Two different reorganization patterns after rehabilitative therapy: An exploratory study with fMRI and TMS

Hamzei, Farsin; Liepert, Joachim; Dettmers, Christian; Weiller, Cornelius; Rijntjes, Michel

doi:10.1016/j.neuroimage.2005.12.035

Cited by 142 publications

(147 citation statements)

References 65 publications

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“…TMS has been used as a tool for predicting recovery of function (Stinear et al, 2007, Trompetto et al, 2000, to determine the type or location of reorganisation occurring within the cortex (Caramia et al, 2000, Hamzei et al, 2006, Shimizu et al, 2002, Turton et al, 1996, or to investigate the neurophysiological effect of interventions designed to enhance recovery (Brouwer and Ambury, 1994, Liepert et al, 2000, Wittenberg et al, 2003. The response to TMS is primarily recorded using motor evoked potentials (MEPs) obtained from musculature in the periphery.…”

Section: Introductionmentioning

confidence: 99%

Reliability of lower limb motor evoked potentials in stroke and healthy populations: How many responses are needed?

Lewis

Signal

Taylor

2014

Clinical Neurophysiology

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Highlights Intrasession reliability of lower limb motor evoked potentials (MEPs) is excellent in patients with stroke when using as few as 6 responses  Intersession reliability of MEPs is poor in patients with stroke, questioning the ability of this measure to reliably capture changes in corticomotor excitability over time  Measuring the amplitude of each single MEP or using MEP area provides a more reliable measure of MEP size than averaging non-rectified responses AbstractObjective: To determine the intra-and inter-session reliability of motor evoked potential (MEP) size parameters in the lower limb of patients with stroke, focussing on the number of MEPs collected and the method of measuring MEP size. Methods: Transcranial magnetic stimulation was used to elicit MEPs in the soleus muscle of patients with stroke (n=13) and age-matched healthy participants (n=13) during low level muscle activation. Two sets of 10 responses were collected in the first session and a further 10 responses collected in a second session held 7 days later. Four MEP size measurements were made using 4, 6, 8, or all 10 of the MEPs collected. Intra-and inter-session reliability was examined using intraclass correlation coefficients (ICC) and typical percentage error. Results: Intrasession ICC statistics using 6 or more MEPs were >0.85 in the stroke group but intersession values were all <0.5.Reliability was best when measuring parameters from individual MEPs rather than averaged responses. Conclusions: Reliability of intrasession MEP size is excellent in the lower limb of patients with stroke using as few as 6 MEPs but intersession reliability is poor. Significance:Comparing MEP size measures across two or more sessions is questionable in the lower limb of patients with stroke.3

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Section: Introductionmentioning

confidence: 99%

Reliability of lower limb motor evoked potentials in stroke and healthy populations: How many responses are needed?

Lewis

Signal

Taylor

2014

Clinical Neurophysiology

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“…Later, these authors applied the stimulation in a temporal window after administering lamotrigine and valproic acids and demonstrated the reliability of TMS-fMRI coregistration in the assessment of the effect of medications both locally and in cortical networks [110]. Hamzei and coworkers assessed the effects of rehabilitative therapy after a stroke (of either the middle cerebral artery or internal capsule) that involved the motor functions of the hand area [111]. Paired pulse was applied to investigate intracortical inhibition and intracortical facilitation; BOLD response was measured following passive and active movements of either the affected or the non-affected hand.…”

Section: Tms-fmri Coregistrationmentioning

confidence: 99%

Transcranial Magnetic Stimulation and Neuroimaging Coregistration

Casula¹,

Tarantino²,

Basso³

et al. 2013

Novel Frontiers of Advanced Neuroimaging

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The development of neuroimaging techniques is one of the most impressive advancements in neuroscience. The main reason for the widespread use of these instruments lies in their capacity to provide an accurate description of neural activity during a cognitive process or during rest. This important advancement is related to the possibility to selectively detect changes of neuronal activity in space and time by means of different biological markers. Specifically, functional magnetic resonance imaging (fMRI), positron emission tomography (PET), single-photon emission computed tomography (SPECT), and nearinfrared spectroscopy (NIRS) use metabolic markers of ongoing neuronal activity to provide an accurate description of the activation of specific brain areas with high spatial resolution. Similarly, electroencephalography (EEG) is able to detect electric markers of neuronal activity, providing an accurate description of brain activation with high temporal resolution. The application of these techniques during a cognitive task allows important inferences regarding the relation between the detected neural activity, the cognitive process involved in an ongoing task, and behaviour: this is known as a “correlational approach”

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“…Esta terapêutica tem-se mostrado eficaz em estudos envolvendo populações com AVC (13)(14)(15)(16)(17)(18)(19)(20), traumatismo crânio-encefálico (21), paralisia cerebral (22) e em estudos que envolvam técnicas de imagem para comprovar a reorganização cortical (23)(24)(25)(26).…”

Section: Introductionunclassified

Terapia por contensão induzida: revisão de ensaios clínicos

2010

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ResumoIntrodução: A Terapia por Contensão Induzida (TCI) é uma terapêutica que visa à recuperação da função do membro superior (MS) parético de pacientes com sequelas de um acidente vascular cerebral por meio de treinamento intensivo, uso de uma restrição no MS não-parético durante 90% do dia e pelo pacote de transferência. Objetivo: O objetivo deste trabalho é realizar uma revisão entre os estudos que compararem a TCI com outras terapêuticas. Metodologia: Foi realizada uma pesquisa nas bases de dados MEDLINE, SciELOo e ISI Web of Science com o descritor "constraint induced movement therapy" durante o mês de junho de 2008. Resultados: Foram encontrados seis artigos onde a TCI foi comparada com os métodos Bobath e Kabat. Discussão: Dentre os artigos encontrados, percebemos que há uma variação entre as amostras de cada estudo, assim como o método de avaliação entre as terapêuticas. Conclusão: A TCI mostrou-se superior em relação às outras terapêuticas. Palavras-chave:

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Two different reorganization patterns after rehabilitative therapy: An exploratory study with fMRI and TMS

Cited by 142 publications

References 65 publications

Reliability of lower limb motor evoked potentials in stroke and healthy populations: How many responses are needed?

Reliability of lower limb motor evoked potentials in stroke and healthy populations: How many responses are needed?

Transcranial Magnetic Stimulation and Neuroimaging Coregistration

Terapia por contensão induzida: revisão de ensaios clínicos

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