the Magnoliales order, containing many genera. Among these, the genus Annona holds significance for its substantial diversity and traditional medicinal value. Annona squamosa L. is one of the most common species of this genus. This tropical species, commonly known as the sugar apple, exhibits distinct morphological features. Phytochemical investigations of A. squamosa revealed the presence of acetogenins, alkaloids, diterpenes, and cyclopeptides in various plant parts. Acetogenins, found mainly in seeds and representing the major active constituents, possess distinctive structures and biological activities. Alkaloids, predominantly isolated from leaves, represent the second major class of A. squamosa active constituents. A. squamosa exhibits a wide array of pharmacological activities encompassing anti-tumor, anti-inflammatory, antioxidant, antidiabetic, antimicrobial, antiviral, immunomodulatory, and wound-healing properties. This comprehensive review highlights the botanical characteristics, phytochemical composition, and diverse pharmacological activities of A. squamosa and aims to be a guide for further research on A. squamosa.

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Section: Alkaloidsmentioning

confidence: 99%

Annona squamosa L.: A promising herbal remedy - Insights into its biological activities and phytochemical composition

Shokr,

Elsohafy,

Darwish

et al. 2024

Journal of Advanced Pharmaceutical Sciences

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“…Current review contains wide information on anti-diabetic medicinal plants cultivated throughout world. [1][2][3] Types of diabetes mellitus They are categorised into two types-Type I and Type II diabetes mellitus.…”

Section: Introductionmentioning

confidence: 99%

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2018

IJCTR

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The mankind has received a gift from mother-nature in the form of natural laboratories present within diversified plant kingdom. The plants create secondary metabolites for their own safety and many of these secondary metabolites are useful for human beings in various kinds of ailments. Diabetes is not an exception to this, there are many secondary metabolites isolated from plants which are now being utilized for treatment. The significance of isolating metabolites from plants is that they have comparatively very less side effects as compared to allopathic system of medicine (oral hypoglycaemic agents). This review takes into account, the recent updates in the treatment of diabetes mellitus using herbal products and phytochemical constituents reported so far.A total number of 150 plant species belonging to numerous families are presented in this review which is useful in the treatment of diabetes mellitus. Article also contains more than fifty medicinal compounds recently updated in literature. The most important families in present review are fabaceae and cucurbitaceae. The plants from these families are found to be of high therapeutic value to treat diabetes mellitus however families like musaceae, punicaceae and aloaceae have been found to contain least number of effective plant species. The plant parts contributing mostly active compounds are leaves, fruit & seeds.

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Medicinal plants of Ecuador: a review of plants with anticancer potential and their chemical composition

et al. 2015

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Two new tetrahydroisoquinoline analogs from Indian medicinal plant Annona squamosa

Cited by 7 publications

References 9 publications

Annona squamosa L.: A promising herbal remedy - Insights into its biological activities and phytochemical composition

Annona squamosa L.: A promising herbal remedy - Insights into its biological activities and phytochemical composition

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Medicinal plants of Ecuador: a review of plants with anticancer potential and their chemical composition

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