TV Watching, but Not Physical Activity, Is Associated With Change in Kidney Function in Older Adults

Abstract

BACKGROUND Physical activity (PA) may play a role in preserving kidney health. The purpose of this study was to determine if PA and sedentary behavior are associated with incident chronic kidney disease (CKD) and change in kidney function in older adults. METHODS The Health, Aging and Body Composition study is a prospective cohort of 3,075 well-functioning older adults. PA and television watching was measured by self-report and serum cystatin C was used to estimate glomerular filtration rate (eGFR). CKD was defined as an eGFR <60 ml/min/1.73m2. Rapid kidney function decline was defined as an annual loss in eGFR of >3ml/min/1.73m2. Discrete survival analysis was used to determine if baseline PA and television watching were related to 10-year cumulative incidence of CKD and rapid decline in kidney function. RESULTS Individuals who reported watching television >3 hours/day had a higher risk of incident CKD (HR 1.34; 95% CI: 1.09, 1.65) and experiencing a rapid decline in kidney function (HR 1.26; 95% CI 1.05, 1.52) compared to individuals who watched television < 2 hours/day. PA was not related to either outcome. CONCLUSIONS High levels of television watching are associated with declining kidney function; the mechanisms that underlie this association need further study.

Characterization of Physical Activity and Sitting Time Among Patients on Hemodialysis Using a New Physical Activity Instrument

“…First, the LoPAQ is shorter than the Minnesota LTA and other similar instruments, taking approximately 10 minutes to administer, including instructions to participants, compared to the 20 minutes required for the Minnesota LTA. 17 Second, the LoPAQ also collects information about the amount of time spent in sedentary, sitting activities, which recent research suggests may be independently associated with adverse outcomes 8–11 and which could be targeted separately in interventions to increase physical activity (or decrease sedentariness). Finally, the focus on walking may be an advantage.…”

“…Finally, there is increasing recognition that, especially among sedentary populations, time spent sitting may have adverse effects on outcomes independent of the level of participation in activity. 8–11 …”

Leisure-time, occupational, and commuting physical activity and the risk of chronic kidney disease in a working population: a prospective cohort study

“…Physical activity is another important factor known to reduce cardiovascular risk [6] and is hypothesized to be an important modi able risk factor in the development of CKD, either directly or indirectly through favorable effects on diabetes, hypertension, and obesity [7,8]. Although physical inactivity has been reported as a risk factor of CKD in several cross-sectional studies [9][10][11][12], evidence from prospective studies has been limited and inconsistent [10,11,13].…”

“…The Australian Diabetes, Obesity, and Lifestyle (AusDiab) Study and the Health, Aging, and Body Composition (Health ABC) study have demonstrated that physical activity was not associated with risk of incident CKD [10,11]. By contrast, in a Taiwan cohort, a higher level of habitual physical activity was found to be associated with a lower risk of developing CKD [13].…”

“…In addition to the inconsistency in the association between physical activity and CKD, several other issues have not been addressed. First, cohort studies have focused on leisure-time physical activity alone or total physical activity (i.e., a combination of leisure-time and occupational physical activity) [10,11,13], but there is no evidence for the association in relation to other domains of physical activity, such as occupational or commuting physical activity. For a considerable fraction of the general population, work constitutes the main setting for physical activity [14].…”