2022
DOI: 10.1080/09273948.2022.2027463
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Two Cases of Acute Macular Neuroretinopathy Associated with the Adenovirus-based COVID-19 Vaccine Vaxzevria (Astrazeneca)

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Cited by 13 publications
(4 citation statements)
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“…Several recent studies demonstrated evidence of retinal and choroid-targeted diseases including retinal vein occlusion (RVO), acute macular neuroretinopathy (AMN) and retinal artery occlusion (RAO) in the early phase of SARS-CoV-2 vaccination. [ 3 , [17] , [18] , [19] ] The pathogenesis of SARS-CoV-2 vaccine related side effects has not been clearly elucidated. Commonly proposed mechanisms are reactions caused by adjuvant component of vaccine, molecular mimicry, autoimmunity and hypersensitivity reaction.…”
Section: Discussionmentioning
confidence: 99%
“…Several recent studies demonstrated evidence of retinal and choroid-targeted diseases including retinal vein occlusion (RVO), acute macular neuroretinopathy (AMN) and retinal artery occlusion (RAO) in the early phase of SARS-CoV-2 vaccination. [ 3 , [17] , [18] , [19] ] The pathogenesis of SARS-CoV-2 vaccine related side effects has not been clearly elucidated. Commonly proposed mechanisms are reactions caused by adjuvant component of vaccine, molecular mimicry, autoimmunity and hypersensitivity reaction.…”
Section: Discussionmentioning
confidence: 99%
“… Publication Date Diagnosis Age Sex Hormonal Birth Control Use? Vaccine Onset of Symptoms After Vaccine September 1, 2021 17 AMN (bilateral) 20 Female Vaginal hormonal contraception Pfizer 2 days September 23, 2021 18 AMN (bilateral) 23 Female Oral contraception AstraZeneca 1 day November 17, 2021 19 AMN (bilateral) 21 Female No AstraZeneca 3 days January 1, 2022 20 AMN (unilateral) 22 Female No AstraZeneca 5 days January 1, 2022 21 AMN (bilateral) 26 Female Oral contraception Johnson & Johnson 2 days January 20, 2022 22 AMN (bilateral) 25 Female Oral contraception AstraZeneca 1 day January 20, 2022 23 AMN (bilateral) 31 Female Oral contraceptive AstraZeneca 2 days January 20, 2022 …”
Section: Discussionmentioning
confidence: 99%
“…Diverse Risikofaktoren wie weibliches Geschlecht, orale Kontrazeptiva, grippeähnliche Symptomatik, Dehydratation, Hypovolämie, Anämie, Trauma, Schock, Thrombozytopenie, Lupus erythematodes, Leukämie, Susac-Syndrom, Dengue-Fieber, systemische Wirkung von sympathomimetischem Lisdexamfetamin, aber auch intranasaler Kokainkonsum [ 2 – 4 ] wurden beschrieben. Zudem gibt es Hinweise auf eine Assoziation zwischen AMN und COVID-19-Impfungen [ 5 7 ] sowie AMN und COVID-19-Infektion [ 8 , 9 ].…”
Section: Diskussionunclassified