Tumours

Else, R. W.

doi:10.1002/9780470753316.ch58

Cited by 5 publications

(4 citation statements)

References 23 publications

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“…INTESTINAL adenocarcinomas are the most frequently reported type of tumours in sheep (Ross 1980) and have also been reported in other domestic animal species and in human beings (Johnstone and others 1983, Hamir 1985, McCoy and others 2009). In sheep, these tumours have a low incidence (Else 2007), although an incidence of up to 6 per cent in some populations has been documented (Simpson and Jolly 1974). In Norway, intestinal adenocarcinomas were described in 2.9 per cent of 1256 adult sheep submitted for postmortem examination over a period of eight‐and‐a‐half years at a research institute (Ulvund 1983).…”

Section: Figurementioning

confidence: 99%

Intestinal adenocarcinomas in three generations of sheep

Løken

Bjørnstad²,

Ersdal

2012

Veterinary Record

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Section: Figurementioning

confidence: 99%

Intestinal adenocarcinomas in three generations of sheep

Løken

Bjørnstad²,

Ersdal

2012

Veterinary Record

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“…Exposure to phenoxy and picolinic acid herbicides has been associated with higher incidences of ovine intestinal adenocarcinoma (Ulvund 1983, Newell and others 1984). Ingestion of bracken fern ( Pteridium aquilinum ), in conjunction with papillomavirus infection, is associated with oesophageal and bladder neoplasms in cattle (Hopkins 1986), and may have a similar role in sheep (Else 2007). The pasture grazed by this particular animal had never been treated with herbicides to the best of the owner's knowledge, and was free of bracken.…”

Section: Discussionmentioning

confidence: 99%

Intestinal adenocarcinoma in a Shetland ewe

Crilly

Smith

Sargison

2014

Vet Record Case Reports

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“…This left seven hips (four hips with staged FAI correction, three healthy control hips) of four sheep in the final study cohort. All sheep were 2.5 years old, corresponding to a mean age of approximately 22 human years [7,42]. The mean body weight was 67 6 6 kg (range, 63-75 kg).…”

Section: Study Design and Experimental Animalsmentioning

confidence: 99%

Do dGEMRIC and T2 Imaging Correlate With Histologic Cartilage Degeneration in an Experimental Ovine FAI Model?

Schmaranzer

Arendt

Liechti

et al. 2018

Clin Orthop Relat Res

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Background Biochemical MRI of hip cartilage such as delayed gadolinium-enhanced MRI of cartilage (dGEM-RIC) and T2 mapping is increasingly used to judge cartilage quality in the assessment of femoroacetabular impingement (FAI). The current evidence is sparse about which of these techniques yields a stronger correlation with histologic cartilage degeneration because of the difficulty in validating biochemical MRI techniques against histology in the clinical setting. Recently, an experimental ovine FAI model was established that induces chondrolabral damage and offers a validated platform to address these limitations. Questions/purposes In a sheep model, we asked: (1) Do dGEMRIC and/or T2 values of acetabular and femoral cartilage correlate with histologic cartilage degeneration as assessed with the Mankin score? (2) Do simultaneously measured dGEMRIC and T2 values correlate in an experimental ovine FAI model? Methods We performed an experimental pilot study on five female Swiss Alpine sheep (10 hips) that underwent postmortem MRI, including biochemical cartilage sequences, after a staged FAI correction had been performed on one side. No surgery was performed on the contralateral side, which The institution of one or more of the authors (BvR) has received, during the study period, funding from the Swiss National Science Foundation. One of the authors certifies that he (FS), or a member of his immediate family, has received or may receive grants, during the study period, in an amount of USD 10,000 to USD 100,000 from the Swiss National Science Foundation (Bern, Switzerland), outside the submitted work. One of the authors certifies that he (MT), or a member of his immediate family, has received or may receive grants, during the study period, in an amount of more than USD 1,000,001 from the Swiss National Science Foundation for the conduct of this work. Clinical Orthopaedics and Related Research® neither advocates nor endorses the use of any treatment, drug, or device. Readers are encouraged to always seek additional information, including FDA approval status, of any drug or device before clinical use. Each author certifies that his or her institution approved the animal protocol for this investigation and that all investigations were conducted in conformity with ethical principles of research.

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Tumours

Cited by 5 publications

References 23 publications

Intestinal adenocarcinomas in three generations of sheep

Intestinal adenocarcinomas in three generations of sheep

Intestinal adenocarcinoma in a Shetland ewe

Do dGEMRIC and T2 Imaging Correlate With Histologic Cartilage Degeneration in an Experimental Ovine FAI Model?

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