Two-dimensional numerical simulation of the red blood cell floating in a plasma-alcohol solution through stenosis in a microvessel

Ni, Aleksey; Cheema, Taqi Ahmad; Kwak, Moon Kyu; Park, Cheol Woo

doi:10.1007/s13367-014-0033-1

Cited by 2 publications

(1 citation statement)

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“…The present work is the extension of our previous research on the deformability and behavior of a single RBC in the stenotic microchannel under the influence of plasma-alcohol solution (Ni et al, 2013). The previous work purposed ALE moving mesh method to solve the fluid structure interaction of RBC and alcohol.…”

Section: Introductionmentioning

confidence: 99%

Numerical investigation on the structural characteristics of multiple RBCs in a stenotic microcapillary under plasma-alcohol solution

Cheema

Park

2015

Korea-Aust. Rheol. J.

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Alcohol significantly affects blood rheology and influences the mechanical behavior of red blood cells (RBCs). Previous studies indicate that plasma-RBC and multiple RBC interaction are important indicators for atherosclerosis progression. Therefore, multiphysics interactions under highly viscous conditions of alcohol consumption and stenosis structure must be investigated. A 2D microcapillary model, wherein multiple RBCs float through a stenotic structure, was established to investigate the effect of alcohol on cell motion and deformability under various flow conditions. Results show that the deformed cells inside the stenosis increase flow resistance and increase plasma velocity gradient in the pre and post stenotic regions. Moreover, the effect of the initial RBC position is important describing the RBC deformation pattern. The structural properties of RBCs may be significantly affected when the stenosis path is filled by cells that increase flow resistance.

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Section: Introductionmentioning

confidence: 99%