Tube feeding with a diabetes-specific feed for 12 weeks improves glycaemic control in type 2 diabetes patients

Vaisman, Nachum; Lansink, Mirian; Rouws, C.; Laere, Katrien M. van; Segal, Refael; Niv, Eva; Bowling, Tim; Waitzberg, Dan Linetzky; Morley, John E.

doi:10.1016/j.clnu.2009.05.004

Cited by 43 publications

(36 citation statements)

References 22 publications

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“…We want to point out that a 0.3% HbA1 reduction represent an improvement of the glycaemic control in well-controlled diabetics patients feed the DSF during 6 weeks. Similar results were observed in a longer-term trial that evaluated a different enteral formula specific for diabetic patients (16). This improvement may be caused by the presence in the new formula of slowly digestible carbohydrates, low-dextrose equivalent malto- dextrins and resistant-starch type IV, which are characterized by a low GI (9).…”

Section: Discussionsupporting

confidence: 70%

A new fructose-free, resistant-starch type IV-enriched enteral formula improves glycaemic control and cardiovascular risk biomarkers when administered for six weeks to elderly diabetic patients

Mesa

García-Rodríguez²,

Rico³

et al. 2017

Nutr Hosp

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CM, Pérez-Rodríguez M, Pérez-de-laCruz AJ, Gil Á. A new fructose-free, resistant-starch type IV-enriched enteral formula improves glycaemic control and cardiovascular risk biomarkers when administered for 6 weeks to elderly diabetic patients. AbstractBackground: Reducing the dietary glycaemic response has been proposed as a way to reduce the risk of diabetes complications. Objective: The aim of the present study was to evaluate the glycaemic control and cardiovascular risk biomarkers in fragile, elderly type 2 diabetes patients after the intake of a new fructose-free diabetes-specifi c formula enriched with resistant-starch type IV and high in monounsaturated fatty acids. Methods: Forty-one type 2 diabetes patients aged 78.9 ± 2.8 years were fed exclusively with an enteral diabetes-specifi c formula for 6 weeks. Data were collected at baseline and after 6 weeks of feeding. Carbohydrate and lipid metabolism and infl ammatory and cardiovascular risk biomarkers were measured to evaluated the course of diabetes complications. Results: Blood glycated haemoglobin signifi cantly decreased after the intervention (6.1 ± 0.1 vs. 5.8 ± 0.1 %; p < 0,045), as well as monocyte chemotactic protein-1 and soluble E-selectin (p < 0.05), while soluble vascular cell adhesion molecule and plasminogen activator inhibitor-1 tended to decrease from baseline to 6 weeks (p = 0.084 and p = 0.05, respectively). Conclusion:The new product improves glycaemic control and cardiovascular risk without altering lipid metabolism, which is useful for the prevention of diabetic complications. Longer intervention studies are needed in order to validate these results in a larger population.

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Section: Discussionsupporting

confidence: 70%

A new fructose-free, resistant-starch type IV-enriched enteral formula improves glycaemic control and cardiovascular risk biomarkers when administered for six weeks to elderly diabetic patients

Mesa

García-Rodríguez²,

Rico³

et al. 2017

Nutr Hosp

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“…Some contain normal to high amounts of sugars for healthy individuals and those with compromised (reduced) nutritional intake, whilst others are low in sugars or contain slow-release carbohydrates suitable for diabetics or people at risk of hyperglycaemia. Earlier studies that report the metabolic response to standard oral nutritional supplements and disease-specific formulas mainly come from studies in Caucasians [8, 9]. It is important to understand whether these metabolic effects are applicable to Asians.…”

Section: Introductionmentioning

confidence: 99%

Glycaemic responses to liquid food supplements among three Asian ethnic groups

2015

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Purpose A limited number of studies have compared the glycaemic index (GI) and glycaemic responses (GR) to solid foods between Caucasians and Asians. These studies have demonstrated that Asians have greater GI and GR values for solid foods than Caucasians. However, no study has compared the GI and GR to liquids among various Asian ethnic groups.MethodsA total of forty-eight males and females (16 Chinese, 16 Indians, and 16 Malay) took part in this randomised, crossover study. Glycaemic response to the reference food (glucose beverage) was measured on three occasions, and GR to three liquids were measured on one occasion each. Liquids with different macronutrient ratio’s and carbohydrate types were chosen to be able to evaluate the response to products with different GIs. Blood glucose concentrations were measured in duplicate at baseline (−5 and 0 min) and once at 15, 30, 45, 60, 90, and 120 min after the commencement of beverage consumption.ResultsThere were statistically significant differences in GI and GR between the three liquids (P < 0.01 in all cases). However, there were no statistically significant differences in GI and GR for the liquids between the ethnic groups (Chinese vs. Indian vs. Malay).ConclusionThe GR for three different types of liquid nutritional supplements did not differ between the three main ethnic groups in Asia. It appears that the GI of liquid food derived from one Asian ethnicity can be applicable to other Asian populations.

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“…In a randomized, controlled, double blind, parallel group study in twenty-five type 2 diabetic patients on tube feeding, soy protein based, multi fibre diabetes specific food for 12 weeks, HbA1C decreased over time [26]. A randomized, double blind, crossover trial of dietary supplementation with phytoestrogens (soy protein 30 g/day, isoflavones 132 mg/day) versus placebo (cellulose 30 g/day) for 12 weeks, separated by a 2 week washout period, to postmenopausal women with type 2 diabetes, the phytoestrogen supplementation demonstrated significantly lower mean values of HbA1C [27].…”

Section: Discussionmentioning

confidence: 99%

Effect of Dietary Soy Protein Supplement in Dyslipidemic South Indian Population: A Randomized, Double-Blind, Placebo Controlled, Parallel-Group Trial

Narayanan¹,

Sethupathy²,

Saravanan³

et al. 2015

J Hypertens (Los Angel)

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Tube feeding with a diabetes-specific feed for 12 weeks improves glycaemic control in type 2 diabetes patients

Cited by 43 publications

References 22 publications

A new fructose-free, resistant-starch type IV-enriched enteral formula improves glycaemic control and cardiovascular risk biomarkers when administered for six weeks to elderly diabetic patients

A new fructose-free, resistant-starch type IV-enriched enteral formula improves glycaemic control and cardiovascular risk biomarkers when administered for six weeks to elderly diabetic patients

Glycaemic responses to liquid food supplements among three Asian ethnic groups

Effect of Dietary Soy Protein Supplement in Dyslipidemic South Indian Population: A Randomized, Double-Blind, Placebo Controlled, Parallel-Group Trial

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