Two Modes of Acupuncture as a Treatment for Hot Flushes in Men with Prostate Cancer—A Prospective Multicenter Study with Long-Term Follow-Up

Frisk, Jessica; Spetz, Anna-Clara; Hjertberg, Hans; Petersson, Bill; Hammar, Mats

doi:10.1016/j.eururo.2008.02.002

Cited by 59 publications

(54 citation statements)

References 27 publications

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“…[53][54][55][56][57][58][59][60][61][62][63][64][65][66][67][68][69] Next, trials that used EA adjunctively to MA (designated as MA versus MA + EA) were differentiated from trials that directly compared the two procedures (MA versus EA). If all procedures in the EA group before electrostimulation were the same as procedures in the MA group (e.g., de qi was initially elicited in each group), the trial was considered MA versus MA + EA; if the pre-electrostimulation procedure in the EA group was different (e.g., if de qi was elicited only in the MA group), the trial was considered MA versus EA.…”

Section: Clinical Trials Comparing Ma and Eamentioning

confidence: 99%

Manual and Electrical Needle Stimulation in Acupuncture Research: Pitfalls and Challenges of Heterogeneity

Langevin

Schnyer

MacPherson

et al. 2015

The Journal of Alternative and Complementary Medicine

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In the field of acupuncture research there is an implicit yet unexplored assumption that the evidence on manual and electrical stimulation techniques, derived from basic science studies, clinical trials, systematic reviews, and meta-analyses, is generally interchangeable. Such interchangeability would justify a bidirectional approach to acupuncture research, where basic science studies and clinical trials each inform the other. This article examines the validity of this fundamental assumption by critically reviewing the literature and comparing manual to electrical acupuncture in basic science studies, clinical trials, and meta-analyses. The evidence from this study does not support the assumption that these techniques are interchangeable. This article also identifies endemic methodologic limitations that have impaired progress in the field. For example, basic science studies have not matched the frequency and duration of manual needle stimulation to the frequency and duration of electrical stimulation. Further, most clinical trials purporting to compare the two types of stimulation have instead tested electroacupuncture as an adjunct to manual acupuncture. The current findings reveal fundamental gaps in the understanding of the mechanisms and relative effectiveness of manual versus electrical acupuncture. Finally, future research directions are suggested to better differentiate electrical from manual simulation, and implications for clinical practice are discussed.

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Section: Clinical Trials Comparing Ma and Eamentioning

confidence: 99%

Manual and Electrical Needle Stimulation in Acupuncture Research: Pitfalls and Challenges of Heterogeneity

Langevin

Schnyer

MacPherson

et al. 2015

The Journal of Alternative and Complementary Medicine

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“…Estrogen-therapy alleviates hot flashes in women, and testosterone given to men treated by castration due to prostate cancer, (although contraindicated), alleviates flashes. In men with androgen ablation therapy alternative treatments include therapies such as acupuncture, diethylstilbestrol, gabapentin, venlafaxine, medroxyprogesterone acetate and cyproteroneacetate [27][28][29][30]. To our knowledge, no controlled treatment trials have been performed in healthy aging men with flushes.…”

Section: Discussionmentioning

confidence: 99%

Hot flushes in healthy aging men differ from those in men with prostate cancer and in menopausal women

Holm

Thorell

Theodorsson

et al. 2011

Gynecological Endocrinology

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Abstract:Calcitonin Gene-Related Peptide (CGRP) seems to be involved in hot flushes in women and in castrated men. Therefore, we studied whether the plasma concentrations of CGRP changed during flushes in a group of healthy aging men. Twelve men (49-71 years) with no history of current or former prostate cancer or hormonal treatment reporting ≥20 flushes/week were investigated. Blood samples were drawn during and between flushes for analysis of CGRP and also androgen concentrations, i.e. Testosterone and Bioavailable Testosterone were analysed.Skin temperature and skin conductance were monitored.

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“…The key data are summarised in Table 1 [3,5,[13][14][15][16]. The included six studies comprised one RCT [13] and five UOSs [3,5,[14][15][16]. Two trials originated from Sweden [13,14], three trials were conducted in the USA [3,5,16], and one trial was from the UK [15].…”

Section: Study Descriptionmentioning

confidence: 99%

“…The key data are summarised in Table 1 [3,5,[13][14][15][16]. The included six studies comprised one RCT [13] and five UOSs [3,5,[14][15][16].…”

Section: Study Descriptionmentioning

confidence: 99%

Acupuncture for treating hot flushes in men with prostate cancer: a systematic review

Lee

Kim

Shin

et al. 2009

Support Care Cancer

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Two Modes of Acupuncture as a Treatment for Hot Flushes in Men with Prostate Cancer—A Prospective Multicenter Study with Long-Term Follow-Up

Cited by 59 publications

References 27 publications

Manual and Electrical Needle Stimulation in Acupuncture Research: Pitfalls and Challenges of Heterogeneity

Manual and Electrical Needle Stimulation in Acupuncture Research: Pitfalls and Challenges of Heterogeneity

Hot flushes in healthy aging men differ from those in men with prostate cancer and in menopausal women

Acupuncture for treating hot flushes in men with prostate cancer: a systematic review

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