Tuberculosis of the spine. A systematic review of case series

Fuentes‐Ferrer, Manuel; Torres, Luisa Gutiérrez; Ramírez, Oscar Ayala; Zarzuelo, Mercedes Rumayor; González, Náyade del Prado

doi:10.1007/s00264-011-1414-4

Cited by 146 publications

(138 citation statements)

References 49 publications

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“…These data are very similar to the data reported by Song et al 5 and Ansari et al 10 The anatomical regions most affected in this study were the thoracic and lumbar regions; however, Rasouli et al, 12 Pu et al 13 and Fuentes et al 15 report that the most affected region is the thoracic region, as it is closer to the pulmonary region. The existence of two or more vertebrae affected by the tuberculosis is frequent, the most commonly affected vertebral bodies being L3 and L4.…”

Section: Discussionsupporting

confidence: 71%

“…The existence of two or more vertebrae affected by the tuberculosis is frequent, the most commonly affected vertebral bodies being L3 and L4. 12,13,15 Most patients were diagnosed during the first year of evolution of the disease. This is consistent with some studies such as those of Ansariy et al 10 and Moon et al, 16 who state that tuberculosis of spine is frequently reported from the first year of evolution, with a history of incidents of low back pain, sometimes accompanied by other symptoms such as loss of appetite, weight loss, or sweating, as symptoms with insidious onset.…”

Section: Discussionmentioning

confidence: 99%

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Spinal tuberculosis in western mexico, 2008-2013

Mora¹,

Ávila²,

Nakamura³

2014

Coluna/Columna

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Objective: To identify the prevalence, clinical features and postoperative outcome of patients with spinal tuberculosis at the Instituto Mexicano del Seguro Social, in Jalisco, Mexico from 2008 to 2013. Methods: Prevalence study of patients undergoing spine surgery due to tuberculosis. Clinical, surgical pre-and postoperative parameters were evaluated by analysis of 41 medical records.Results: Seventeen (41.4%) were women and 24 (58.6%) were men with a mean age of 47.7 years. The main diagnoses were tuberculous spondylitis in 14 (34.1%) patients; discitis in 13 (31.7%); infectious spondylitis in 9 (21.9%); chronic spondylitis in four (9.7%); abscess in one patient (2.4%). Only 22% of patients were positive for epidemiological study of tuberculosis contacts. The most affected region was the lumbar spine followed by the thoracic spine and the most affected vertebrae were L3-L4. The most used surgical instrumentation was by posterior approach with drainage on 29 occasions, anterior approach with drainage in nine, and the mixed approach in three. Twenty-nine patients were independent to perform daily activities after discharge.Conclusion: The discitis or infectious spondylodiscitis should be considered in any patient with localized pain at any level of the spine. Once solved the problem of infection and stability, patients respond favorably to the surgical procedure.

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Section: Discussionsupporting

confidence: 71%

Section: Discussionmentioning

confidence: 99%

Spinal tuberculosis in western mexico, 2008-2013

Mora¹,

Ávila²,

Nakamura³

2014

Coluna/Columna

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“…En la fase sintomática de la espondilitis tuberculosa, los síntomas son insidiosos e inicialmente inespecíficos; el malestar, la fiebre, la pérdida de apetito y de peso, así como la diaforesis nocturna, se presentan en alrededor de 20 a 30 % de los casos. La historia natural de la enfermedad puede extenderse a lo largo de meses o años, con un rango promedio de 4 a 11 meses (13). En el caso que se presenta aquí, transcurrieron cinco meses desde el inicio de los síntomas hasta la primera consulta y cerca de 18 hasta el diagnóstico exacto.…”

Section: Discussionunclassified

Mal de Pott en un indígena colombiano

et al. 2015

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“…1,4,6,9,11 Many of these patients are bed-bound due to paraplegia, requiring prolonged in-hospital stay and extended rehabilitation at an appropriate facility. This places an additional burden on an already strained health care system.…”

Section: Discussionmentioning

confidence: 99%

Costotransversectomy in thoracic spinal tuberculosis

Botha

2016

SA orthop. j.

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Background: The escalating global pandemic of tuberculosis infections results in 8 million new cases diagnosed each year. The thoracic and thoracolumbar spine is the most prevalent area involved in musculoskeletal tuberculosis. Deformity with associated neurological compromise, requiring extended in-patient treatment and rehabilitation, is common.Multidrug-resistant tuberculosis is prevalent and tissue samples are needed to obtain bacterial culture and sensitivity. Decompression of the spinal canal, directly or indirectly, should accelerate neurological recovery. Methods:A retrospective study was performed at Tygerberg Hospital to evaluate the efficacy of costotransversectomy in spinal thoracic tuberculosis with regard to neurological recovery and deformity. Neurological status was compared at 6 months post-operatively with the pre-surgical status. The end deformity was compared with Rajasakeran's equation.Results: Thirty patients met the inclusion criteria, with an average age of 37 years. Fifteen patients were HIV positive, and ten of them on highly active antiretroviral therapy (HAART). The average CD4 count was 235.The mean neurological status of the group was classified as Frankel C, but this improved to Frankel D at 6 months post-surgery. Initial sagittal deformity was 18.7°, which increased to 26° one year post-operatively. This was not significantly different from the 25.6° kyphosis predicted by the Rajasekaran formula. A 67% positive culture yield for TB was obtained which compared favourably to percutaneous transpedicular needle biopsies performed at the same institute which had a yield of 56%. Conclusions:Costotransversectomy is a simple procedure resulting in indirect decompression of the spinal cord, improving the microbiological diagnosis of spinal tuberculosis, and possibly leading to earlier neurological recovery, without the risk of creating further instability and greater deformity.

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Tuberculosis of the spine. A systematic review of case series

Cited by 146 publications

References 49 publications

Spinal tuberculosis in western mexico, 2008-2013

Spinal tuberculosis in western mexico, 2008-2013

Mal de Pott en un indígena colombiano

Costotransversectomy in thoracic spinal tuberculosis

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