In this study, it is aimed to determine the impacts on the economy of Turkey of inflation and unemployment that shape the economies of countries. In the study that included 1988 and 2019, Johansen Cointegration Test was carried out to determine whether there is any cointegration among the variables or not. It is determined that there is one cointegration equation between the series with Johansen Cointegration Test. After determining this relationship, the direction of the relationship between the variables was determined by Granger Causality Test and unilateral Granger causality has been observed between inflation-GDP, and inflation -unemployment. Finally, long-term coefficients were calculated by using FMOLS, CCR and DOLS methods. Also short term coefficient were calculated by using error correction model, and unemployment and inflation were determined to reduce GDP in the long term ve short term. According to the test results, inflation has triggered unemployment and both variables have a reducing effect on GDP. Increasing inflation and unemployment causes stagnation and decline in national economies. In order to avoid this negative result, policy makers should take steps to reduce inflation. In particular, production should be increased, new employment opportunities should be provided and monetary policies should be developed in line with market structures.