Two infants with COVID-19 acquired from infected mothers: The incompatibility of maternal intensity and infant lung involvement: A case report

Abstract

IntroductionThe outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was declared a public health emergency by world health organization (WHO) on 30 January 2020. Recent studies have suggested that infants present the symptoms of COVID-19. Although the presentation of the disease in babies is variable, there are limited studies about the infected babies with 2019-nCoV.Case presentationIn this study, we have presented a case report of two infants with COVID-19. According to the simultaneity of maternal infection, maternal-fetal transmission or postnatal transmission was suggested. The chest radiography of one of the neonates suggested severe lung involvement. Despite the supportive and resuscitation attempts, poor clinical condition of him led to his death. Fortunately, the two mothers and one of the babies were discharged from the hospital with a good general condition.ConclusionIn this paper, we have reported two infants who had positive results of COVID-19 testing at day one of life. The babies had worse clinical conditions than their mothers and the intensity of pneumonia and the level of lung involvement of the infants were not associated with the stage and disease severity of the mothers who infected with 2019-nCoV.

Death of a neonate with suspected coronavirus disease 2019 born to a mother with coronavirus disease 2019 in Iran: a case report

“…In a study by Moeindarbary et al, researchers reported infants with coronavirus infection and that they had worse clinical condition than their mothers. The severity of pneumonia and the degree of lung involvement in these infants were not related to the stage and severity of the disease in infected mothers [21]. Chen et al's study in Wuhan also reported vertical transmission between pregnant women with COVID-19 and their infants [22].…”