Tuberculous Arthritis—Unexpected Extrapulmonary Tuberculosis Detected by FDG PET/CT

Abstract

FDG PET/CT imaging has been used in various medical fields, including neoplastic and infectious diseases, for a long time. We reported a 62-year-old man with fever, chronic cough, arthralgia of the left side of the hip, and body weight loss. Chest radiograph showed increased infiltration in both upper lungs, and the acid-fast stain of sputum was positive. Whole-body PET/CT scan revealed a lesion with intense FDG uptake in the joint of the side left of the hip. Osteoarthritis of the hip was initially impressed by an orthopedist. However, tuberculous arthritis was subsequently confirmed by deep pus culture.

Diagnostic utility of 99mTc-EDDA-tricine-HYNIC-Tyr3-octreotate SPECT for differentiation of active from inactive pulmonary tuberculosis

“…Several radiotracers, such as gallium-67 citrate [14], 99m Tc-MIBI [15,16], and 99m Tc-(V)-dimercaptosuccinic acid [17], have been used in the evaluation of tuberculosis and its treatment. In addition, 18 F-FDG PET imaging seems to be a promising method with diagnostic application in tuberculosis and other granulomatous diseases such as sarcoidosis and in evaluating their therapeutic response [18,19].…”

Imaging in Tuberculosis

“…Cite this article as Cold Spring Harb Perspect Med 2015;5:a017814 in cases which were initially thought to be malignant (Wang and Lin 2006;Roudaut et al 2008;Ito et al 2010;Dong et al 2013;Wang et al 2013). HIV-positive patients are at increased risk of malignancy as well as TB, and FDG PET-CT scanning was found not to be useful in distinguishing these three entities (Sathekge et al 2010).…”

Diagnostic utility of PET/CT in a patient with miliary tuberculosis

“…On autopsy, multiple tuberculous lesions may be detected throughout the body in organs such as the lungs, liver, spleen, brain and others. There are many studies and case reports relevant to PET/CT utility that reveal the diagnostic and the thera-peutic response evaluation in tuberculosis patients [9][10][11][12][13][14][15][16][17][18][19][20][21]. These studies are about the organ involvement of mycobacterium tuberculosis infection while none of these papers have presented data concerning miliary tuberculosis.…”