Two isomeric and distinguishable H₂S fluorescence probes for monitoring spoilage of eggs and visualizing exogenous and endogenous H₂S in living cells

Abstract

Accurate fabrication of fluorescence probes to efficiently monitor and detect H2S levels in the fields of foodstuffs and physiology is crucial.

Hydrogen Sulfide: An Emerging Precision Strategy for Gas Therapy

“…ity and response time of detection, fluorescent probes with superior advantages for monitoring H 2 S in real time have been widely investigated. [337][338][339][340][341][342][343][344][345][346][347][348][349][350] However, the applications for in vivo H 2 S detection are severely limited because of the low tissue penetration and spatial resolution, as well as the poor photostability. Thus, other advanced imaging techniques for superior H 2 S detection have been developed, such as NIR-I/II, PA, MR, and PET imaging, allowing for early detection and diagnosis of diseases, realtime observation of biological processes during targeted delivery, cellular uptake, and biodistribution of therapeutics in a detailed manner (Table 3).…”

A novel “off–on” peptide fluorescent probe for the detection of copper and sulphur ions in living cells

“…Many fluorescent probes have been reported for the detection of Cu 2+ and S 2− , especially organic small molecule probes, such as: hydrazide, doped carbon dots, 2′,7′-dichlorofluorescein, imidazole dyes, Schiff base, naphthylamine, salamo, phenanthrene, and phenyl 2-(benzoylthio)benzoate. In contrast, 4,9,18–30 peptidic probes are better suited for bioassays and cellular imaging than most small-molecule probes because they are water soluble, biocompatible, low toxicity, and do not require organic solvents as co-solvents. See Tables S1 and S2 (ESI†) for more information.…”

Multicomponent Reaction Based Tolyl-substituted and Pyrene-Pyridine Conjugated Isomeric Ratiometric Fluorescent Probes: A Comparative Investigation of Photophysical and Hg(II)-Sensing Behaviors

“…One of the stimulated examples of such category of isomeric probes are Z/E-isomers of tetraphenylethene (TPE) derivative, these derivatives were synthesized and explored their promising photophysical characters [10]. In 2020, the phenanthro [9,10-d]imidazole benzene sulfonamide-based two isomeric uorescent probes were developed for visualizing H 2 S in living cells by altering the position of substituted sulfonamide group on phenyl ring [11]. Very recently, an another interesting example is reported related to the aggregations of pyrene based isomers, in this studies the synthesized pyrene monosubstituted phthalonitrile positional isomers displays the distinct aggregation induced emission behaviors [12].…”