Twelve-month randomized controlled trial of 38% silver diamine fluoride with or without potassium iodide in indirect pulp capping of young permanent molars

Baraka, Marwa; Tekeya, Magda; Bakry, Niveen S.; Fontana, Margherita

doi:10.1016/j.adaj.2022.08.008

Cited by 5 publications

(16 citation statements)

References 34 publications

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“…Subsequently, Baraka et al ( 2022 ) indicated that there were no significant differences ( p = .26) with regard to secondary caries prevention, pain, and maintaining pulpal health in young permanent first molars with deep occlusal carious lesions by the employment of either resin‐modified GIC (RMGIC), 38% of SDF or SDF plus KI as indirect pulp capping materials followed by resin‐based composite restorations. All restorations were retained successfully without any symptoms of pulpal and apical pathology throughout the study, except for one in the SDF plus KI at 6 months and one in the SDF alone groups after 12 months.…”

Section: Resultsmentioning

confidence: 99%

“…The randomized controlled trial by Baraka et al ( 2022 ) was carried out a detailed blinding and allocation processes. Allocation was concealed from the investigators, participants, and statisticians.…”

Section: Resultsmentioning

confidence: 99%

“…Different durations for 11 studies were also noticed. Satyarup et al ( 2022 ) conducted the clinical study for a period of six months while Baraka et al ( 2022 ) had nine months only. Mauro et al ( 2004 ) and Zhang et al ( 2013 ) only reported results for the end of the study.…”

Section: Discussionmentioning

confidence: 99%

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A systematic review on the effect of silver diamine fluoride for management of dental caries in permanent teeth

Mungur

Chen

Shahid

et al. 2023

Clinical & Exp Dental Res

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Objectives The objective of this review is to assess the available literature systematically related to the effect of silver diamine fluoride (SDF) for the management of occlusal and root carious lesions in permanent teeth regardless of age. Materials and Methods This systematic review was conducted according to the Cochrane Handbook for Systematic Reviews of Interventions and Preferred Reporting Items for Systematic Review and Meta‐Analyses statement. A literature search was performed using PubMed/MEDLINE, Cochrane Central Register of Controlled Trials, Web of Science, DOAJ, and Open Gray with no language restrictions up to December 2022. Three reviewers critically assessed the studies for eligibility. Any disputes between the reviewers were handled by a fourth independent reviewer. The quality assessment and data extraction of the studies were performed. Results A total of 2176 studies were screened. The titles and abstracts of the studies were then reviewed ( n = 346), and 52 studies met the search criteria. Following the full‐text review, 11 studies investigated the effect of SDF against other treatments such as chlorhexidine, sodium fluoride, ammonium bifluoride, tricalcium silicate paste, casein phosphopeptide amorphous calcium phosphate, glass ionomer cement (GIC) combined with fluoride varnish, resin‐modified GIC, and atraumatic restorative treatment were assessed. Conclusions Within the limitations of this review, the use of SDF is promising with high preventative fractions in permanent teeth of children and older populations when compared to other topical applications such as dental varnish containing sodium fluoride.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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A systematic review on the effect of silver diamine fluoride for management of dental caries in permanent teeth

Mungur

Chen

Shahid

et al. 2023

Clinical & Exp Dental Res

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“…High fluoride-releasing materials such as silver diamine fluoride (SDF) and resin-modified glass ionomer cement (RMGIC) have been proposed as IPC materials due to their biocompatibility and induction of tertiary dentin deposition [Gupta et al, 2011;Sinha et al, 2011;Korwar et al, 2015;Baraka et al, 2022;Zaeneldin et al, 2022]. A systematic review evaluated the pulp response to calcium hydroxide and RMGIC in deep cavities and found no significant differences between the two materials [Mickenautsch et al, 2010].…”

Section: Introductionmentioning

confidence: 99%

“…SDF can arrest cavitated caries lesions, with likely minimal adverse effects to the pulp [Rossi et al, 2017;Seifo et al, 2019;Zaeneldin et al, 2022]. However, limited data are available regarding the pulpal status after SDF application on deep carious lesions (inner third of the dentin) in young permanent teeth [Gupta et al, 2011;Sinha et al, 2011;Korwar et al, 2015;Baraka et al, 2022;Zaeneldin et al, 2022].…”

Section: Introductionmentioning

confidence: 99%

Three-Dimensional Assessment of Radiographic Changes after Indirect Pulp Capping Using Silver Diamine Fluoride with or without Potassium Iodide in Young Permanent Teeth (12-Month RCT)

et al. 2023

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The aim was to have a three-dimensional evaluation of radiographic changes after indirect pulp capping (IPC) with silver diamine fluoride (SDF) with or without potassium iodide (KI) and resin modified glass ionomer cement (RMGIC) in deep carious young permanent molars using cone beam computed tomography (CBCT). 108 first permanent molars with deep occlusal cavitated caries lesions, in forty-nine 6–9-year-old children, were randomly allocated to one of 3 groups (n=36) and treated with SDF+KI, SDF and RMGIC as IPC materials. CBCT scans were taken at 0 and at 12-months to assess tertiary dentin formation (volume and grey level intensity), increase in root length, and pathological changes as secondary caries, periapical radiolucency, internal resorption and obliteration of the pulp. The three-dimensional image analysis procedures were performed using ITK-SNAP and 3D Slicer CMF. Comparisons were made using analysis of variance with a fixed effect for treatment and random effects for patient, and patient-by-treatment to account for within-patient correlations. A two-sided 5% significance level was used. There were no significant differences among the three groups regarding tertiary dentin volume (p=0.712) and grey level intensity (p=0.660), increase in root length (p=0.365), prevention of secondary caries (p=0.63) and periapical radiolucency (p=0.80) in the analysed 69 CBCT scans. The study did not find differences among the groups regarding quality and quantity of tertiary dentin formed, increase in root length, absence of secondary caries and other signs of failure as shown by CBCT. Clinical Significance: The results show no significant differences in radiographic outcomes (quality and quantity of tertiary dentin formed, increase in root length, absence of secondary caries and other signs of failure) when using SDF+KI, SDF and RMGIC in IPC. The results of this study can help guide treatment decision making regarding use of SDF and SDF+KI as IPC materials in deep cavitated lesions.

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SDF as an Adjunct Approach for the Management of Caries

Crystal

Rabieh

2023

Contemporary Endodontics for Children and Adolescents

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Twelve-month randomized controlled trial of 38% silver diamine fluoride with or without potassium iodide in indirect pulp capping of young permanent molars

Cited by 5 publications

References 34 publications

A systematic review on the effect of silver diamine fluoride for management of dental caries in permanent teeth

A systematic review on the effect of silver diamine fluoride for management of dental caries in permanent teeth

Three-Dimensional Assessment of Radiographic Changes after Indirect Pulp Capping Using Silver Diamine Fluoride with or without Potassium Iodide in Young Permanent Teeth (12-Month RCT)

SDF as an Adjunct Approach for the Management of Caries

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