Tumors of the Hand and the Wrist

Strike, Sophia A.; Puhaindran, Mark E.

doi:10.2106/jbjs.rvw.19.00141

Cited by 8 publications

(20 citation statements)

References 59 publications

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“…One of the predictors of improved outcome was Caucasian race when compared to “others” ( p = 0.032, Table 3). This is a novel finding that has not been reported in the literature to the best of our knowledge 3,7 . “Others” include a total of 11 cases (Table 1) with two cases identifying as Native American, two as Asians, three as Filipinos, one as Haitian, two as Japanese, and one Vietnamese.…”

Section: Discussionmentioning

confidence: 82%

“…Primary osseous malignancies of the hand and wrist are extremely rare 1 and are associated with significant morbidity 2 . Anatomical and biomechanical complexity of hand and wrist, with critical neurovascular elements adjacent to osseous and musculo‐tendinous structures constitute unique surgical challenges 3 . Surgical challenges include preservation of essential anatomy to maintain function and dexterity 4,5 while achieving local tumor control with negative margins 6 .…”

Section: Introductionmentioning

confidence: 99%

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Prognostic factors, disparity, and equity variables impacting prognosis in bone sarcomas of the hand: SEER database review

Jawad

Bayne

Farhan

et al. 2021

Journal of Surgical Oncology

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Background: Primary sarcomas originating from the bones of hand and wrist are rare but carry a significant burden of morbidity. Methods: National Cancer Institute's Surveillance, Epidemiology and End Result database from 1975 to 2017 was queried to report incidence and survival data in 237 patients in the United States. Kaplan-Meier and Cox regression were used to determine the prognostic factors affecting survival. χ 2 test was used to assess the correlation.Results: Incidence of hand and wrist sarcoma was 0.017 per 100 000 persons in 2017 and has not significantly changed since 1975 (p > 0.05). Disease-specific 5-year and 10-year survival for the entire cohort was 90% and 84%, respectively. On multivariate analysis race "others," histology other than "osteosarcoma," "undifferentiated" grade, and size "≥6 cm" were predictors of worse disease-specific survival. Cross-tabulation of race with other significant prognostic factors on univariate analysis revealed a significant correlation of race with every other significant prognostic factor except for grade. Conclusions:The current study is an analysis of a population-based registry reporting incidence and survival data for patients with sarcoma of hand and wrist.Independent prognostic factors include race, histology, grade, and size. There is a lack of improvement in survival over the last four decades. How to cite this article: Jawad MU, Bayne CO, Farhan SB, et al. Prognostic factors, disparity, and equity variables impacting prognosis in bone sarcomas of the hand: SEER database review.

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Section: Discussionmentioning

confidence: 82%

Section: Introductionmentioning

confidence: 99%

Prognostic factors, disparity, and equity variables impacting prognosis in bone sarcomas of the hand: SEER database review

Jawad

Bayne

Farhan

et al. 2021

Journal of Surgical Oncology

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“…6; Additional file 2: Video 2). It is important to remember that all vascularised lesions do not necessarily have a vascular origin and that histopathologic analysis remains mandatory in most cases [6,[58][59][60].…”

Section: (B)mentioning

confidence: 99%

CT angiography and MRI of hand vascular lesions: technical considerations and spectrum of imaging findings

Blum¹,

Gillet²,

Athlani

et al. 2021

Insights Imaging

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Vascular lesions of the hand are common and are distinct from vascular lesions elsewhere because of the terminal vascular network in this region, the frequent hand exposure to trauma and microtrauma, and the superficial location of the lesions. Vascular lesions in the hand may be secondary to local pathology, a proximal source of emboli, or systemic diseases with vascular compromise. In most cases, ischaemic conditions are investigated with Doppler ultrasonography. However, computed tomography angiography (CTA) or dynamic contrast-enhanced magnetic resonance angiography (MRA) is often necessary for treatment planning. MR imaging is frequently performed with MRA to distinguish between vascular malformations, vascular tumours, and perivascular tumours. Some vascular tumours preferentially affect the hand, such as pyogenic granulomas or spindle cell haemangiomas associated with Maffucci syndrome. Glomus tumours are the most frequent perivascular tumours of the hand. The purpose of this article is to describe the state-of-the-art acquisition protocols and illustrate the different patterns of vascular lesions and perivascular tumours of the hand.

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“…The avoidance of biopsy is recommended in cases of expected benign pathology (22). Nevertheless, some authors still recommend biopsy for selected cases (35).…”

Section: Biopsymentioning

confidence: 99%

“…Complete resection can lead to local deformities and a risk of damage to critical internal structures (36). Overall prognosis is poor: the 5-year rate of survival ranges from 15% to 50% (35). Metastases are extremely rare, and may include lungs, pleura, the breast, or skin, among other localizations.…”

Section: Management Of Mpnstmentioning

confidence: 99%

Peripheral Nerve Tumors as an Ongoing Challenge in Neuro-oncology: An Overview of Their Biological and Technical Nuances

Matić

Lepić

Kovačević

et al. 2021

ama

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This paper aims to provide an overview of recent advances in the diagnosis and treatment of peripheral nerve tumors (PNTs) with regard to biological and technological nuances, and to highlight some recommendations for achieving better outcomes in the treatment of patients suffering from PNT. PNTs are probably the most challenging entity in the field of peripheral nervous system surgery. The goal of removing a nerve tumor while also preserving nerve function at the same time is often complicated, regardless of the surgeon’s experience. Still, in most cases, high-quality results can be achieved upon carefully planned surgery. Clinical presentation, diagnosis, and indications for a specific type of treatment of PNTs still remain a topic of debate. Recent technological advances have led to an exponential improvement in the field with utilization of intraoperative ultrasound, neurostimulation devices, and intraoperative electrophysiological monitoring, along with the development of modern surgical techniques, whereby a multidisciplinary and individually shaped approach is necessary.Conclusion. These advances, however, still remain limited, and recent research is focused on the development of biological therapy. Biologically targeted therapies will emerge when there is a better understanding of the genetic and molecular mechanisms driving the development and growth of PNTs.

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Tumors of the Hand and the Wrist

Cited by 8 publications

References 59 publications

Prognostic factors, disparity, and equity variables impacting prognosis in bone sarcomas of the hand: SEER database review

Prognostic factors, disparity, and equity variables impacting prognosis in bone sarcomas of the hand: SEER database review

CT angiography and MRI of hand vascular lesions: technical considerations and spectrum of imaging findings

Peripheral Nerve Tumors as an Ongoing Challenge in Neuro-oncology: An Overview of Their Biological and Technical Nuances

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