Tuberculosis in Adults and Children

Abstract

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Diagnosis of Tuberculosis among Children and Adolescents

“…More recently, molecular methods of nucleic acid amplification (NAATs) have been advocated. Among these methods, the Gene-Xpert MTB/RIF method (Cepheid, California) was recommended by the WHO in 2013 to diagnose TB in childhood [5,7,8].…”

“…However, causes such as streptococcal infections, drug reactions, and leprosy, among others, should always be considered in these cases [4,8].…”

Rapid Molecular Detection of Tuberculosis and Rifampicine Resistance in Ecuador

“…A high clinical suspicion of pulmonary TB was defined by Heemskerk et al [11] as those clinical cases that included cough for ten or more days with abnormal chest x-ray (cavity, focal opacity, pleural effusion, nodule or lymphadenopathy) and at least one of the following symptoms: difficulty respiratory, fever, fatigue, night sweats, haemoptysis, coughing up blood, excessive sweating, especially during the night and chest pain, wheezing or weight loss.…”

Tuberculosis septic shock, an elusive pathophysiology and hurdles in management: A case report and review of literature

“…Mycobacterium tuberculosis is an acid-fast bacteria with a predominant pulmonary presentation [8] , though not a frequent cause of pneumonia in the western population. Only twenty percent of the cases have a sole extra-pulmonary manifestation [8] . The incidence of TB septic shock (TBSS) though not reported, is sporadic.…”