Tuberculosis: A Reemerging Disease at the Interface of Domestic Animals and Wildlife

Palmer, Mitchell V.

doi:10.1007/978-3-540-70962-6_9

Cited by 52 publications

(39 citation statements)

References 59 publications

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“…Because deer with more advanced disease are most likely to be excreting M. bovis in significant quantities (Schmitt et al, 1997;Palmer, 2007), they pose the greatest risk of exposure to uninfected wildlife and livestock. Consequently, they are the most important animals to cull from the population.…”

Section: Discussionmentioning

confidence: 99%

“…Several wild mammal species are implicated in the maintenance and transmission of Mycobacterium bovis infection and thereby impede national bovine TB control programs and international trade (Cousins, 2001;Palmer, 2007). Well-known examples of wildlife maintenance hosts include Eurasian badgers (Meles meles) in Great Britain and Ireland (Clifton-Hadley et al, 1993;Griffin et al, 2005), white-tailed deer (Odocoileus virginianus) in the United States (Schmitt et al, 1997;O'Brien et al, 2002O'Brien et al, , 2006, brushtail possums (Trichosurus vulpecula) in New Zealand (Coleman et al, 2006;Porphyre et al, 2007), wild boar (Sus scrofa) in Spain (Gortázar et al, 2003;Naranjo et al, 2008), and African buffalo (Syncerus caffer) in South Africa (Michel et al, 2006).…”

Section: Introductionmentioning

confidence: 99%

“…The successful eradication of bovine TB from livestock in countries with a wildlife reservoir is likely to require focusing on the wildlife reservoir(s) of M. bovis infection (Palmer, 2007). Current methods of diagnosis in live animals, such as the intradermal tuberculin test or interferon-gamma (IFN-g) release assays, are not fully validated for species other than cattle (Monaghan et al, 1994).…”

Section: Introductionmentioning

confidence: 99%

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Animal-side serologic assay for rapid detection of Mycobacterium bovis infection in multiple species of free-ranging wildlife

Lyashchenko¹,

Greenwald²,

Esfandiari³

et al. 2008

Veterinary Microbiology

116

108

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Lyashchenko, K.P.; Greenwald, R.; Esfandiari, J.; Chambers, M.A.; Vicente, J.; Gortazar, C.; Santos, N.; Correia-Neves, M.; Buddle, B.M.; Jackson, R.; O'Brien, D.J.; Schmitt, S.; Palmer, M. V.; Delahay, R.J.; and Waters, W.R., "Animal-side serologic assay for rapid detection of Mycobacterium Bovis infection in multiple species of free-ranging wildlife" (2008 AbstractNumerous species of mammals are susceptible to Mycobacterium bovis, the causative agent of bovine tuberculosis (TB). Several wildlife hosts have emerged as reservoirs of M. bovis infection for domestic livestock in different countries. In the present study, blood samples were collected from Eurasian badgers (n = 1532), white-tailed deer (n = 463), brushtail possums (n = 129), and wild boar (n = 177) for evaluation of antibody responses to M. bovis infection by a lateral-flow rapid test (RT) and multiantigen print immunoassay (MAPIA). Magnitude of the antibody responses and antigen recognition patterns varied among the animals as determined by MAPIA; however, MPB83 was the most commonly recognized antigen for each host studied. Other seroreactive antigens included ESAT-6, CFP10, and MPB70. The agreement of the RT with culture results varied from 74% for possums to 81% for badgers to 90% for wild boar to 97% for white-tailed deer. Small numbers of wild boar and deer exposed to M. avium infection or paratuberculosis, respectively, did not cross-react in the RT, supporting the high specificity of the assay. In deer, whole blood samples reacted similarly to corresponding serum specimens (97% concordance), demonstrating the potential for field application. As previously demonstrated for badgers and deer, antibody responses to M. bovis infection in wild boar were positively associated with advanced disease. Together, these findings suggest that a rapid TB assay such as the RT This article is a U.S. government work, and is not subject to copyright in the United States.may provide a useful screening tool for certain wildlife species that may be implicated in the maintenance and transmission of M. bovis infection to domestic livestock. #

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Animal-side serologic assay for rapid detection of Mycobacterium bovis infection in multiple species of free-ranging wildlife

Lyashchenko¹,

Greenwald²,

Esfandiari³

et al. 2008

Veterinary Microbiology

116

108

View full text Add to dashboard Cite

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“…It will not be possible to eradicate M. bovis from livestock until transmission between wildlife and domestic animals is halted. Such an endeavor will require a collaborative effort between agricultural, wildlife, environmental and political interests (Palmer 2007). Nowadays, TB is among the wildlife diseases receiving more attention by scientists and government agencies.…”

Section: Mycobacterial Diseases In European Wildlifementioning

confidence: 99%

“…In the last decade, however, resources for studying wildlife diseases increased after the identification of wildlife species as actors in the epidemiology of important livestock diseases, such as Aujeszky's disease (Müller et al 1998), bluetongue ) and bovine tuberculosis (bTB; Naranjo et al 2008), and more recently after realizing the importance of diseases in Iberian lynx (Lynx pardinus) conservation (Millán et al 2009). Risk factors for the appearance of wildlife reservoirs are commonly the spillover from domestic livestock in combination with anthropogenic activities such as translocation of wildlife, supplemental feeding of wildlife and wildlife populations reaching densities beyond normal habitat carrying capacities (Gortazar et al 2006;Palmer 2007). This, along with the size of the Spanish livestock industry and the significant proportion of free range breeding systems, prompted specific calls for wildlife disease research in the national grant scheme in 2008 (INIA-FAU, http://sp.inia.…”

Section: Introductionmentioning

confidence: 99%

Six recommendations for improving monitoring of diseases shared with wildlife: examples regarding mycobacterial infections in Spain

et al. 2011

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Monitoring is needed to identify changes in disease occurrence and to measure the impact of intervention. Using mycobacterial diseases as an example, we discuss herein the pros and cons of the current Spanish Wildlife Disease Surveillance Scheme providing suggestions for monitoring relevant diseases shared with wildlife in other regions facing similar challenges. Six points should be considered. This includes: (1) making sure the disease is properly monitored in the relevant domestic animals or even in humans; (2) also making sure that background information on wildlife population ecology is available to maximize the benefits of the monitoring effort; (3) selecting the appropriate wildlife hosts for monitoring, while being flexible enough to incorporate new ones if research suggests their participation; (4) selecting the appropriate methods for diagnosis and for time and space trend analysis; (5) deciding which parameters to target for monitoring; and finally (6) establishing a reasonable sampling effort and a suitable sampling stratification to ensure detecting changes over time and changes in response to management actions. Wildlife disease monitoring produces knowledge that benefits at least three different agencies, namely, animal health, public health and conservation, and these should combine efforts and resources. Setting up stable, comprehensive and accurate schemes at different spatial scales should become a priority. Resources are always a limiting factor, but experience shows that combined, cross-collaborative efforts allow establishing acceptable schemes with a low enough cost to be sustainable over time. These six steps for monitoring relevant shared diseases can be adapted to many other geographical settings and different disease situations.

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Forecasting eradication of bovine tuberculosis in Michigan white‐tailed deer

et al. 2014

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Bovine tuberculosis (bTB) caused by Mycobacterium bovis infection in Michigan white‐tailed deer (Odocoileus virginianus) has proven resistant to current management practices. The Michigan Department of Natural Resources (MDNR) is faced with managing a protracted bTB outbreak with shrinking economic resources, its initial control strategies approaching, or having reached, the limits of their effectiveness. Planning tools are needed to project the outbreak's future course and forecast the likely outcomes of proposed controls. We describe development of a spatially explicit, individual‐based stochastic simulation model of bTB in Michigan white‐tailed deer. We sought to 1) characterize whether eradication of bTB is possible by increasing hunter harvest or via vaccination, and how long it is likely to take to achieve eradication; 2) characterize the effect of concurrent deer baiting; and 3) assess the effect of baiting on the probability of bTB establishment in uninfected areas. Simulations indicated that current MDNR management strategies are unlikely to eradicate bTB from the core outbreak area's deer population within the next 30 years. A 50–100% increase (over current rates) of both antlered and antlerless deer harvest was required to achieve eradication if baiting was occurring, compared to only a 50% increase in harvest required if baiting was eliminated. Vaccination strategies required frequent application and high exposure rates (>90%) to achieve eradication, which baiting delayed. Simulations indicated that if bTB was eradicated from the core outbreak area, a single infected deer introduced into the area would be 8 times more likely to re‐establish bTB if baiting was occurring. The ability to forecast likely outcomes of disease management can be critical for wildlife managers to assess whether specific strategies are likely to be successful. Because current policy appears unlikely to achieve the stated goal of eradicating bTB from Michigan in the foreseeable future, reorienting the bTB program from eradication to controlling geographic spread and transmission to cattle may be more realistic goals. Spatial models such as ours are ideally suited to investigating spatial heterogeneity of disease transmission, and how transmission is influenced by aggregating factors such as baiting or supplemental feeding. © 2014 The Wildlife Society.

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Tuberculosis: A Reemerging Disease at the Interface of Domestic Animals and Wildlife

Cited by 52 publications

References 59 publications

Animal-side serologic assay for rapid detection of Mycobacterium bovis infection in multiple species of free-ranging wildlife

Animal-side serologic assay for rapid detection of Mycobacterium bovis infection in multiple species of free-ranging wildlife

Six recommendations for improving monitoring of diseases shared with wildlife: examples regarding mycobacterial infections in Spain

Forecasting eradication of bovine tuberculosis in Michigan white‐tailed deer

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