Tumor estromal gastrointestinal: análise de 146 casos do centro de referência do Instituto Nacional do Câncer - INCA

Linhares, Eduardo; Gonçalves, Rinaldo; Valadão, Marcus; Vilhena, Bruno; Herchenhorn, Daniel; Romano, Sérgio; Ferreira, Maria Aparecida; Ferreira, Carlos Gil; Ramos, Cintia; Jesus, José Paulo de

doi:10.1590/s0100-69912011000600006

Cited by 10 publications

(2 citation statements)

References 58 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Histopathologic evaluation of GISTs usually shows predominant fusiform type (70%). The incidence of epithelioid and the mixed types was 20% and 10 % respectivally 13 , 23 . Cytological analysis of the surgical specimens demonstrated fusiform or spindle cell predominance (93%).…”

Section: Discussionmentioning

confidence: 94%

Laparoscopic Resection of Gastrointestinal Stromal Tumors (Gist)

Loureiro

Almeida

Claus

et al. 2016

ABCD, arq. bras. cir. dig.

View full text Add to dashboard Cite

Background Gastrointestinal mesenchymal or stromal tumors (GIST) are lesions originated on digestive tract walls, which are treated by surgical resection. Several laparoscopic techniques, from gastrectomies to segmental resections, have been used successfully. Aim Describe a single center experience on laparoscopic GIST resection. Method Charts of 15 operated patients were retrospectively reviewed. Thirteen had gastric lesions, of which ten were sub epithelial, ranging from 2-8 cm; and three were pure exofitic growing lesions. The remaining two patients had small bowel lesions. Surgical laparoscopic treatment consisted of two distal gastrectomies, 11 wedge gastric resections and two segmental enterectomies. Mechanical suture was used in the majority of patients except on six, which underwent resection and closure using manual absorbable sutures. There were no conversions to open technique. Results Mean operative time was 1h 29 min±92 (40-420 min). Average lenght of hospital stay was three days (2-6 days). There were no leaks, postoperative bleeding or need for reintervention. Mean postoperative follow-up was 38±17 months (6-60 months). Three patients underwent adjuvant Imatinib treatment, one for recurrence five months postoperatively and two for tumors with moderate risk for recurrence . Conclusion Laparoscopic GIST resection, not only for small lesions but also for tumors above 5 cm, is safe and acceptable technique.

show abstract

Section: Discussionmentioning

confidence: 94%

Laparoscopic Resection of Gastrointestinal Stromal Tumors (Gist)

Loureiro

Almeida

Claus

et al. 2016

ABCD, arq. bras. cir. dig.

View full text Add to dashboard Cite

show abstract

“…GISTs may also occur in the peritoneum, omentum and mesentery 1,5 . Most tumors are asymptomatic or present inconsequential symptoms such as abdominal pain (43%), upper gastrointestinal bleeding (15%) and palpable abdominal mass (17%), in addition to chronic anemia 5,6 . They occur most commonly in men and after 50 years of age 5 .…”

mentioning

confidence: 99%

Treatment of posterior gastric wall gastrointestinal stromal tumor with gastric sleeve: a case report

et al. 2018

View full text Add to dashboard Cite

Gastrointestinal stromal tumors (GISTs) are the most common non-epithelial tumors of the gastrointestinal tract. The most usual location is the stomach, followed by the small intestine, where it may cause digestive bleeding and anemia. Surgical resection of the tumor is the gold standard treatment, and definitive diagnosis is based on immunohistochemical analysis of the surgical specimen. We report the case of a 53-year-old man with gastric GIST presenting with endophytic and exophytic growth, located at the posterior wall of the stomach, in the antrum-body transitional zone, treated with gastric sleeve.

show abstract

The impact of additional malignancies in patients diagnosed with gastrointestinal stromal tumors

Smith

Mahar

et al. 2016

Intl Journal of Cancer

View full text Add to dashboard Cite

A higher incidence of additional malignancies has been described in patients diagnosed with gastrointestinal stromal tumors (GIST). This study aimed to identify risk factors for developing additional malignancies in patients diagnosed with GIST and evaluate the impact on survival. Individuals diagnosed with GIST from 2001 to2009 were identified from the SEER database. Logistic regression was used to identify predictors of additional malignancies and Cox‐proportional hazards regression used to identify predictors of survival. In the study period, 1705 cases of GIST were identified, with 181 (10.6%) patients developing additional malignancies. Colorectal cancer was the most common cancer developing within 6 months of GIST diagnosis (30%). The median time to diagnosis of a malignancy after 6 months of GIST diagnosis was 21.9 months. Older age (p < 0.0001) and extraoesophagogastric GIST (p = 0.0027) were significant prognostic factors associated with additional malignancies. The overall 5‐year survival was 65%, with the presence of additional malignancies within 6 months of GIST diagnosis associated with poor overall survival (54%, HR 1.55 1.05–2.3 95% CI, p = 0.04). Predictive factors of additional malignancies in patients diagnosed with GIST are increasing age and the primary disease site. Developing additional malignancies within 6 months of GIST diagnosis is associated with poorer overall survival. Targeted surveillance may be warranted in patients diagnosed with GIST that are at high risk of developing additional malignancies.

show abstract

Tumor estromal gastrointestinal: análise de 146 casos do centro de referência do Instituto Nacional do Câncer - INCA

Cited by 10 publications

References 58 publications

Laparoscopic Resection of Gastrointestinal Stromal Tumors (Gist)

Laparoscopic Resection of Gastrointestinal Stromal Tumors (Gist)

Treatment of posterior gastric wall gastrointestinal stromal tumor with gastric sleeve: a case report

The impact of additional malignancies in patients diagnosed with gastrointestinal stromal tumors

Contact Info

Product

Resources

About