Two New Diterpenoids from<i>Mallotus apelta</i>Muell.Arg.

Cheng, Xiaofang; Chen, Zhongliang; Meng, Zeng-Mu

doi:10.1080/10286029908039860

Cited by 20 publications

(3 citation statements)

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“…Dolabrane diterpenoids are a small group of natural products reported mainly from plants. To date, only 37 dolabranes have been characterized from the plant genera Araucaria , Croton , Dichapetalum , Endospermum , Erythroxylum , Fagonia , Givotia , Helichrysum , Mallotus , Petalostigma , Rondeletia, Trigonia , and Thujopsis ,− ,− and from the liverwort Schistochila aligera , whereas 18 dolabranes have been identified from the mangrove, Ceriops tagal . Obviously, C. tagal is a valuable source for the production of dolabranes.…”

Section: Resultsmentioning

confidence: 99%

Dolabranes from the Chinese Mangrove, Ceriops tagal

et al. 2010

J. Nat. Prod.

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Six new dolabranes, named tagalsins P-U (1-6), were isolated from stems and twigs of a Chinese mangrove, Ceriops tagal, along with seven known dolabranes, an abietane, and a pimarane. The structures of these compounds were established on the basis of spectroscopic data or comparison with data in the literature. The relative configurations of tagalsins P and Q (1, 2), two new 15,16-dinor-dolabranes, were confirmed by means of single-crystal X-ray diffraction analysis. This is the first report of 16-nordolabranes and 15,16-dinordolabranes from plants of the Ceriops genus. Tagalsins Q (2), R (3), and U (6) showed moderate antifeedant activity against the third-instar larvae of Brontispa longissima at a concentration of 1 mg/mL. However, none of the new dolabranes exhibited significant activity against human cancer cell lines.

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Section: Resultsmentioning

confidence: 99%

Dolabranes from the Chinese Mangrove, Ceriops tagal

et al. 2010

J. Nat. Prod.

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“…2005), tannins (Amakura and Yoshida 1996; Wei et al. 2004), terpenoids (Cheng and Chen 1999; Cheng et al. 1999; Huang et al.…”

Section: Introductionmentioning

confidence: 99%

ANTIOXIDANT ACTIVITY OF EXTRACTS OF MALLOTUS PHILIPPINENSIS FRUIT AND BARK

Arfan

Amin

Karamać

et al. 2007

Journal of Food Lipids

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Several extracts from Mallotus philippinensis fruits and bark were prepared and evaluated for their total antioxidant activity (TAA), antiradical activity against DPPH· (2,2‐diphenyl‐1‐picrylhydrazyl radical) and reducing power. The total phenolics and tannin contents in extracts were determined. The extract of the bark showed the strongest antiradical activity and reduction power; its TAA was 5.27 mmol Trolox equivalents/g. The TAA of other extracts ranged from 0.05 to 1.79 mmol Trolox equivalents/g extract. The content of total phenolics in the bark extract was 541 mg/g. The content of tannins in MP‐4, expressed as absorbance units per mg at 500 nm, was found to be 0.412. Several phenolic constituents in the extracts were detected by reverse‐phase high‐performance liquid chromatography using a gradient solvent system with UV‐DAD detection. Acetone was a suitable solvent for extraction of natural antioxidants from M. philippinensis fruits. PRACTICAL APPLICATIONS An acetonic and methanolic extraction of Mallotus philippinensis fruit and bark affords extracts that have been characterized as possessing strong antioxidant activities; this may open new avenues for the utilization of these extract as nutraceuticals. The biological activity of compounds present in the extracts has been well documented in many studies published in scientific journals. We want to emphasize that a procyanidin‐rich extract from pine (Pinus maritime) bark was patented under the trade name of Pycnogenol (PYC) and is utilized throughout the world as a nutritional supplement and as a phytochemical remedy for various diseases ranging from chronic inflammation to circulatory dysfunction (Packer et al. 1999).

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“…Flavonoids (52-85) have been reported from M. apelta (leaves and branches), M. barbatus (leaves), M. conspurcatus (roots), M. metcalfianus (leaves and stems), and M. japonicus (leaves) (Table 3). Chalcones (86)(87)(88)(89)(90)(91)(92)(93)(94)(95)(96)(97)(98)(99)(100)(101)(102)(103)(104) have been reported from M. philippinensis (fruits) and M. philippensis (fruits) (Table 4).…”

Section: Flavonoids and Chalconesmentioning

confidence: 99%

Genus mallotus (euphorbiaceae): a review on traditional medicinal use, phytochemistry and biological activities

Anh

Park

Trang³

et al. 2022

Vietnam J. Sci. Technol.

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Ethnopharmacological relevance: The genus Mallotus (Euphorbiaceae family) includes 124 accepted names and distributes in tropical and sub-tropical regions. Some Mallotus species are used in traditional medicines for the treatment of chronic hepatitis, enteritis stomach, disorders, cholelithiasis, anti-cancer, gastric, and duodenal ulcers. Aim of the study: According to the Scifinder database, this is the first review study that focuses on the phytochemistry and pharmacology of Mallotus genus (17 Mallotus species) to understand the link between the traditional medicinal uses, phytochemistry, and bioactivities. Thus, they provides a scientific fundamental for further research in the phytochemical and pharmacological activities of their species. Materials and methods: Information about the Mallotus genus was collected using various databases, such as Web of Science, SciFinder, PubMed, Sci-hub, Google Scholar, Wiley, Elsevier, ACS publications, and SpringerLink between 1978 and 2021. Plant names were validated by “The Plant List” (www.theplantlist.org). Results: Up to now, total 325 compounds were reported from Mallotus species, including phloroglucinols, steroids, coumarins, benzopyrans, flavonoids, chalcones, galics, and bergenins. The extracts and phytochemical constituents of the Mallotus genus are a rich source of biologically active, including anti-cancer, anti-inflammatory, immunoregulatory, antioxidant, antibacterial, antifungal, anti-virus, and other activities. Conclusions: The review indicated that the Mallotus genus is a promising source of biological activities compounds, special anti-cancer chromanes. The results of this review confirm the great potential of Mallotus species. Thus, it will be helpful for further research in the phytochemistry and pharmacology of the Mallotus genus.

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Two New Diterpenoids fromMallotus apeltaMuell.Arg.

Cited by 20 publications

References 2 publications

Dolabranes from the Chinese Mangrove, Ceriops tagal

Dolabranes from the Chinese Mangrove, Ceriops tagal

ANTIOXIDANT ACTIVITY OF EXTRACTS OF MALLOTUS PHILIPPINENSIS FRUIT AND BARK

Genus mallotus (euphorbiaceae): a review on traditional medicinal use, phytochemistry and biological activities

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