Twenty-one acylphloroglucinol derivatives and further constituents from south african Helichrysum species

In vitro biological activity and essential oil composition of four indigenous South African Helichrysum species

“…Some of these molecules contain phenolic hydroxyl groups and since the presence of these groups is associated with antibacterial activity (Tomás- Barberán et al, 1990), this may in part account for the observed activity. However, although very similar phenolic hydroxyl containing compounds were previously isolated from Helichrysum felinum and Helichrysum petiolare (Jakupovic et al, 1989) extracts from these plants were much less active. In a previous study on Helichrysum kraussii (Bremner and Meyer, 2000), two compounds; prenyl-butyrylphloroglucinol and kaurenoic acids were isolated.…”

“…Flavonoids, kaurenoic acid derivatives, cadinenes and guaianolides (Jakupovic et al, 1989) were previously isolated from Helichrysum dasyanthum. Some of these molecules contain phenolic hydroxyl groups and since the presence of these groups is associated with antibacterial activity (Tomás- Barberán et al, 1990), this may in part account for the observed activity.…”

Cytogenetic effects of nine Helichrysum taxa in human lymphocytes culture

“…This species can be useful in investigations regarding the increase of cell division. Furthermore, there are a lot of compounds in extracts of Helichrysum (Chinou et al 1997;Jakupovic et al 1989). The use of single constituents would allow more precise interpretation of data and the added effect of the numerous compounds will be lost.…”

“…These are presumably responsible for the remarkable antibacterial (Aslan et al 2006;Chinou et al 1997;Cosar and Cubukcu 1990;Kotan et al 2007;Rios et al 1991;Roussis et al 2002;Suzgec et al 2005), antiviral (Aslan et al 2006), antifungal (Aslan et al 2006), antioxidant (Aslan et al 2007a, b;Carini et al 2001;Suzgec et al 2005;Tepe et al 2005), anti-inflammatory (ElDahmy 1994Recio et al 1991), anti-allergic (Carini et al 2001) and antidiabetic (Aslan et al 2007a, b) properties of extracts from various Helichrysum species. Helichrysum species have been used in folk medicine for thousands of years in areas as far apart as Europe, Egypt, North America, China, Australia and South Africa (Cosar and Cubukcu 1990;Jakupovic et al 1989). Helichrysum species are traditionally used in the treatment of wounds, infections, and respiratory conditions (Hutchings et al 1996).…”

In vitro investigation of antitumor activities of extracts of endemic plant species Helichrysum zivojini ?ernjavski et So?ka U

“…Za biljke roda Helichrysum karakteristično je mnoštvo raznovrsnih sekundarnih metabolita, kao što su flavonoidi, fenolne kiseline, kumarini, acetofenoni, floroglucinoli, α-pironi, diterpeni, triterpeni i seskviterpeni [68,[76][77][78][79][80][81][82][83]. Od značaja je istaći da je kvalitativan i kvantitativan hemijski sastav u izvesnoj meri specifičan za određene morfološke grupe biljaka iz roda Helichrysum, kao i za vrste koje naseljavaju različite regione [68].…”