Two new 24-hydroxylated asterosaponins from Culcita novaeguineae

Marine natural products

“…More regular 6-hydroxy-steroidal glycosides kurilensosides I 1009 and J 1010 were subsequently reported from the same collection of H. kurilensis. 820 A monosulfated analogue 1018 (Actinopyga lecanora, Hainan Is., South China Sea) of the well-known sea cucumber metabolite holothurin B 821 was unfortunately assigned a trivial name (lecanoroside A). 818 The same tubulin bioassay was used to direct the isolation of novaegui- (Sanya Bay, South China Sea).…”

Asterosaponins: Structures, Taxonomic Distribution, Biogenesis and Biological Activities

“…One of these groups ("shortened" asterosaponins) contains only one sugar in carbohydrate moiety when compared with classical asterosaponins, but this sugar bears an additional sulfate group that partly compensates the loss in hydrophilicity. Novaeguinosides A and B and asterosaponin without a name (144-146) have 4-O-sulfate of quinovopyranose unit and aglycons with side chain also bearing polar substituents, as in trisaccharide asterosaponins 44-46 from the same starfish Culcita novaeguinea [37,38]. Novaeguinosides A (144) is the first asterosaponin with three sulfate groups (Figure 6).…”

“…Regularioside A New Caledonia, shallow waters [32] «----» [30] Ophidiaster ophidianus ----------» [29] Hippasterioside C «-----------» [29] Hippasterioside D «-----------» [29] Family Ophidiasteridae Linckia laevigata Laevigatoside «-----------» [30] Ophidiaster ophidianus Ophidianoside B Bay of Naples, Italy, shallow waters 33 ----------» [29] Hippasterioside C «-----------» [29] Hippasterioside D «-----------» [29] Family Ophidiasteridae Linckia laevigata Laevigatoside «-----------» [30] Ophidiaster ophidianus Ophidianoside B Bay of Naples, Italy, shallow waters 33 ----------» [29] Hippasterioside C «-----------» [29] Hippasterioside D «-----------» [29] Family Ophidiasteridae Linckia laevigata Laevigatoside «-----------» [30] Ophidiaster ophidianus Ophidianoside B Bay of Naples, Italy, shallow waters 33 ----------» [29] Hippasterioside C «-----------» [29] Hippasterioside D «-----------» [29] Family Ophidiasteridae Linckia laevigata Laevigatoside «-----------» [30] Ophidiaster ophidianus Ophidianoside B Bay of Naples, Italy, shallow waters 33 ---------- ---------- ----------» [37] Without name «-----------» [38] Oreaster reticulatus Reticulatoside A Grand Bahama Isl., Bahamos, depth was not reported [39] 38…”

“…Without name «-----------» [38] Oreaster reticulatus 47 Reticulatoside A Grand Bahama Isl., Bahamos, depth was not reported [39] Sanya Bay, China, depth was not reported [36] 44 ---------- ----------» [37] Without name «-----------» [38] Oreaster reticulatus Reticulatoside A Grand Bahama Isl., Bahamos, depth was not reported [39] 39 Without name (Asterosaponin 1) «----------- ----------» [37] Without name «-----------» [38] Oreaster reticulatus Reticulatoside A Grand Bahama Isl., Bahamos, depth was not reported [39] 39 Without name (Asterosaponin 1) «-----------…”

“…Reticulatoside A Grand Bahama Isl., Bahamos, depth was not reported [39] «----» [38] Oreaster reticulatus…”