Tuberculoma presenting as an en plaque meningioma

Bauer, Jerry; Johnson, Roger F.; Levy, Joseph M.; Pojman, Donald V.; Ruge, John R.

doi:10.3171/jns.1996.85.4.0685

Cited by 40 publications

(43 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…1,3,11) The most common manifestation is tuberculous meningitis. 4) Intracranial tuberculoma may occur in intra-or extra-axial locations, but is frequently located in the Intracranial Tuberculoma of the Falx cerebral parenchyma.…”

Section: Discussionmentioning

confidence: 99%

“…4) Intracranial tuberculoma may occur in intra-or extra-axial locations, but is frequently located in the Intracranial Tuberculoma of the Falx cerebral parenchyma. 1,4) Extra-axial tuberculoma is likely to mimic meningioma on CT and MR imaging. However, tuberculomas mimicking meningiomas are exceptional, and only eight cases have been reported.…”

Section: Discussionmentioning

confidence: 99%

“…The tuberculin reaction is positive in 25-75% of cases. 1,5,6,10) Cerebrospinal fluid findings may show only mild elevation of protein, 5,6) and other examinations, such as smears, cultures, and PCR, are not definitive. Therefore, the diagnosis of tuberculoma is based on the results of all examinations.…”

Section: Discussionmentioning

confidence: 99%

“…Therefore, the diagnosis of tuberculoma is based on the results of all examinations. 2,5,10) Tuberculoma in the first stage of formation (pregranulomatous stage) appears as low density without enhancement by CT, 1,11) and hypo-or isointense on T 1 -weighted images and isointense on T 2 -weighted images. 1,3,4,10) Tuberculoma that has proceeded to the granulomatous stage with central necrosis, a cheesy necrotic lesion, appears as isodense or slightly hyperdense with a central lowdensity area by CT, 1,6) with uniform enhancement by contrast medium, 5,11) and iso-or hypointense on T 1 -weighted images, 1,3) with uniform enhancement of the central necrosis by gadolinium, [4][5][6]10) and isointense on T 2 -weighted images.…”

Section: Discussionmentioning

confidence: 99%

“…1,3,4,10) Tuberculoma that has proceeded to the granulomatous stage with central necrosis, a cheesy necrotic lesion, appears as isodense or slightly hyperdense with a central lowdensity area by CT, 1,6) with uniform enhancement by contrast medium, 5,11) and iso-or hypointense on T 1 -weighted images, 1,3) with uniform enhancement of the central necrosis by gadolinium, [4][5][6]10) and isointense on T 2 -weighted images. 1,3,[4][5][6]10) These imaging and histological characteristics apply to this case, so we thought that this case was the granulomatous stage with central necrosis. Some tuberculomas may mimic meningioma with dural-tail sign, 10) as observed in our case.…”

Section: Discussionmentioning

confidence: 99%

See 4 more Smart Citations

Tuberculoma Mimicking Falx Meningioma-Case Report-

Adachi

Yoshida

Tomita

et al. 2004

Neurol. Med. Chir.(Tokyo)

View full text Add to dashboard Cite

A 25-year-old male presented with an intracranial tuberculoma mimicking falx meningioma manifesting as right lower monoparesis. The patient had a past history of pulmonary tuberculosis, cured by antituberculous therapy. Computed tomography and magnetic resonance (MR) imaging showed a lesion mimicking a falx meningioma. Surgery achieved subtotal resection. Histological and biochemical examinations revealed the surgical specimen was tuberculoma. He was treated with antituberculous therapy, and his gait disturbance disappeared. Follow-up MR imaging showed no regrowth.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Tuberculoma Mimicking Falx Meningioma-Case Report-

Adachi

Yoshida

Tomita

et al. 2004

Neurol. Med. Chir.(Tokyo)

View full text Add to dashboard Cite

show abstract

Surgery for brain tuberculosis: a review

Rajshekhar

2015

Acta Neurochir

View full text Add to dashboard Cite

The two main manifestations of brain tuberculosis that require surgery are hydrocephalus associated with tuberculous meningitis (TBMH) and brain tuberculomas. TBMH most often responds to medical therapy but surgery is required promptly for those who fail medical therapy. Both ventriculoperitoneal (VP) shunt and endoscopic third ventriculostomy (ETV) are valid options although the latter is more often successful in patients with chronic hydrocephalus than in those with acute meningitis. Patients with TBMH are more prone to complications following VP shunt than other patients. The outcome of these patients is determined by the Vellore grade (I to IV) of the patients prior to surgery with those in good grades (I and II) having a better outcome and those in the worst grade (IV) having a high mortality in excess of 80 %. Patients with brain tuberculomas present clinically with features of a brain mass, indistinguishable clinically from other pathologies. CT and MR features might provide a probable diagnosis of a tuberculoma but most often a histological diagnosis is desirable. Empiric medical therapy is reserved for a small number of patients. Although the treatment of brain tuberculomas is essentially medical, surgery is required when the diagnosis is in doubt, to reduce raised intracranial pressure or local mass effect and to obtain tissue for culture and sensitivity studies. Stereotactic biopsy, stereotactic craniotomy and excision of superficial small tuberculomas and microsurgery are all procedures used to manage brain tuberculomas. The outcome in patients with brain tuberculomas is good if the tuberculous bacillus is sensitive to the anti-tuberculous therapy. The duration of therapy is debated but we suggest at least 18 months of combination therapy with three or four anti-tuberculous drugs and continue the therapy till the tuberculoma has resolved on neuro-imaging.

show abstract

Coexistence between meningioma and tuberculosis: case report

et al. 2010

View full text Add to dashboard Cite

Intracranial tuberculoma generally presents as either solitary or multiple lesions in the brain parenchyma. These are characterized by a ring-enhancing area on either computerized tomography scans or magnetic resonance images. A 66 year-old female with a history of breast carcinoma at 41 years, treated with radical mastectomy and radio and chemotherapy, and rheumatoid arthritis, treated in the last 10 years, presented two months ago with occipital headache, nausea, cerebellar syndrome, alterations of speech, and memory loss. The TC scan showed occipital enhancement by contrast and surrounded by oedema, suggesting metastasis. Histology showed a benign meningioma with many multinuclear giant cells, granulomas, and central caseating necrosis. In addition, some classic plasma cells, mastocytes, and lymphocytes were also detected. The authors describe the unusual case of coexistence between an occipital meningioma and tuberculosis in the same area that resembled metastasis.

show abstract

Tuberculoma presenting as an en plaque meningioma

Cited by 40 publications

References 15 publications

Tuberculoma Mimicking Falx Meningioma-Case Report-

Tuberculoma Mimicking Falx Meningioma-Case Report-

Surgery for brain tuberculosis: a review

Coexistence between meningioma and tuberculosis: case report

Contact Info

Product

Resources

About