Tumors of the Mediastinum

Kennebeck, Stephanie

doi:10.1016/j.cpem.2005.05.003

Cited by 7 publications

(7 citation statements)

References 36 publications

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“…To determine the most likely etiology, an assessment should take place in consultation with an appropriate subspecialist. 1 In a single institutional review of all mediastinal tumors in 196 infants and children, 55 (28%) were benign masses and 141 (72%) were malignant. 4 The most frequent malignant diagnoses were Hodgkin lymphoma (33%), neuroblastoma (32%), and non-Hodgkin lymphoma (26%).…”

Section: Discussionmentioning

confidence: 99%

“…4 Lymphoma is the most common mediastinal malignancy in children and can arise in any compartment. 1 Most mediastinal lymphomas occur in the anterior and middle mediastinal compartments, arising from mediastinal lymph nodes. Hodgkin lymphomas are more common than non-Hodgkin lymphomas in children.…”

Section: Discussionmentioning

confidence: 99%

“…1 Within the posterior mediastinum, the most common tumors in children are of neurogenic origin, and approximately 50% are malignant. 2 Only one case of primary posterior mediastinal Burkitt lymphoma (BL) has been reported previously.…”

Section: Introductionmentioning

confidence: 99%

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Primary Burkitt lymphoma in the posterior mediastinum

Chaari

Abdessalem

Ayadi

et al. 2015

Asian Cardiovasc Thorac Ann

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A 13-year-old boy was admitted to our hospital with complaints of posterior chest pain and dyspnea. Computed tomography and magnetic resonance imaging of the chest revealed a mass in the posterior mediastinum, extending from T8 to T11 with intraspinal involvement. A percutaneous core needle biopsy confirmed the diagnosis of Burkitt lymphoma. He was treated according to the Lymphoma Malignancy B protocol 2001 arm C3, but he presented with liver and brain relapses and died 7.5 months after admission. Although lymphoma is rarely localized in the posterior mediastinum, it should be considered in the differential diagnosis of posterior mediastinal masses in children.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Primary Burkitt lymphoma in the posterior mediastinum

Chaari

Abdessalem

Ayadi

et al. 2015

Asian Cardiovasc Thorac Ann

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“…[3,5] The involved compartment will guide the differential diagnosis. [5] Haematological markers that are useful include a full blood count with differential and (looking for atypical lymphocytes or blasts, or cytopenias indicating possible bone marrow infiltration) tumour markers (alpha fetoprotein, beta human chorionic gonadotrophin (HCG)) in the case of germ cell tumours. A BMAT is necessary in the case of a suspected haematological malignancy, as one-third of patients will have bone marrow involvement.…”

Section: Fig 3 Hande Section Of the Mass Seen In Figures Revealing Exmentioning

confidence: 99%

“…Certain tumour markers may assist with a diagnosis: for instance, elevated alpha foetoprotein and beta HCG would suggest a germ cell tumour. [5] A peripheral flow cytometry conducted on a patient with a very high white cell count would suggest a lymphoma/leukaemia. Elevated urinary levels of the catecholamine vanillylmandelic acid (VMA) and homovanillic acid (HVA) in a patient with a posterior mediastinal mass is suggestive of a neuroblastoma.…”

Section: Fig 3 Hande Section Of the Mass Seen In Figures Revealing Exmentioning

confidence: 99%

Superior mediastinal masses in children – two cases of lymphoma

Jeevarathnum

Niekerk²,

Parris³

et al. 2016

S Afr Res J

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<div><p>The exact incidence of superior mediastinal masses in children is largely unknown. They present as a spectrum of disease ranging from an incidental finding on a Chest X-Ray to being markedly symptomatic with superior vena caval syndrome or obstruction of the upper airways. Lymphomas seem to be the most common causes of superior mediastinal masses in children. We present two cases of confirmed T cell lymphoma in children with superior mediastinal masses. In doing so, we explore a diagnostic approach and visit the complications the physician needs to be aware of when confronted with a child with a superior mediastinal mass.</p></div>

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