Two Cases Of Vulvovaginitis Caused By Shigella Flexneri And Shigella Sonnei: A Case Report

Vaginal bleeding in prepubertal females: a case ofShigellavaginitis and review of literature

“…Shigellosis has an incidence of 164.7 million cases, with 163.2 million in developing countries and the highest incidence in children aged 1–5 years old. S. flexneri is especially common in low-class or middle-class countries, including Central America in this case 1 16. Our patient could have been treated much earlier if vaginal discharge cultures were performed earlier.…”

“…Determining optimal treatment for Shigella vulvovaginitis was a challenge because of limited clinical experience due to the rarity of the disease 16. Commonly, treatment is dependent on the resistance of the bacteria.…”

“…Commonly, treatment is dependent on the resistance of the bacteria. Two common antibiotics used include oral ampicillin and sulfamethoxazole-trimethoprim 1 6 16. It is important to test for antibiotic resistance, as it is becoming more common for bacteria to be resistant to these antibiotics, especially when patients have a history of foreign travel 5 6.…”

“…Other possible treatments include fluoroquinolones, for example, ciprofloxacin, and macrolides, for example, azithromycin. Although fluoroquinolones have been known to be contraindicated in children due to development of cartilage abnormalities, there is more evidence of the safety in these antibiotics and their efficacy for vulvovaginitis against Shigella 6 16 17. Ciprofloxacin has good penetration of gynaecological mucosa compared with other antibiotics 5.…”

Asociación entre Shigella flexneri y la presencia de microulceraciones vulvovaginales en niñas peruanas prepúberes con vulvovaginitis específica

“…Ningún estudio previo resalta la presencia de microulceraciones en la zona vaginal de las pacientes afectadas (15)(16)(17), pero sí, la característica crónica de la enfermedad y su resistencia a los antibióticos (17,18). Bayramoğlu et al (19), concluye que la vulvovaginitis es frecuente en países endémicos de Shigella y que se caracterizada por un flujo sanguinolento. El conocimiento de una lesión patognomónica encontrada en el examen clínico de las niñas portadoras de la infección vaginal por Shigella flexneri, permitirá establecer un diagnóstico precoz de una de las causas más frecuentes de sangrado vaginal.…”