Tumor Vascularization in Cervical Cancer by 3-Dimensional Power Doppler Angiography

Abstract

Our data indicate that tumor vascularization as assessed by 3D-PDA correlates with some tumor features in cervical cancer.

The Role of Ultrasound in the Assessment of Uterine Cervical Cancer

“…They found blood flow in 85 % of the tumors and tumor vascularization was correlated with tumor volume [32]. On the other hand, Alcazar et al [33], Tanaka and Umesaki [34], and Belitsos et al [35] did find that tumor vascularization as assessed by 3D power ultrasound correlated with some tumor characteristics such as tumor stage and histologic grade.…”

Doppler Ultrasound Flow Evaluation of the Uterine Arteries Significantly Correlates with Tumor Size in Cervical Cancer Patients

“…However, in the last 20 years, neoadjuvant chemotherapy followed by radical surgery, as an alternative to chemoradiation, has been introduced in the management of this malignancy. 5 Suspicious areas caused by abnormal/irregular vascularization of the cervix can be simply identified via Doppler, and their intratumoral blood flow characteristics can be correlated with some tumoral features of the cervical cancer, 6 such as local extension. However, the correlation between blood flow in the uterine arteries and cervical cancer has been poorly investigated.…”

Contrast-enhanced ultrasonography of cervical carcinoma: perfusion pattern and relationship with tumour angiogenesis

“…Therefore, imaging of tumour angiogenesis has potential as a more promising indicator. [11][12][13][14] In previous studies, functional imaging modalities such as dynamic contrast-enhanced CT and MRI were evaluated to determine their usefulness in quantifying tumour perfusion, which is related to angiogenesis. Although these are practical modalities for assessing tissue perfusion, 11 the perfusion variables do not always correlate with histomorphometric features.…”

“…[11][12][13][14] However, some of these modalities may expose patients to ionizing radiation, while others have poor reproducibility.…”