1962
DOI: 10.3171/jns.1962.19.8.0679
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Tumor Cells in the Cerebrospinal Fluid

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Cited by 12 publications
(2 citation statements)
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“…Currently, the diagnosis generally is made after the onset of neurological manifestations and heralds a rapidly-fatal course for most patients. Immunocytochemistry techniques, immunophenotyping and biochemical or immunological markers can help in this diagnosis [56,57,66,[71][72][73][74][75][76][77][78]. The analysis of CSF biochemical and cellular characteristics, although not specific for the diagnosis of malignant involvement of the CNS, is important and can help with the diagnosis of CNS neoplasms, when associated with other clinical or biomarker characteristics.…”
Section: Carcinomatous Meningitismentioning
confidence: 99%
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“…Currently, the diagnosis generally is made after the onset of neurological manifestations and heralds a rapidly-fatal course for most patients. Immunocytochemistry techniques, immunophenotyping and biochemical or immunological markers can help in this diagnosis [56,57,66,[71][72][73][74][75][76][77][78]. The analysis of CSF biochemical and cellular characteristics, although not specific for the diagnosis of malignant involvement of the CNS, is important and can help with the diagnosis of CNS neoplasms, when associated with other clinical or biomarker characteristics.…”
Section: Carcinomatous Meningitismentioning
confidence: 99%
“…Primary cerebral tumors that exfoliated cells to the CSF were all located adjacent to the ventricle. In contrast, cells from tumors deeply localized in cerebral parenchyma are more difficult to find in the CSF [63][64][65][66][67][68].…”
Section: Carcinomatous Meningitismentioning
confidence: 99%