Tuberculous and Nontuberculous Mycobacterial Infection of the Pancreas in a Patient with AIDS

Albu, Eugene; Yousuf, Arshad M.; Swaminathan, Krishnaswamy; Parikh, Virendra; Gerst, Paul H.

doi:10.1097/00006676-199605000-00015

Cited by 6 publications

(7 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…A total of 43 cases of HIV-positive patients with pancreatic TB (including the present case) were reviewed [2, . Of these cases, 40 were primarily analyzed [2,[5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][25][26][27][28][29][30][31][32][33][34][35][36][37][38] . Table 1 illustrates the clinical characteristics of the pancreatic TB patients with AIDS.…”

Section: Discussionmentioning

confidence: 99%

“…Gender [2,[5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][22][23][24][25][26][27][28][30][31][32][34][35][36][37][38] Male 28/39 (71.8) Female 11/39 (28.2) Known HIV-infected cases [2,[5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][25]…”

Section: Clinical Characteristics N (%)unclassified

“…n (%) Evidence of TB on chest X-rays [2,5,6,8-10,12-15,17-20,23-25,27-32,34 -37] 10/31 (32.3) Abnormal CT scans [2,[5][6][7][8][9][10][12][13][14][15][16][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36][37][38] Pancreatic/peripancreatic mass with or without diffuse pancreatic enlargement 34/36 (94.4) Only diffuse pancreatic enlargement 1/36 (2.8) Small nodular lesions 1/36 (2.8) Topographic lesions of the pancreatic mass from all imaging studies [2,[5][6][7][8][9][10]12,13,15,16,[18][19][20][21][22]…”

Section: Diagnostic Studiesmentioning

confidence: 99%

“…(n = 40) [2,[5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][25][26][27][28][29][30][31][32][33][34][35][36][37][38] (%) FNA with AFB staining and/or mycobacterial culture a 23 (57. a confirmed history of TB; in 3 cases, the patient had had a positive purified protein derivative skin test, and there were 2 cases of pulmonary TB. The median CD4 count (n = 21) was 54/mm 3 (range, 0-718/mm 3 ); 76.2% and 90.5% of the patients had a CD4 count ≤ 120 or ≤ 190/mm 3 , respectively.…”

Section: Investigations Yielding Definitive Diagnosismentioning

confidence: 99%

See 3 more Smart Citations

Pancreatic tuberculosis with acquired immunodeficiency syndrome: A case report and systematic review

Meesiri¹

2012

WJG

View full text Add to dashboard Cite

Pancreatic tuberculosis (TB) is a relatively rare disease that can mimic carcinoma, lymphoma, cystic neoplasia, retroperitoneal tumors, pancreatitis or pseudocysts. Here, I report the case of a 31-year-old immigrant Burmese woman who exhibited epigastralgia, fever, weight loss and an epigastric mass. The patient was diagnosed with pancreatic TB and acquired immunodeficiency syndrome, and was treated with antituberculous drugs and percutaneous catheter drainage without a laparotomy. The clinical presentation, radiographic investigation and management of pancreatic TB are summarized in this paper to emphasize the importance of considering this rare disease in the differential diagnosis of pancreatic masses concomitant with human immunodeficiency virus infection. I also emphasize the need for both histopathological and microbiological diagnosis via fine-needle aspiration.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Clinical Characteristics N (%)unclassified

Section: Diagnostic Studiesmentioning

confidence: 99%

Section: Investigations Yielding Definitive Diagnosismentioning

confidence: 99%

See 2 more Smart Citations

Pancreatic tuberculosis with acquired immunodeficiency syndrome: A case report and systematic review

Meesiri¹

2012

WJG

View full text Add to dashboard Cite

show abstract

“…At low CD4 counts (i.e., Ͻ 200 cells/mm 3 ), HIV patients are more susceptible to OIs. Numerous OIs, including cytomegalovirus, 23-25 varicella-zoster virus, 26 Mycobacterium tuberculosis, [27][28][29] Mycobacterium avium, 29,30 toxoplasmosis, 27,31 cryptococcosis, 32,33 and Pneumocystis jirovecii (formerly carinii), 33,34 have all been associated with pancreatic involvement. Medications for OI treatment and prevention, including pentamidine [35][36][37] and trimethoprim-sufamethoxazole, [38][39][40] have also been associated with pancreatitis, and these medications are predominantly prescribed for patients with the lowest CD4 counts.…”

Section: Nor Bush Andmentioning

confidence: 99%

A Ten-Year Analysis of the Incidence and Risk Factors for Acute Pancreatitis Requiring Hospitalization in an Urban HIV Clinical Cohort

Riedel

Gebo²,

Moore³

et al. 2008

AIDS Patient Care and STDs

View full text Add to dashboard Cite

To assess the incidence of and risk factors for acute pancreatitis in HIV-infected patients in the contemporary highly active antiretroviral therapy (HAART) era, we evaluated all cases of acute pancreatitis requiring hospitalization between 1996 and 2006 in patients followed at Johns Hopkins Hospital's HIV clinic. A nested, case-control analysis was employed for initial episodes of acute pancreatitis, and conditional logistic regression was used to assess risk factors. Of 5970 patients followed for 23,460 person-years (PYs), there were 85 episodes of acute pancreatitis (incidence: 3.6 events/1000 PYs). The incidence of pancreatitis from 1996 to 2000 was 2.6 events/1000 PYs; the incidence from 2001 to 2006 was 5.1 events/1000 PYs (p = 0.0014, comparing rates in two time periods). In multivariate regression, factors associated with pancreatitis included female gender (adjusted odds ratio [AOR] 2.96 [1.69, 5.19]; p < 0.001); stavudine use (AOR 2.19 [1.16, 4.15]; p = 0.016); aerosolized pentamidine use (OR 6.27; [1.42, 27.63]; p = 0.015); and CD4 count less than 50 cells/mm(3) (AOR 10.47 [3.33, 32.90]; p < 0.001). Race/ethnicity, HIV risk factor, HIV-1 RNA, and newer non-nucleoside reverse transcriptase inhibitors (NNRTI)- and protease inhibitor (PI)-based HAART regimens were not associated with an increased risk of pancreatitis after adjustment for the above factors. Pancreatitis remains a significant cause of morbidity in the HIV population in the HAART era. Acute pancreatitis is associated with female gender, severe immunosuppression, and stavudine and aerosolized pentamidine usage. Of note, newer antiretrovirals, particularly atazanavir, lopinivir/ritonavir, tenofovir, abacavir, and efavirenz, were not associated with an increased risk of pancreatitis.

show abstract

Infectious Causes of Acute Pancreatitis

Nesvaderani¹,

Eslick²,

Cox³

2019

Gastrointestinal Diseases and Their Associated Infections

View full text Add to dashboard Cite

Tuberculous and Nontuberculous Mycobacterial Infection of the Pancreas in a Patient with AIDS

Cited by 6 publications

References 0 publications

Pancreatic tuberculosis with acquired immunodeficiency syndrome: A case report and systematic review

Pancreatic tuberculosis with acquired immunodeficiency syndrome: A case report and systematic review

A Ten-Year Analysis of the Incidence and Risk Factors for Acute Pancreatitis Requiring Hospitalization in an Urban HIV Clinical Cohort

Infectious Causes of Acute Pancreatitis

Contact Info

Product

Resources

About