Tumours of peripheral nerves in the upper extremity: A 22-year epidemiological study

Abstract

Peripheral nerve tumours are uncommon. Our aims were to calculate the incidence and relative frequencies, to define sites of nerve tumours and to judge preoperative symptoms and outcomes of intervention. The results of 53 patients, with 68 tumours and histopathological diagnoses of true neoplasms, who had been operated on at the Department of Hand Surgery, Malmo, Sweden, between 1986 and 2007, were analysed. Schwannomas were the most common tumour (n=42). The incidence of schwannomas was 0.62/100 000 inhabitants/year in Malmo during that time period. The median nerve was most affected, closely followed by the ulnar and digital nerves. The preferred sites were the forearm, the thumb, and the digits. The most common preoperative symptom was pain. Loss of sensation was the most common postoperative complication. However, 33/53 patients (62%) were completely free of symptoms after excision. Patients should be provided with meticulous information preoperatively.

Schwanoma do Membro Superior: Análise Retrospectiva de 17 Casos

“…2,5,8 Assim, os sintomas não dependem das dimensões do tumor, mas do grau de compressão e ausên-cia de distensibilidade tecidular local. 2,8 Na mão e punho as queixas de dor são atribuíveis à reduzida expansibilidade das estruturas locais.…”

“…Manifesta-se habitualmente como lesão única de crescimento lento e indolor ao longo de vários anos, sem sintomas específicos. 1,2 Contudo, por vezes surge num contexto de múltiplas lesões, descrito na literatura em raros casos não associados a síndromes familiares. [3][4][5] Os schwanomas esporádicos manifestam-se sobretudo entre a terceira e sexta década sem predomínio de géne-ro.…”

“…Apesar de serem raros e corresponderem a menos de 5% -8% de todos os tumores do membro superior, 1,6,7 são os tumores benignos de origem neural mais frequentes neste segmento, seguidos dos neurofibromas. 1,2,6,7 Manifestam--se sobretudo na região flexora, devido à elevada concentração de estruturas nervosas neste compartimento. 6,7 Na mão e punho são raros, com uma taxa de 1% dos schwanomas reportados.…”

Dendritic fibromyxolipoma adherent to the median nerve in the forearm

“…The patient had no symptoms or impaired sensation after exploration, which is usually the case after excision of a benign schwannoma [8]. The tumour was easily excised, which is not the case for a granular cell tumour that may occur in the median or the ulnar nerve [9].…”

Case report: Intraneural perineurioma of the sciatic nerve in an adolescent – strategies for revealing the diagnosis

“…The most common nerve tumors are neurofibroma and Schwannoma; the latter is usually treated with enucleation and rarely with remaining symptoms or recurrence 1, 2. However, some pathological conditions with tumor formation may be difficult to reveal, since they develop insidiously in young patients and cause predominantly motor dysfunction with milder sensory involvement.…”