Turbiscan Lab® Expert analysis of the biological demulsification of a water-in-oil emulsion by two biodemulsifiers

Liu, Jia; Huang, Xiangfeng; Liu, Lu; Li, Mingxia; Xu, Jiang; Deng, Huiping

doi:10.1016/j.jhazmat.2011.03.028

Cited by 123 publications

(73 citation statements)

References 27 publications

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“…This method enables detection of any destabilization processes faster than those visible to the naked eye (Santos et al, 2013;TrujilloCayado et al, 2014). Creaming, sedimentation, coalescence and flocculation phenomena can be observed without the need of sample dilution (Liu et al, 2011). The Turbiscan Lab Expert instrument consists of a pulsed near-infrared light source and two synchronous transmission (T) and back-scattering (BS) detectors.…”

Section: Resultsmentioning

confidence: 99%

The tetrapeptide N-acetyl-Pro-Pro-Tyr-Leu in skin care formulations—Physicochemical and release studies

Olejnik

Schroeder

Nowak

2015

International Journal of Pharmaceutics

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Section: Resultsmentioning

confidence: 99%

The tetrapeptide N-acetyl-Pro-Pro-Tyr-Leu in skin care formulations—Physicochemical and release studies

Olejnik

Schroeder

Nowak

2015

International Journal of Pharmaceutics

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“…TurbiscanLab ® is useful to detect destabilization phenomena much earlier and also in a simpler way than other methods, since it is based on the measurement of backscattering (BS) and transmission (T) signals (Araújo et al, 2009;Celia et al, 2009;Marianecci et al, 2010;Liu et al, 2011).…”

Section: Stability Analysis Of Ln By Turbiscanlab ®mentioning

confidence: 99%

Design of cationic lipid nanoparticles for ocular delivery: Development, characterization and cytotoxicity

Fangueiro

Andreani

Egea

et al. 2014

International Journal of Pharmaceutics

128

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a b s t r a c tIn the present study we have developed lipid nanoparticle (LN) dispersions based on a multiple emulsion technique for encapsulation of hydrophilic drugs or/and proteins by a full factorial design. In order to increase ocular retention time and mucoadhesion by electrostatic attraction, a cationic lipid, namely cetyltrimethylammonium bromide (CTAB), was added in the lipid matrix of the optimal LN dispersion obtained from the factorial design. There are a limited number of studies reporting the ideal concentration of cationic agents in LN for drug delivery. This paper suggests that the choice of the concentration of a cationic agent is critical when formulating a safe and stable LN. CTAB was included in the lipid matrix of LN, testing four different concentrations (0.25%, 0.5%, 0.75%, or 1.0%wt) and how composition affects LN behavior regarding physical and chemical parameters, lipid crystallization and polymorphism, and stability of dispersion during storage. In order to develop a safe and compatible system for ocular delivery, CTAB-LN dispersions were exposed to Human retinoblastoma cell line Y-79. The toxicity testing of the CTAB-LN dispersions was a fundamental tool to find the best CTAB concentration for development of these cationic LN, which was found to be 0.5 wt% of CTAB.

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“…This is attribute to the dispersed oil droplets in the bottom water flow upward and the dispersed water droplets in the top coalesce and sediment. According to Liu et al [20], in the initial period, coalescence play a main role in the emulsion, proved by the decreasing of transmission. As the droplets become bigger, they migrated from top to the bottom.…”

Section: Stabilitymentioning

confidence: 99%

Rheological and Emulsification Behavior of Xinjiang Heavy Oil and Model Oils

Jing¹,

Tan²,

Hu³

et al. 2016

TOEFJ

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Abstract:Transparent model oils are commonly used to study the flow patterns and pressure gradient of crude oil-water flow in gathering pipes. However, there are many differences between the model oil and crude oils. The existing literatures focus on the flow pattern transition and pressure gradient calculation of model oils. This paper compares two most commonly used model oils (white mineral oil and silicon oil) with Xinjiang crude oil from the perspectives of rheological properties, oil-water interfacial tensions, emulsion photomicrographs and demulsification process. It indicates that both the white mineral oil and the crude oils are pseudo plastic fluids, while silicon oil is Newtonian fluid. The viscosity-temperature relationship of white mineral oil is similar to that of the diluted crude oil, while the silicon oil presents a less viscosity gradient with the increasing temperature. The oil-water interfacial tension can be used to evaluate the oil dispersing ability in the water phase, but not to evaluate the emulsion stability. According to the Turbiscan lab and the stability test, the model oil emulsion is less stable than that of crude oil, and easier to present water separation.

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Turbiscan Lab® Expert analysis of the biological demulsification of a water-in-oil emulsion by two biodemulsifiers

Cited by 123 publications

References 27 publications

The tetrapeptide N-acetyl-Pro-Pro-Tyr-Leu in skin care formulations—Physicochemical and release studies

The tetrapeptide N-acetyl-Pro-Pro-Tyr-Leu in skin care formulations—Physicochemical and release studies

Design of cationic lipid nanoparticles for ocular delivery: Development, characterization and cytotoxicity

Rheological and Emulsification Behavior of Xinjiang Heavy Oil and Model Oils

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