Turn-on fluorescent sensor for the detection of lipopolysaccharides based on a novel bispyrenyl terephtalaldehyde-bis-guanylhydrazone

Abstract

A “turn-on” bispyrenyl sensor for lipopolysaccharide detection with unique molecular conformations exhibits excimer emission with sensitivity down to nanomolar.

Adsorption and Dehydration Reaction of Ethanol to Ethylene on Isomorphous B, Al, and Ga Substitution of H-ZSM-5 Zeolite: An Embedded ONIOM Study

“…[38] These effects on unsaturated aliphatic, aromatic and heterocyclic compounds were theoretically examined by a combination of second order Møller-Plesset perturbation theory (MP2) and hybrid density functional M06-2X. [39] The M06 functionals [40] developed by the Truhlar group had also been successfully used for studying adsorption and reactions on acidic Zeolites [39,41,42], on Lewis-acid zeolites [43,44], on metallic catalysts [45][46][47][48][49], and on organic molecules [50,51]. Recently they have been applied to determine P-NMR chemical shifts of phosphorus-modi ed CHA zeolite.…”

Ab initio study on the excited states of pyrene and its derivatives using multi-reference perturbation theory methods

“…[37][38][39][40][41][42] It is also used as a probe in chemosensors that detect particular metal ions [43][44][45][46][47][48][49][50][51] and molecules. [52][53][54][55] The properties of an excimer are closely related to those of the monomer. [56][57][58] Thus, the excited states of pyrene and its derivatives have been vigorously investigated and still continue to attract much interest from scientists with respect to both fundamental studies and practical applications.…”

A Tetraphenylethylene-Based Aggregation-Induced Emission Probe for Fluorescence Turn-on Detection of Lipopolysaccharide in Injectable Water with Sensitivity Down to Picomolar

“…Many nonenzymatic methods were thus developed to detect LPS, including electrochemical, surface plasmon resonance (SPR), colorimetric, and fluorescent sensors. − However, the electrochemical and SPR sensors frequently suffer from high requirements for electrode and chip preparation, while the sensitivity of colorimetric sensors makes it difficult for them to meet the clinical requirements. In contrast, fluorescent probes have the advantages of easy operation, online detection, and high sensitivity, showing great potential in LPS detection. − For examples, Wu et al prepared a peptide-functionalized polydiacetyl liposome-based fluorescence turn-on sensor to detect LPS at micromolar concentration. Wang et al reported an alkylated ammonium-pyrene probe for LPS detection at a limit of detection (LOD) of 100 nM .…”