Two Lethal Endosulfan Poisonings in Man

Demeter, J.; Heyndrickx, A

doi:10.1093/jat/2.2.68

Cited by 17 publications

(3 citation statements)

References 13 publications

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“…Autopsies revealed edema and congestion of the brain and lungs, hemorrhage of the medullary layer of the kidneys, acute lung emphysema, and chromatolysis of the neurons (Terziev et al, 1974). Dark-red/purple body and cyanotic face is also reported Autopsy revealed edematous lungs (Demeter and Heyndrickx, 1978). Acute renal failure, disseminated intravascular coagulation, thrombi in the pulmonary arteries and aorta, and cardiogenic shock may be seen.…”

Section: Human Toxicitymentioning

confidence: 88%

Pathology of Endosulfan

Özmen¹

2011

Pesticides in the Modern World - Effects of Pesticides Exposure

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Section: Human Toxicitymentioning

confidence: 88%

Pathology of Endosulfan

Özmen¹

2011

Pesticides in the Modern World - Effects of Pesticides Exposure

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“…Endosulfan (6,7,8,9,10,10-hexachloro-1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepin 3-oxide, CAS Registry Number 6994-04-3) is a polychlorinated compound ( Figure 1). It is a cream to brown colored solid that may appear crystalline or in flakes.…”

Section: Chemistrymentioning

confidence: 99%

“…4 Endosulfan is associated with a high fatality rate in humans when ingested accidentally, from food or water contaminated, or in suicide cases. [5][6][7][8][9][10][11][12][13] It is also a substance that imitates or enhances the effect of the female hormone estrogen, which means it can cause reproductive and developmental damage in both animals and humans. Researchers studying children from an isolated village in Kerala, India, have linked endosulfan exposure to delays in sexual maturity among boys.…”

Section: Introductionmentioning

confidence: 99%

Clinical Aspects of the Poisoning by the Pesticide Endosulfan

Patočka¹,

Wu²,

França³

et al. 2016

Química Nova

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publicado na web em 06/06/2016 Endosulfan is an organochlorine insecticide, widely used in insect control. Unfortunately, it is also an acute neurotoxic compound to both insects and mammals, including humans, and has been responsible for many severe poisonings and several fatal cases. Endosulfan also imitates or enhances the effect of the female hormone estrogen, having the capability of causing reproductive and developmental damage in both, animals and humans, and its exposure has been linked to liver tissue injury. This persistent lipophilic compound is one of the most abundant organochlorine pesticides in the environment, capable of undergoing long range transport to remote locations such as the Arctic. It is practically water-insoluble, but readily adheres to clay particles and persists in soil and water for several years. Its indiscriminate and injudicious use in the control of insects on a wide range of agricultural products and in the extermination of household pests, has considerably increased the hazard risk for human health. Also, this compound has a high fatality rate in humans when ingested accidentally, from food or water contaminated, or in suicidal cases. The aim of this article is to review and summarize chemical, biochemical, environmental, and toxicological data of endosulfan and draw attention to its toxicological potential risk to human health.

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Endosulfan

Schmidt

2004

Bodengefährdende Stoffe: Bewertung ‐ Stoffdaten ‐ Ökotoxikologie ‐ Sanierung

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Beim dem technischen Produkt Endosulfan (CAS‐Nr.: 115‐29‐7, auch 6,7,8,9,10,10‐Hexachlor‐1,5,5a,6,9,9a‐hexahydro‐6,9‐methano‐2,4,3‐benzodioxathiepin‐3‐oxid) handelt es sich um ein Gemisch aus zwei Isomeren (α‐Endosulfan und β‐Endosulfan). Endosulfan ist ein nicht‐systemisches Insektizid und Akarizid mit breiten Aktivitätsspektrum, das in den 50er Jahren des 20. Jahrhunderts auf den Markt gebracht wurde. Es ist mittlerweile in vielen Staaten verboten und wurde 2011 in die POP‐Liste der Stockholmer Konvention aufgenommen. Trotz seines (langsamen) Abbaus in Böden besteht durch die relativ hohe Giftigkeit ein Gefahrenpotenzial.

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Two Lethal Endosulfan Poisonings in Man

Cited by 17 publications

References 13 publications

Pathology of Endosulfan

Pathology of Endosulfan

Clinical Aspects of the Poisoning by the Pesticide Endosulfan

Endosulfan

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